An evolution-based model for designing chorismate mutase enzymes

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Items 201–300 of 314

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10. Evolutionary Probability and Stacked Regressions Enable Data-Driven Protein Engineering with Minimized Experimental Effort
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12. Design of a Protein with Improved Thermal Stability by an Evolution‐Based Generative Model
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17. Identification of coevolving positions by ancestral reconstruction
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18. PRO‐LDM: A Conditional Latent Diffusion Model for Protein Sequence Design and Functional Optimization
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19. Considering Metabolic Context in Enzyme Evolution and Design
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20. Exploring evolutionary trajectories of drug resistance
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21. A Comprehensive Review of Transformer-Based Language Models for Protein Sequence Analysis and Design
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22. Origins and breadth of pairwise epistasis in an α-helix of β-lactamase TEM-1
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28. Disentanglement of Evolutionary Constraints in Statistical Models of Proteins
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29. Expanding the space of self-reproducing ribozymes using probabilistic generative models
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30. ProFam: Open-Source Protein Family Language Modelling for Fitness Prediction and Design
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31. Determinants of metal import and specificity in a bacterial transporter
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32. Introduction to Bayesian inference
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33. Impact of phylogeny on the inference of functional sectors from protein sequence data
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34. Generative Modeling of RNA Sequence Families with Restricted Boltzmann Machines
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42. A Generative Neuro‐Symbolic AI for Protein Sequence Design
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44. Hallucinating functional protein sequences
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45. Ancestral terpene cyclases: From fundamental science to applications in biosynthesis
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46. Epistasis Creates Invariant Sites and Modulates the Rate of Molecular Evolution
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47. Disentanglement of Entropy and Coevolution using Spectral Regularization
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48. Co-evolution integrated deep learning framework for variants generation and fitness prediction
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49. Learning to Read and Write in the Language of Proteins
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50. NeuroFold: A Multimodal Approach to Generating Novel Protein Variants in silico
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51. From Scarce Functional Labels to Label-Aware Generation in Homologous Protein Families
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52. Design and experimental characterization of specificity-switching mutational paths of WW domains
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53. Modeling Protein Evolution via Generative Inference From Monte Carlo Chains to Population Genetics
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54. High Diversity Gene Libraries Facilitate Machine Learning Guided Exploration of Fluorescent Protein Sequence Space
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55. From genes to collective modes: biological constraints shape metabolic evolution
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56. Out-of-Equilibrium Selection Pressure Enhances Inference from Protein Sequence Data
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57. A Macro-scale Comparison Algorithm for Analysis of TCR Repertoire Completeness
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58. Peer Review #1 of "Navigating the amino acid sequence space between functional proteins using a deep learning framework (v0.1)"
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59. Peer Review #2 of "Navigating the amino acid sequence space between functional proteins using a deep learning framework (v0.1)"
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60. Sequence Grammar Underlying Unfolding and Phase Separation of Globular Proteins
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62. Supervised learning: classification with neural networks
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63. Preface
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64. Copyrigt Page
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65. Asymptotic inference and information
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66. Priors, regularisation, sparsity
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67. Time series: from Markov models to hidden Markov models
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68. High-dimensional inference: searching for principal components
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69. Graphical models: from network reconstruction to Boltzmann machines
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77. Functionally Important Residues from Graph Analysis of Coevolved Dynamic couplings
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78. Functionally Important Residues from Graph Analysis of Coevolved Dynamic couplings
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