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Cited by 533

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

The structure of the human mitochondrial ribosome

Open access
Amunts, Alexey, Brown, Alan, Toots, Jaan, Scheres, Sjors H. W., Ramakrishnan, V.·2015·Science

Abstract

The whole mitoribosome at high resolution: Mitochondria are thought to be the descendents of a prokaryotic cell that took up residence in a protoeukaryotic cell. Mitochondria retain a few genes involved in oxidative phosphorylation. To translate these genes, mitochondria contain highly divergent mitochondrial ribosomes, or mitoribosomes. Amunts et al. determined the high-resolution structures of complete mammalian mitoribosomes using cryoelectron microscopy. Mitoribosomes include an unusual mRNA binding channel. The findings elucidate how aminoglycoside antibiotics can inadvertently inhibit mitoribosomes and how mutations in mitoribosomes can lead to disease. Science , this issue p. 95

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Crossref · 10.1126/science.aaa1193

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Metadata

Authors
Amunts, A., Brown, A., Toots, J., Scheres, S. H. W., & Ramakrishnan, V.
Venue
Science
Published
2015-04-03
Volume
348
Issue
6230
Pages
95-98
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2006035995
Cited by
533
References
3
FWCI
20.46
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: The structure of the human mitochondrial ribosome. https://app.cochat.ai/papers/10.1126/science.aaa1193
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Amunts, A., Brown, A., Toots, J., Scheres, S. H. W., & Ramakrishnan, V. (2015). The structure of the human mitochondrial ribosome. Science. https://doi.org/10.1126/science.aaa1193

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.