The DOI matches its Crossref record; 48 of the 48 references it cites were found in a registry or an index.
HIV-1 therapy with monoclonal antibody 3BNC117 elicits host immune responses against HIV-1
Open accessAbstract
Insights into antibody therapy for HIV-1: Despite the success of antiretroviral therapy, HIV-1-infected individuals still harbor latent virus. Thus, other therapeutic strategies are needed. A single injection of a broad and potent monoclonal antibody targeting the HIV-1 envelope protein reduced viral loads in HIV-1-infected individuals, albeit only transiently. Lu et al. now report that antibody treatment not only blocked free virus from infecting new cells, it also accelerated the clearance of infected cells. Furthermore, Schoofs et al. demonstrate that therapeutic antibody treatment enhanced infected individuals' humoral response against the virus. Thus, neutralizing antibodies may be a promising therapy for HIV-1 because of their potential to reduce the viral reservoir. Science , this issue pp. 1001 and 997
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Clustal W and Clustal X version 2.0
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jModelTest 2: more models, new heuristics and parallel computing
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Antibody neutralization and escape by HIV-1
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Self-citationRational Design of Envelope Identifies Broadly Neutralizing Human Monoclonal Antibodies to HIV-1
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Self-citationBroad neutralization coverage of HIV by multiple highly potent antibodies
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Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding
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Self-citationStructural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01
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Mendoza, P., Gruell, H., Nogueira, L., Pai, J. A., Butler, A. L., Millard, K., Lehmann, C., Suárez, I., Oliveira, T. Y., Lorenzi, J. C. C., et al. (2018) · Nature · doi:10.1038/s41586-018-0531-2 · Cited by 521
Self-citationEffect of HIV Antibody VRC01 on Viral Rebound after Treatment Interruption
Bar, K. J., Sneller, M. C., Harrison, L. J., Justement, J. S., Overton, E. T., Petrone, M. E., Salantes, D. B., Seamon, C. A., Scheinfeld, B., Kwan, R. W., et al. (2016) · New England Journal of Medicine · doi:10.1056/nejmoa1608243 · Cited by 455
Self-citationSequential Immunization Elicits Broadly Neutralizing Anti-HIV-1 Antibodies in Ig Knockin Mice
Escolano, A., Steichen, J. M., Dosenovic, P., Kulp, D. W., Golijanin, J., Sok, D., Freund, N. T., Gitlin, A. D., Oliveira, T., Araki, T., et al. (2016) · Cell · doi:10.1016/j.cell.2016.07.030 · Cited by 320
Self-citationEarly antibody therapy can induce long-lasting immunity to SHIV
Nishimura, Y., Gautam, R., Chun, T.-W., Sadjadpour, R., Foulds, K. E., Shingai, M., Klein, F., Gazumyan, A., Golijanin, J., Donaldson, M., et al. (2017) · Nature · doi:10.1038/nature21435 · Cited by 312
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Metadata
- Authors
- Schoofs, T., Klein, F., Braunschweig, M., Kreider, E. F., Feldmann, A., Nogueira, L., Oliveira, T., Lorenzi, J. C. C., Parrish, E. H., Learn, G. H., West, A. P., Bjorkman, P. J., Schlesinger, S. J., Seaman, M. S., Czartoski, J., McElrath, M. J., Pfeifer, N., Hahn, B. H., Caskey, M., & Nussenzweig, M. C.
- Venue
- Science
- Published
- 2016-05-20
- Volume
- 352
- Issue
- 6288
- Pages
- 997-1001
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2346116821
- Cited by
- 313
- References
- 48
- FWCI
- 29.88
- Type
- journal article
- Language
- en
- Open access
- green
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- Schoofs, T., Klein, F., Braunschweig, M., Kreider, E. F., Feldmann, A., Nogueira, L., Oliveira, T., Lorenzi, J. C. C., Parrish, E. H., Learn, G. H., West, A. P., Bjorkman, P. J., Schlesinger, S. J., Seaman, M. S., Czartoski, J., McElrath, M. J., Pfeifer, N., Hahn, B. H., Caskey, M., & Nussenzweig, M. C. (2016). HIV-1 therapy with monoclonal antibody 3BNC117 elicits host immune responses against HIV-1. Science. https://doi.org/10.1126/science.aaf0972
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
