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Knotting of a DNA Chain During Ring Closure

Shaw, Stanley Y., Wang, James C.·1993·Science

Abstract

The formation of knotted species on random ring closure of two DNAs that are 5.6 kilobase pairs (kbp) and 8.6 kbp in length was measured, and these data were used to calculate the effective DNA helix diameter as a function of sodium ion and magnesium ion concentration. In the presence of more than 50 mM magnesium ion, interactions between DNA segments appear to be attractive rather than repulsive. The free energy of formation of relaxed trefoil and figure-eight DNA knots and of supercoiled trefoil DNA knots was also evaluated.

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Metadata

Authors
Shaw, S. Y., & Wang, J. C.
Venue
Science
Published
1993-04-23
Volume
260
Issue
5107
Pages
533-536
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2064230672
Cited by
294
References
0
FWCI
4.75
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Knotting of a DNA Chain During Ring Closure. https://app.cochat.ai/papers/10.1126/science.8475384
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Shaw, S. Y., & Wang, J. C. (1993). Knotting of a DNA Chain During Ring Closure. Science. https://doi.org/10.1126/science.8475384

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.