Intersection of diverse neuronal genomes and neuropsychiatric disease: The Brain Somatic Mosaicism Network

McConnell, Michael J., Moran, John V., Abyzov, Alexej, Akbarian, Schahram, Bae, Taejeong, Cortes-Ciriano, Isidro, Erwin, Jennifer A., Fasching, Liana +69 more·2017·Science

DOI 10.1126/science.aal1641

Cited by (272)

Items 101–200 of 272

Implementation of a Hamming distance–like genomic quantum classifier using inner products on ibmqx2 and ibmq_16_melbourne
Kunal Kathuria, Aakrosh Ratan, Michael J. McConnell, Stefan Bekiranov · 2020 · Quantum Machine Intelligence
Illegitimate and Repeated Genomic Integration of Cell-Free Chromatin in the Aetiology of Somatic Mosaicism, Ageing, Chronic Diseases and Cancer
Gorantla Venkata Raghuram, Shahid Chaudhary, Shweta Dilip Johari, Indraneel Mittra · 2019 · Genes
A microglia clonal inflammatory disorder in Alzheimer’s disease
Vicario, Rocio, Fragkogianni, Stamatina, Weber, Leslie, Lazarov, Tomi, Hu, Yang, Hayashi, Samantha Y, Craddock, Barbara, Socci, Nicholas D, Alberdi, Araitz, Baako, Ann et al. · 2025 · eLife
In search of optimal resilience ratios: Differential influences of neurobehavioral factors contributing to stress-resilience spectra
Kelly Gurley Lambert, Richard G Hunter, Andrew A. Bartlett, Hannah E. Lapp, Molly Kent · 2019 · Frontiers in Neuroendocrinology
What a finding of gene copy number variation can add to the diagnosis of developmental neuropsychiatric disorders
Jacob A. S. Vorstman, Stephen W. Scherer · 2021 · Current Opinion in Genetics & Development
Somatic Mosaicism in Biology and Disease
Hayato Ogawa, Keita Horitani, Yasuhiro Izumiya, Soichi Sano · 2021 · Annual Review of Physiology
Assessment of somatic single-nucleotide variation in brain tissue of cases with schizophrenia
John F. Fullard, Alexander W. Charney, Georgios Voloudakis, Andrew V. Uzilov, Vahram H. Haroutunian, Panos Roussos · 2019 · Translational Psychiatry
Causes and Consequences of Genome Instability in Psychiatric and Neurodegenerative Diseases
Ivan Yu. Iourov, Svetlana G. Vorsanova, О С Куринная, Maria A. Zelenova, Kirill S. Vasin, Yuri B. Yurov · 2021 · Molecular Biology
Genome integrity and neurogenesis of postnatal hippocampal neural stem/progenitor cells require a unique regulator Filia
Jing-Zheng Li, Ya-Fang Shang, Lin Wang, Bo Zhao, Chunli Sun, Jia-Li Li, Siling Liu, Cong Li, Min Tang, Fei-Long Meng et al. · 2020 · Science Advances
Early developmental origins of cortical disorders modeled in human neural stem cells
Xoel Mato-Blanco, Suel–Kee Kim, Alexandre Jourdon, Shaojie Ma, Sang-Hun Choi, Alice Maria Giani, Miguel I. Paredes, Andrew T.N. Tebbenkamp, Fuchen Liu, Alvaro Duque et al. · 2025 · Nature Communications
Analysis of LINE1 Retrotransposons in Huntington’s Disease
Lavinia Floreani, Federico Ansaloni, Damiano Mangoni, Elena Agostoni, Remo Sanges, Francesca Persichetti, Stefano Gustincich · 2022 · Frontiers in Cellular Neuroscience
Induction of recurrent break cluster genes in neural progenitor cells differentiated from embryonic stem cells in culture
Aseda Tena, Yuxiang Zhang, Nia Kyritsis, Anne Devorak, Jeffrey Zurita, Pei‐Chi Wei, Frederick W. Alt · 2020 · Proceedings of the National Academy of Sciences
The “missing heritability”—Problem in psychiatry: Is the interaction of genetics, epigenetics and transposable elements a potential solution?
Dietrich van Calker, Tsvetan Serchov · 2021 · Neuroscience & Biobehavioral Reviews
APP gene copy number changes reflect exogenous contamination
Junho Kim, Boxun Zhao, August Yue Huang, Michael B. Miller, Michael A. Lodato, Christopher A. Walsh, Eunjung Alice Lee · 2020 · Nature
Somatic and de novo Germline Variants of MEDs in Human Neural Tube Defects
Tian Tian, Xuanye Cao, Yongyan Chen, Lei Jin, Zhiwen Li, Xiao Han, Ying Linda Lin, Bogdan J. Wlodarczyk, Richard H. Finnell, Zhengwei Yuan et al. · 2021 · Frontiers in Cell and Developmental Biology
Human Molecular Neurocytogenetics
Yuri B. Yurov, Svetlana G. Vorsanova, Ivan Yu. Iourov · 2018 · Current Genetic Medicine Reports
Structural diverseness of neurons between brain areas and between cases
Ryuta Mizutani, Rino Saiga, Yoshiro Yamamoto, Masayuki Uesugi, Akihisa Takeuchi, Kentaro Uesugi, Yasuko Terada, Yoshio Suzuki, Vincent De Andrade, Francesco De Carlo et al. · 2021 · Translational Psychiatry
Somatic mosaicism in the diseased brain
Ivan Yu. Iourov, Svetlana G. Vorsanova, О С Куринная, Sergey Ivanovich Kutsev, Yuri B. Yurov · 2022 · Molecular Cytogenetics
Aggression in BALB/cJ mice is differentially predicted by the volumes of anterior and midcingulate cortex
Sabrina van Heukelum, Lisa Drost, Floriana Mogavero, Amanda Jager, Martha Nari Havenith, Jeffrey Colm Glennon · 2018 · Brain Structure and Function
Possible Causes of Discordance in Refraction in Monozygotic Twins: Nearwork, Time Outdoors and Stochastic Variation
Xiaohu Ding, Yin Chang Hu, Xinxing Guo, Xiaobo Guo, Ian George Morgan, Mingguang He · 2018 · Investigative Ophthalmology & Visual Science
A characterization of postzygotic mutations identified in monozygotic twins
Klaasjan G. Ouwens, Rick Jansen, Bas Tolhuis, P. Eline Slagboom, Brenda W.J.H. Penninx, Dorret Irene Boomsma · 2018 · Human Mutation
Can Grail find the trail to early cancer detection?
Clare Fiala, Eleftherios P. Diamandis · 2018 · Clinical Chemistry and Laboratory Medicine (CCLM)
Mapping recurrent mosaic copy number variation in human neurons
Chen Sun, Kunal Kathuria, Sarah B. Emery, Byung-Jun Kim, Ian E. Burbulis, Joo Heon Shin, Brain Somatic Mosaicism Network, Joseph G. Gleeson, Martin W. Breuss, Xiaoxu Yang et al. · 2024 · Nature Communications
Frequent monoallelic or skewed expression for developmental genes in CNS-derived cells and evidence for balancing selection
Sergio Branciamore, Zuzana Valo, Min Li, Jinhui Wang, Arthur D. Riggs, Judith Singer–Sam · 2018 · Proceedings of the National Academy of Sciences
Somatic mutations – Evolution within the individual
Satoshi Oota · 2019 · Methods
The L1-dependant and Pol III transcribed Alu retrotransposon, from its discovery to innate immunity
Ludwig Stenz · 2021 · Molecular Biology Reports
Slc35a2 mosaic knockout impacts cortical development, dendritic arborisation, and neuronal firing
James Spyrou, Khaing Phyu Aung, Hannah Kate Vanyai, Richard Jacob Leventer, Snezana Maljevic, Paul J. Lockhart, Katherine B. Howell, Christopher A. Reid · 2024 · Neurobiology of Disease
Genome-wide mutation detection by interclonal genetic variation
Javier R. Revollo, Azra Dad, L. Patrice McDaniel, Mason G. Pearce, Vasily N. Dobrovolsky · 2018 · Mutation Research/Genetic Toxicology and Environmental Mutagenesis
Early life experience shapes neural genome
Saera Song, Joseph G. Gleeson · 2018 · Science
Exploratory analysis of L1 retrotransposons expression in autism
Giovanni Spirito, Michele Filosi, Enrico Domenici, Damiano Mangoni, Stefano Gustincich, Remo Sanges · 2023 · Molecular Autism
Protective Mechanisms Against DNA Replication Stress in the Nervous System
Clara Forrer Charlier, Rodrigo A. P. Martins · 2020 · Genes
Причины и последствия геномной нестабильности при психических и нейродегенеративных заболеваниях
Yuri B. Yurov, Svetlana G. Vorsanova, О С Куринная, Maria A. Zelenova, Kirill S. Vasin, Yuri B. Yurov · 2020 · Molecular Biology
Investigation of Somatic Mutations in Human Brains Targeting Genes Associated With Parkinson's Disease
M. Leija-Salazar, A. Pittman, K. Mokretar, H. Morris, A. Schapira, C. Proukakis · 2020 · Frontiers in Neurology
The Landscape of Mutational Mosaicism in Autistic and Normal Human Cerebral Cortex
Rachel E. Rodin, Yan-Mei Dou, Minseok Kwon, Maxwell A. Sherman, Alissa M. D'Gama, Ryan N. Doan, Lariza Rento, Kelly M. Girskis, Craig L. Bohrson, S. Kim et al. · 2020 · bioRxiv
Types of DNA damage and research progress
Nian Liu, Xiaohua Li, Li Rongcheng, Liu Song-Bai · 2023 · Nucleosides Nucleotides & Nucleic Acids
Increased DNA Copy Number Variation Mosaicism in Elderly Human Brain
Darine Villela, Claudia K. Suemoto, Renata Elaine Paraízo Leite, Carlos Augusto Pasqualucci, Lea T. Grinberg, Peter Lees Pearson, Carla Rosenberg · 2018 · Neural Plasticity
Transcriptional Noise and Somatic Mutations in the Aging Pancreas
Avital Swisa, Klaus H. Kaestner, Yuval Dor · 2017 · Cell Metabolism
Genetics of Alcohol Use Disorder: A Role for Induced Pluripotent Stem Cells?
Iya Prytkova, Alison Goate, Ronald P. Hart, Paul A. Slesinger · 2018 · Alcoholism Clinical and Experimental Research
Topologically Guided Prioritization of Candidate Gene Transcripts Coexpressed with the 5-HT1A Receptor by Combining In Vivo PET and Allen Human Brain Atlas Data
Jakob Unterholzner, Gregor Gryglewski, Cécile Philippe, René Seiger, Verena Pichler, Godber Mathis Godbersen, Neydher Berroterán-Infante, Matej Murgaš, Andreas Hahn, Wolfgang Wadsak et al. · 2019 · Cerebral Cortex
Somatic retrotransposition in the developing rhesus macaque brain
Victor Billon, Francisco Jose Sanchez-Luque, Jay Rasmussen, Gabriela Oana Bodea, Daniel J. Gerhardt, Patricia Gerdes, Seth W. Cheetham, Stephanie N. Schauer, Prabha Ajjikuttira, Thomas Joshua Meyer et al. · 2022 · Genome Research
AMPA receptor deletion in developing MGE-derived hippocampal interneurons causes a redistribution of excitatory synapses and attenuates postnatal network oscillatory activity
Gülcan Akgül, Chris J. McBain · 2020 · Scientific Reports
DEPDC5 takes a second hit in familial focal epilepsy
Matthew P. Anderson · 2018 · Journal of Clinical Investigation
Samovar: Single-Sample Mosaic Single-Nucleotide Variant Calling with Linked Reads
Charlotte A. Darby, James Fitch, Patrick Joseph Brennan, Benjamin Kelly, Natalie Bir, Vincent J. Magrini, Jeffrey Leonard, Catherine E. Cottrell, Julie M. Gastier, Richard K. Wilson et al. · 2019 · iScience
Somatic copy number variants in neuropsychiatric disorders
Eduardo A. Maury, Christopher A. Walsh · 2021 · Current Opinion in Genetics & Development
Comprehensive identification of somatic nucleotide variants in human brain tissue
Yifan Wang, Taejeong Bae, Jeremy Thorpe, Maxwell A. Sherman, Attila Jones, Sean Cho, Kenneth Daily, Yanmei Dou, Javier Ganz, Alon Galor et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
Cytogenomic landscape of the human brain
Ivan Yu. Iourov, Svetlana G. Vorsanova, Yuri B. Yurov · 2021 · Elsevier eBooks
Omics Approaches to Investigate the Pathogenesis of Suicide
Maura Boldrini, Yang Xiao, Tarjinder Singh, Chenxu Zhu, Mbemba Jabbi, Harry Pantazopoulos, Gamze Gürsoy, Keri Martinowich, Giovanna Punzi, Eric J. Vallender et al. · 2024 · Biological Psychiatry
Postzygotic Somatic Mutations in the Human Brain Expand the Threshold-Liability Model of Schizophrenia
Shiva M. Singh, Christina A. Castellani, Kathleen Allen Hill · 2020 · Frontiers in Psychiatry
Expanding studies of chromosome structure and function in the era of T2T genomics
Karen H. Miga, Beth A. Sullivan · 2021 · Human Molecular Genetics
Cell population dynamics in the course of adult hippocampal neurogenesis: Remaining unknowns
Cora Olpe, S. Jessberger · 2022 · Hippocampus
Single-cell analysis of diversity in human stem cell-derived neurons
Lise J. Harbom, Nadine Michel, Michael J. McConnell · 2017 · Cell and Tissue Research
Suppression of DNA Double-Strand Break Formation by DNA Polymerase β in Active DNA Demethylation Is Required for Development of Hippocampal Pyramidal Neurons
Akiko Uyeda, Kohei Onishi, Teruyoshi Hirayama, Satoko Hattori, Tsuyoshi Miyakawa, Takeshi Yagi, Nobuhiko Yamamoto, Noriyuki Sugo · 2020 · Journal of Neuroscience
Genomic Indexing by Somatic Gene Recombination of mRNA/ncRNA – Does It Play a Role in Genomic Mosaicism, Memory Formation, and Alzheimer’s Disease?
Uwe Ueberham, Thomas Arendt · 2020 · Frontiers in Genetics
Establishment of reference standards for multifaceted mosaic variant analysis
Yoo-Jin Jiny Ha, Myung Joon Oh, Junhan Kim, Jisoo Kim, Seungseok Kang, John Dorrance Minna, Hyun Seok Kim, Sangwoo Kim · 2022 · Scientific Data
Identifying Aging and Alzheimer Disease–Associated Somatic Variations in Excitatory Neurons From the Human Frontal Cortex
Meng Zhang, Gerard A. Bouland, Henne H. Holstege, Marcel J. T. Reinders · 2023 · Neurology Genetics
Emerging Opportunities to Study Mobile Element Insertions and Their Source Elements in an Expanding Universe of Sequenced Human Genomes
Scott E. Devine · 2023 · Genes
Single-cell mosaicism analysis reveals cell-type-specific somatic mutational burden in Alzheimer’s Dementia
Kousi, Maria, Boix, Carles, Park, Yongjin P., Mathys, Hansruedi, Sledzieski, Samuel, Peng, Zhuyu, Bennett, David A., Tsai, Li-Huei, Kellis, Manolis · 2022
Genomic Mosaicism of the Brain: Origin, Impact, and Utility
Jared H. Graham, Johannes C. M. Schlachetzki, Xiaoxu Yang, Martin W. Breuss · 2023 · Neuroscience Bulletin
Epileptogenesis and drug-resistant in focal cortical dysplasias: Update on clinical, cellular, and molecular markers
Daniel Rodrigo Marinowic, Douglas Bottega Pazzin, Sofia Prates da Cunha de Azevedo, Giulia Pinzetta, João Victor Machado de Souza, Fernando Tonon Schneider, Thales Thor Ramos Previato, Fábio Jean Varella, Jaderson Costa da Costa · 2023 · Epilepsy & Behavior
Increased somatic mosaicism in autosomal and X chromosomes for suicide death
Ikuo Otsuka, Shunsuke Uchiyama, Toshiyuki Shirai, Xiaoxi Liu, Motonori Takahashi, Yoichiro Kamatani, Chikashi C. Terao, Akitoyo Hishimoto · 2024 · Molecular Psychiatry
Genomics of autism spectrum disorder: approach to therapy
Fatma Ayhan, Geneviève Konopka · 2018 · F1000Research
The Essential DNA Damage Response Complex MRN Is Dispensable for the Survival and Function of Purkinje Neurons
Mingmei Ding, Xiaobing Qing, Guangyu Zhang, Carolin Baade‐Büttner, Ralph Gruber, Haizhen Lu, David O. Ferguson, Christian Geis, Zhao‐Qi Wang, Zhong‐Wei Zhou · 2022 · Frontiers in Aging Neuroscience
Transcription-associated DNA DSBs activate p53 during hiPSC-based neurogenesis
Nadine Michel, Heather M. Raimer, Naomi D. Atkin, Umar Arshad, Reem N. Al-Humadi, Sandeep Singh, Arkadi Manukyan, Lana N. Gore, Ian E. Burbulis, Yuh‐Hwa Wang et al. · 2022 · Scientific Reports
Genomic Chaos Begets Psychiatric Disorder
Donard S. Dwyer · 2020 · Complex Psychiatry
Concomitant selenoenzyme inhibitor exposures as etiologic contributors to disease: Implications for preventative medicine
Nicholas V.C. Ralston · 2022 · Archives of Biochemistry and Biophysics
Inducing Cre-lox Recombination in Mouse Cerebral Cortex Through In Utero Electroporation
Katherine M. Bland, Zachary O. Casey, Christopher J. Handwerk, Z. Logan Holley, George S. Vidal · 2017 · Journal of Visualized Experiments
Imaging Flow Cytometry Quantifies Neural Genome Dynamics
Nadine Michel, Usnish Majumdar, Joanne A Lannigan, Michael J. McConnell · 2019 · Cytometry Part A
Natural and pathogenic protein sequence variation affecting prion-like domains within and across human proteomes
Sean M. Cascarina, Eric D. Ross · 2020 · BMC Genomics
Mapping the Complex Genetic Landscape of Human Neurons
Chen Sun, Kunal Kathuria, Sarah B. Emery, Byung-Jun Kim, Ian E. Burbulis, Joo Heon Shin, Brain Somatic Mosaicism Network, Daniel R. Weinberger, John V. Moran, Jeffrey M. Kidd et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
Oxytocin seals the blood–brain barrier, improving 22q11.2 deletion syndrome trajectories
Giulia Castellani, Mariasole Ciampoli, Arianna Benedetti, Valentina Ferretti, Gabriella Trigilio, Weronika Barcik, Marta Busnelli, Gabriella Contarini, Camilla Paolini, Céline Devroye et al. · 2025 · Brain
RETRACTED: Modeling Brain Somatic Mosaicism With Cerebral Organoids, Including a Note on Mutant Microglia
Bert M. Verheijen · 2019 · Frontiers in Molecular Neuroscience · Retracted
Genome Maintenance in Mammalian Stem Cells
John C. Schimenti, Rui Huang, Liangdao Li, Ryan C. James · 2022 · Annual Review of Genetics
Bioinformatic and biological avenues for understanding alcohol use disorder
Emily K. Grantham, Sean P. Farris · 2018 · Alcohol
CfDNA Measurement as a Diagnostic Tool for the Detection of Brain Somatic Mutations in Refractory Epilepsy
Sonia Mayo, Irene Gómez-Manjón, Francisco Javier Fernández‐Martínez, Ana Camacho, Francisco Martı́nez, Julián Benito‐León · 2022 · International Journal of Molecular Sciences
Pivotal Impacts of Retrotransposon Based Invasive RNAs on Evolution
Laleh Habibi, Hamzeh Salmani · 2017 · Frontiers in Microbiology
Sequencing the Human Brain at Single-Cell Resolution
Malosree Maitra, Corina Nagy, Gustavo Turecki · 2019 · Current Behavioral Neuroscience Reports
Genomic data resources of the Brain Somatic Mosaicism Network for neuropsychiatric diseases
McKinzie A. Garrison, Yeongjun Jang, Taejeong Bae, Adriana Cherskov, Sarah B. Emery, Liana Fasching, Attila Jones, John B. Moldovan, Cindy Molitor, Sirisha Pochareddy et al. · 2023 · Scientific Data
Brain somatic mutations in Alzheimer’s disease: linking genetic mosaicism to neurodegeneration
Zuguang Li, Juan Zhang, Zhiqiang Liu, Lu Yu, Chunqing Yang, Luoman Zhang, Zhigao Xiang, Feng Hu, Nadezda Brazh, Kai Shu et al. · 2025 · Molecular Neurodegeneration
Somatic CNV Detection by Single-Cell Whole-Genome Sequencing in Postmortem Human Brain
Diego Pérez‐Rodríguez, Maria Kalyva, Catherine Santucci, Christos Proukakis · 2022 · Methods in molecular biology
Genomic variation in neurons
Sunjidmaa Zolzaya, Ayano Narumoto, Yu Katsuyama · 2023 · Development Growth & Differentiation
Adaptive and Maladaptive DNA Breaks in Neuronal Physiology and Alzheimer’s Disease
Anysja Roberts, Russell Howard Swerdlow, Ning Wang · 2024 · International Journal of Molecular Sciences
Primate-specific retrotransposons and the evolution of circadian networks in the human brain
Manci Li, Peter A. Larsen · 2021 · Neuroscience & Biobehavioral Reviews
Combined Fluorescent In Situ Hybridization (FISH) and Immunofluorescence for the Targeted Detection of Somatic Copy Number Variants in Synucleinopathies
Monica Emili Garcia‐Segura, Diego Pérez‐Rodríguez, Christos Proukakis · 2022 · Neuromethods
Rats Selected for Different Nervous Excitability: Long-Term Emotional–Painful Stress Affects the Dynamics of DNA Damage in Cells of Several Brain Areas
Veronika Shcherbinina, M. B. Pavlova, Е. В. Даев, Natalia A. Dyuzhikova · 2024 · International Journal of Molecular Sciences
A screen of brain organoids to study neurodevelopmental disease
Adriana Cherskov, Nenad Šestan · 2020 · Nature
Somatic mutations in single human cardiomyocytes demonstrate accelerated age-related DNA damage and cell fusion
Christopher A. Walsh, Sangita Choudhury, August Yue Huang, Junho Junho Kim, Katherine S. Morillo, Eduardo A. Maury, Zinan Zhou, Connor J. Kenny, Eunjung Lee, Ming Hui Chen · 2020 · Research Square
Somatic mutations reveal hypermutable brains and are associated with neuropsychiatric disorders
Taejeong Bae, Liana Fasching, Yifan Wang, Joo Heon Shin, Milovan Šuvakov, Yeongjun Jang, Scott Norton, Caroline Dias, Jessica Mariani, Alexandre Jourdon et al. · 2022 · medRxiv
LINE-1 retrotransposon activation intrinsic to interneuron development
Gabriela Oana Bodea, Juan Manuel Botto, Maria E. Ferreiro, Francisco Jose Sanchez-Luque, Jose de los Rios Barreda, Jay Rasmussen, Muhammed A. Rahman, Laura R. Fenlon, Natasha Jansz, Carolina Gubert et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
Ras, RhoA, and vascular pharmacology in neurodevelopment and aging
Ruth Nussinov, Hyunbum Jang, Feixiong Cheng · 2024 · Neurochemistry International
From cytogenetics to proteogenomics: new horizons in the study of aneuploidies
Kira S. Zadesenets, Н. Б. Рубцов · 2025 · Vavilov Journal of Genetics and Breeding
Cancer-causing somatic mutations: they are neither necessary nor sufficient
Carlos Sonnenschein, Ana Maria Soto · 2018 · Organisms. Journal of Biological Sciences
Understanding the epigenetic architecture of psychiatric disorders: Modifications and beyond
Kazuya Iwamoto · 2018 · Psychiatry and Clinical Neurosciences
Evidence that APP gene copy number changes reflect recombinant vector contamination
Junho Kim, Boxun Zhao, August Yue Huang, Michael B. Miller, Michael A. Lodato, Christopher A. Walsh, Eunjung Alice Lee · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
Confined migration induces non-lethal DNA damage in developing neurons
Zhejing Zhang, Andrés Canela, Junko Kurisu, Peilin Zou, Takumi Kawaue, Naotaka Nakazawa, Noriko Takeda, Mai Saeki, Maki Utsunomiya, Merve Bilgic et al. · 2026 · Nature
Somatic genomic mosaicism in the brain during aging: Scratching the surface
Taejeong Bae, Yifan Wang, Flora Maria Vaccarino, Alexej S. Abyzov · 2022 · Clinical and Translational Medicine
A Unifying Hypothesis for the Genome Dynamics Proposed to Underlie Neuropsychiatric Phenotypes
George Sebastian Gericke · 2024 · Genes
Fire & Language: The Two-Faced Process of Progress in Deep-Structural Sociocultural Evolution
Jan-Boje Frauen · 2020 · World Futures
Identifying aging and Alzheimer's disease associated somatic mutations in excitatory neurons from the human frontal cortex using whole genome sequencing and single cell RNA sequencing data
Meng Zhang, Gerard A. Bouland, H. Holstege, M. Reinders · 2022 · medRxiv
A microglia clonal inflammatory disorder in Alzheimer’s Disease
Rocío Vicario, Stamatina Fragkogianni, Leslie Weber, Tomi Lazarov, Yang Hu, Samantha Y. Hayashi, Barbara P. Craddock, Nicholas D. Socci, Araitz Alberdi, Ann Baako et al. · 2024 · eLife
Perinatal elimination of genetically aberrant human cortical neurons
Diane D. Shao, Yifan Zhao, Joseph Brew, Yahia Adla, Urmi Ghosh, Vinay Viswanadham, Lovelace J. Luquette, Sijing Zhao, Andrea J. Kriz, Xuyu Qian et al. · 2026 · Nature