The DOI matches its Crossref record; 32 of the 32 references it cites were found in a registry or an index.
O–H hydrogen bonding promotes H-atom transfer from α C–H bonds for C-alkylation of alcohols
Open accessAbstract
A trio helps activate C-H bonds in alcohols: Enzymes can accelerate chemical reactions by activating specific portions of a molecule through well-placed H bonds. Jeffrey et al. showcase the power of H-bonding in a synthetic context. Here, reactivity at the C centers of alcohols is selectively induced by using an H-bonding catalyst to bind the hydroxyl group of the alcohol. The adjacent C-H bonds now become susceptible to a reaction accelerated by another pair of catalysts. In combination, the trio of catalysts promotes C-C bond formation at the alcohol C within an array of competing sites. Science , this issue p. 1532
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Density-functional thermochemistry. III. The role of exact exchange
Becke, A. D. (1993) · The Journal of Chemical Physics · doi:10.1063/1.464913 · Cited by 103,767
Lee, C., Yang, W., & Parr, R. G. (1988) · Physical Review B · doi:10.1103/physrevb.37.785 · Cited by 100,874
Density-functional exchange-energy approximation with correct asymptotic behavior
Becke, A. D. (1988) · Physical Review A · doi:10.1103/physreva.38.3098 · Cited by 53,711
Stephens, P. J., Devlin, F. J., Chabalowski, C. F., & Frisch, M. J. (1994) · The Journal of Physical Chemistry · doi:10.1021/j100096a001 · Cited by 23,248
Self-consistent molecular orbital methods. XX. A basis set for correlated wave functions
Krishnan, R., Binkley, J. S., Seeger, R., & Pople, J. A. (1980) · The Journal of Chemical Physics · doi:10.1063/1.438955 · Cited by 17,772
Density Functional Theory of Atoms and Molecules
Parr, R. G. (1980) · Horizons of Quantum Chemistry · doi:10.1007/978-94-009-9027-2_2 · Cited by 11,964
Ditchfield, R., Hehre, W. J., & Pople, J. A. (1971) · The Journal of Chemical Physics · doi:10.1063/1.1674902 · Cited by 10,612
Prier, C. K., Rankic, D. A., & MacMillan, D. W. C. (2013) · Chemical Reviews · doi:10.1021/cr300503r · Cited by 9,590
Self-citationPurification of Laboratory Chemicals
(2003) · Elsevier eBooks · doi:10.1016/b978-0-7506-7571-0.x5000-5 · Cited by 8,730
Clark, T., Chandrasekhar, J., Spitznagel, G. W., & Schleyer, P. V. R. (1983) · Journal of Computational Chemistry · doi:10.1002/jcc.540040303 · Cited by 7,224
Metadata
- Authors
- Jeffrey, J. L., Terrett, J. A., & MacMillan, D. W. C.
- Venue
- Science
- Published
- 2015-09-25
- Volume
- 349
- Issue
- 6255
- Pages
- 1532-1536
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2140617505
- Cited by
- 594
- References
- 32
- FWCI
- 20.23
- Type
- journal article
- Language
- en
- Open access
- green
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- Jeffrey, J. L., Terrett, J. A., & MacMillan, D. W. C. (2015). O–H hydrogen bonding promotes H-atom transfer from α C–H bonds for C-alkylation of alcohols. Science. https://doi.org/10.1126/science.aac8555
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