The DOI matches its Crossref record; 105 of the 105 references it cites were found in a registry or an index.
Southern African ancient genomes estimate modern human divergence to 350,000 to 260,000 years ago
Abstract
Ancient DNA pushes human emergence back: Anatomically modern humans evolved in Africa, but pinpointing when has been difficult. Schlebusch et al. sequenced three ancient African genomes from the Stone Age, about 2000 years old, and four from the Iron Age, 300 to 500 years old. One of the oldest samples, sequenced to 13× coverage, appears most closely to resemble individuals from the present-day San population. However, this individual seems to have lacked genetic contributions from other modern African populations, including pastoralists and farmers, which were observed in modern San individuals. Thus, the earliest divergence between human populations may have occurred 350,000 to 260,000 years ago. Science , this issue p. 652
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“These Neanderthal haplotype blocks may have originated in ancient European migrants to eastern Africa (26) and spread beyond eastern Africa through gene flow, which is known to have affected even the basal Africa-MBK lineages (27).”
From An ancestral recombination graph of human, Neanderthal, and Denisovan genomes (2021) · cites this paper as [27]
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“These observations suggest that the population-specific haplotype blocks may be the result of more recent population-specific Neanderthal admixture, as has recently been suggested (26–28, 30).”
From An ancestral recombination graph of human, Neanderthal, and Denisovan genomes (2021) · cites this paper as [27]
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Metadata
- Authors
- Schlebusch, C. M., Malmström, H., Günther, T., Sjödin, P., Coutinho, A., Edlund, H., Munters, A. R., Vicente, M., Steyn, M., Soodyall, H., Lombard, M., & Jakobsson, M.
- Affiliations
- Uppsala University (SE)
- University of the Witwatersrand (ZA)
- National Health Laboratory Service (ZA)
- University of Johannesburg (ZA)
- Corresponding author
- Schlebusch, Carina M.
- Malmström, Helena
- Lombard, Marlize
- Jakobsson, Mattias
- ORCID
- Venue
- Science
- Published
- 2017-11-03
- Volume
- 358
- Issue
- 6363
- Pages
- 652-655
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2760172958
- Cited by
- 519
- References
- 105
- Citations by year
- 2026: 23 · 2025: 71 · 2024: 48 · 2023: 57 · 2022: 46 · 2021: 94 · 2020: 49 · 2019: 53 · 2018: 71 · 2017: 7
- FWCI
- 32.68
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Science (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Wenner-Gren Foundation (award344363)
- Göran Gustafssons Stiftelse för Naturvetenskaplig och Medicinsk Forskning (award344362)
- Knut och Alice Wallenbergs Stiftelse (award344359)
- Vetenskapsrådet (award344360, 642-2013-8019, award344361, 621-2014-5211)
- South African National Research Foundation (award344364)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Forensic and Genetic Research
- Social Sciences › Anthropology › Pleistocene-Era Hominins and Archaeology
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic diversity and population structure
- Keywords
- ancient human genomes, Bantu population, genetic admixture, KwaZulu-Natal, Southern Africa
- MeSH terms
- DNA, Ancient, Biological Evolution, Humans, South Africa, Genetic Variation, Genome, Human, Black People
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