The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
A Link Between Cyclin A Expression and Adhesion-Dependent Cell Cycle Progression
Abstract
Cell adhesion has an essential role in regulating proliferation during the G 1 phase of the cell cycle, and loss of this adhesion requirement is a classic feature of oncogenic transformation. The appearance of cyclin A messenger RNA and protein in late G 1 was dependent on cell adhesion in both NRK and NIH 3T3 fibroblasts. In contrast, the expression of Cdc2, Cdk2, cyclin D1, and cyclin E was independent of adhesion in both cell lines. Transfection of NRK cells with a cyclin A complementary DNA resulted in adhesion-independent accumulation of cyclin A protein and cyclin A-associated kinase activity. These transfected cells also entered S phase and complete multiple rounds of cell division in the absence of cell adhesion. Thus, cyclin A is a target of the adhesion-dependent signals that control cell proliferation.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Role of cell shape in growth control
Folkman, J., & Moscona, A. (1978) · Nature · doi:10.1038/273345a0 · Cited by 2,422
Matsushime, H., Ewen, M. E., Strom, D. K., Kato, J.-Y., Hanks, S. K., Roussel, M. F., & Sherr, C. J. (1992) · Cell · doi:10.1016/0092-8674(92)90360-o · Cited by 897
Benecke, B.-J., Ben-Ze'ev, A., & Penman, S. (1978) · Cell · doi:10.1016/0092-8674(78)90347-1 · Cited by 291
Ajchenbaum, F., Ando, K., DeCaprio, J. A., & Griffin, J. D. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)53587-0 · Cited by 237
Cited by
Sherr, C. J. (1996) · Science · doi:10.1126/science.274.5293.1672 · Cited by 5,379
Gilmore, A. P., & Romer, L. H. (1996) · Molecular Biology of the Cell · doi:10.1091/mbc.7.8.1209 · Cited by 513
Dannenberg, J.-H., van Rossum, A., Schuijff, L., & te Riele, H. (2000) · Genes & Development · doi:10.1101/gad.847700 · Cited by 413
Integrin cytoplasmic interactions and bidirectional transmembrane signalling
Dedhar, S., & Hannigan, G. E. (1996) · Current Opinion in Cell Biology · doi:10.1016/s0955-0674(96)80107-4 · Cited by 382
Cyclin D1-mediated inhibition of repair and replicative DNA synthesis in human fibroblasts
Pagano, M., Theodoras, A. M., Tam, S. W., & Draetta, G. F. (1994) · Genes & Development · doi:10.1101/gad.8.14.1627 · Cited by 294
Metadata
- Authors
- Guadagno, T. M., Ohtsubo, M., Roberts, J. M., & Assoian, R. K.
- Venue
- Science
- Published
- 1993-12-03
- Volume
- 262
- Issue
- 5139
- Pages
- 1572-1575
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2010307195
- Cited by
- 394
- References
- 4
- FWCI
- 17.84
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: A Link Between Cyclin A Expression and Adhesion-Dependent Cell Cycle Progression. https://app.cochat.ai/papers/10.1126/science.8248807
- The paper
- Guadagno, T. M., Ohtsubo, M., Roberts, J. M., & Assoian, R. K. (1993). A Link Between Cyclin A Expression and Adhesion-Dependent Cell Cycle Progression. Science. https://doi.org/10.1126/science.8248807
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
