Precision medicine using microbiota
Abstract
Intestinal microbiota influence cancer patient responses to immunotherapy
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Patient stratification on the basis of gut microbiome composition may be important to identify responders and nonresponders to immunotherapy for the treatment of epithelial tumors and melanomas.
“recent studies confirm the potential importance of patient stratification on the basis of gut microbiome composition to identify responders and nonresponders to immunotherapy for the treatment of epithelial tumors and melanomas (Gopalakrishnan et al., 2018;Jobin, 2018;Routy et al., 2018)”
From Gut reactions: Breaking down xenobiotic–microbiome interactions (2019) · cites this paper as Jobin, 2018
Recent observations indicate the importance of gut microbiome composition and the response to cancer therapeutic drugs.
“We can take encouragement in these efforts from recent observations regarding the importance of gut microbiome composition and the response to cancer therapeutic drugs (Jobin, 2018).”
From Gut reactions: Breaking down xenobiotic–microbiome interactions (2019) · cites this paper as Jobin, 2018
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References 15 · Cited by 133
- Authors
- Jobin, C.
- Affiliations
- University of Florida (US)
- Corresponding author
- Jobin, Christian
- ORCID
- Jobin, Christian
- Venue
- Science
- Published
- 2018-01-05
- Volume
- 359
- Issue
- 6371
- Pages
- 32-34
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2782277684
- Cited by
- 133
- References
- 15
- Citations by year
- 2026: 5 · 2025: 10 · 2024: 10 · 2023: 19 · 2022: 10 · 2021: 12 · 2020: 25 · 2019: 23 · 2018: 19
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Science (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Diabetes and Digestive and Kidney Diseases (R01DK073338)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Health Sciences › Medicine › Oncology › Cancer Immunotherapy and Biomarkers
- Health Sciences › Medicine › Oncology › Colorectal Cancer Treatments and Studies
- Keywords
- gut microbiota, cancer immunotherapy, immunotherapy response, precision medicine
- MeSH terms
- Humans, Precision Medicine, Microbiota
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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