p21 produces a bioactive secretome that places stressed cells under immunosurveillance

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Items 201–298 of 298

1. Cellular Senescence in Cancer: Mechanisms, Roles in Tumor Progression, and Therapeutic Implications
   Jingrui Yan, Yu Zhang, Guohua Mao, Jun Yu, Tianxing Zhou, Jihui Hao · 2025 · MedComm – Oncology
2. Communication breakdown: senescent cells in interorgan communication of aging
   Rituparna Banik Ghosh, Shweta S. Dipali, Gabriela Desdín-Micó, Matthew J. Yousefzadeh · 2026 · Trends in Endocrinology and Metabolism
3. Immunological consequences of senescence in physiology and pathology
   Anastasija Zubova, Federico Pietrocola, Samir Morsli · 2026 · Journal of Translational Medicine
4. Disruption of CDK4/6–RARα–NF-κB axis attenuates senescence-associated inflammation and improves function during aging and following chemotherapy
   Boshi Wang, Alessio Piccolantonio, Abdullah Altulea, Mengling Huang, Trupthi Joshi, Francesca Pagliarin, Michele Di Palma, Yao Lin, Sebastian J. Mackedenski, Kirill Ustyantsev et al. · 2026 · Nature Aging
5. Differential Effects of Biomimetic Thymine Dimers and Corresponding Photo-Adducts in Primary Human Keratinocytes and Fibroblasts
   Rosanna Monetta, Denise Campagna, Valeria Bartolocci, Alessio Capone, Massimo Teson, Silvia Filippi, Sofia Gabellone, Davide Piccinino, Raffaele Saladino, Elena Dellambra · 2024 · Biomolecules
6. Senescence in human AC16 cardiac cells is associated with thymidine kinase induction and histone loss
   Nikhitha Kastury, Veronica Hidalgo, Boomathi Pandi, Lauren Li, Maggie P. Y. Lam, Edward Lau · 2023 · PubMed Central
7. Healthy aging—would cytotoxic T lymphocytes stand out?
   Tianyu Zhang, Jinjin Zhang, Shixuan Wang · 2023 · Cell Death Discovery
8. An Integration of RNA Sequencing and Network Pharmacology Approaches Predicts the Molecular Mechanisms of the Huo-Xue-Shen Formula in the Treatment of Liver Fibrosis
   Keying Jiang, Jianfeng Bao, Zhonghan Lou, Fei Liu, Keyang Xu, Hiu Yee Kwan · 2025 · Pharmaceuticals
9. Discovery of Benzodiazepine-Based Inhibitors of the E2 Enzyme UBCH10 from a Cell-Based p21 Degradation Screen
   Benoit Pelletier, Stéphanie Duhamel, Guillaume Tambutet, Scott Jarvis, Patrick Cléroux, Maud David, Pierre‐Luc Tanguay, Laure Voisin, Clint A. James, Rico Lavoie et al. · 2023 · ACS Chemical Biology
10. The role of senescence in cancer therapy-associated cardiovascular toxicity
    Yasmin K. Alshoubaki, Vivienne Grüterich, Valentina Zollet, Gabriela M. Kuster · 2024 · The Journal of Cardiovascular Aging
11. Epigenetic dynamics of cellular senescence: From mechanistic insights to precision senotherapy
    Xiangjun Hu, Weijing Lai, Mengyuan Liu, Bo Wang · 2026 · Chinese Medical Journal
12. Genome-wide CRISPR/Cas9 screen identified MCL1 as a senolytic target for clearing palbociclib-induced senescent and PD-L1-positive cells in colorectal cancer
    Hao Wang, Tianqi Shen, Suisui Yang, Xiaohui Zhou, Pingping Cao, H Yu, Kexin He, Min Fu, H Yu, Xiaorong Liu et al. · 2026 · Cancer Letters
13. The immunology behind inflammaging—causes, sources, and mechanisms
    Ines Sturmlechner, Nathan K. LeBrasseur, Cornelia M. Weyand, Jörg J. Goronzy · 2026 · Journal of Allergy and Clinical Immunology
14. Senotypes define the diverse landscape of senescent cells
    Marissa J. Schafer, Nathan Basisty, Ann Vogel Hertzel, Alexandra N. Rindone, Jennifer H. Elisseeff, Vidyani Suryadevara, Constantin Aliferis, Paul D. Robbins, Laura J. Niedernhofer, Karl N. Miller et al. · 2026 · Nature Aging
15. CRISPR screens identify targets to rescue age-related T cell dysfunction in cancer
    Alex C.Y. Chen, Keely Y. Ji, Cansu Yerinde, Nelson H. Knudsen, Kevin Bi, Shumeng Hao, Vasyl Zhabotynsky, Daniela Martinez, Thomas James LaSalle, Kazuhiro Taguchi et al. · 2026 · Cell
16. Immune surveillance and immune evasion of senescent cells
    Pau Garcia-Baucells, Manuel Serrano, Corina Amor · 2026 · Nature reviews. Immunology
17. Inflammatory β-Cell Stress and Immune Surveillance in Type 1 Diabetes
    Anil Bhushan, Peter J. Thompson · 2024 · Cold Spring Harbor Perspectives in Medicine
18. Early Neutrophil Sensing Shapes the Innate Response to Preneoplastic Mammary Cells
    Antoine Debiesse, Manuela Pereira-Abrantes, Lyvia Moudombi, Aurélien Voissière, Leïla Lefèvre, Pacôme Lecot, Céline Rodriguez, Marine Malfroy, Iryna Moskalevska, Hélène Vanacker et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
19. BRCA mutation alters the stromal landscape in normal ovaries
    Het T. Vaishnav, Alyssa Murray, Olivia R. Piccolo, Curtis W. McCloskey, Edward Yakubovich, Elizabeth A. Macdonald, Maryam Echaibi, Manon de Ladurantaye, Euihye Jung, Thomas J. Fazio et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
20. Senescent CD8 T effector memory cells are functionally impaired, enriched in aging and disease, and a barrier to immunotherapy
    Paolo S. Turano, Elizabeth Akbulut, Nica M. Aquino, Luis Garza-Martínez, Sukhwinder Singh, Abraham Aviv, Simon Toupance, George S. Yap, Patricia Fitzgerald-Bocarsly, Ricardo I. Martínez-Zamudio et al. · 2026 · Proceedings of the National Academy of Sciences
21. Elimination of senescent cells by mechanical cell competition
    Yuping Pan, Mattheus Xing Rong Foo, Vinod S O Prabhakaran, Kashish Jain, Pakorn Kanchanawong, Oliver Dreesen, Yusuke Toyama · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
22. Early senescence of pancreatic β cells induced by unfolded protein response deficiency prevents type 1 diabetes
    Haipeng Cheng, Zhen-Wang Zhao, Dan Liu, Yufei Wang, Min Zhang · 2024 · Journal of Zhejiang University SCIENCE B
23. LIMA1 Is a Prognostic Senescence‐Inhibitory Gene in Head and Neck Squamous Carcinoma
    Yuanhe You, Zhong Du, Zhuowei Tian, Fan Yu, Shunshun Li, Jie He, Meng Xiao, Yanan Wang · 2025 · Oral Diseases
24. Novel kinetic and developmental transcriptomic pan-stress responses by embryonic stem cells
    Aditi Singh, Ximena Lu Ruden, Wen Tang, Awoniyi Olumide Awonuga, Douglas Mark Ruden, Steven J. Korzeniewski, Elizabeth Ella Puscheck, Hao Feng, Daniel Allen Rappolee · 2025 · Scientific Reports
25. Exploring the uncharted role of cell senescence in rare diseases
    Piera Selvaggio, Esi Taci, Alessandra Barassi, Valentina Massa, Cristina Gervasini, Elena A. Lesma, Clara Bernardelli, Elisabetta Di Fede · 2025 · Orphanet Journal of Rare Diseases
26. Identification of Core SASP-Related Genes TGFBI and ANXA6 for Diagnosing Ulcerative Colitis-Related Colorectal Cancer Through Machine Learning
    Jukun Zhang, Ping Wang, Siqi Yuan, Yingjian Zhang · 2025 · Journal of Inflammation Research
27. The Pathogenic Role of the DNA Double-Stranded Breaks in Hereditary Cardiomyopathies
    Ali J. Marian · 2025 · Heart Failure Clinics
28. Anti-Müllerian hormone induces a reversible quiescence-associated secretory phenotype in preantral follicles
    Marie-Charlotte Meinsohn, Josephine Cleverdon, Alana M. Mermin-Bunnell, Karine de Mattos, Phoebe May, Aki Kashiwagi, Rhian G Stavely, Nicholas G. Nagykery, Diane C. Saunders, Elizabeth L. Tsui et al. · 2025 · Biology of Reproduction
29. Targeting cellular senescence in progenitor cells as a strategy to enhance bone regeneration by cell therapies: a systematic review of pre-clinical investigations
    Mayu Morita, Eshan B. Damle, Issei Shinohara, Masatoshi Murayama, Yosuke Susuki, Qi Gao, Chao Ma, Simon Kwoon‐Ho Chow, Stuart Barry Goodman · 2025 · Stem Cell Research & Therapy
30. Identification and validation of key PANoptosis-related genes via integrative machine learning and single-cell sequencing in AILI
    Shuo Li, Chenhui He, Meng Wang, Binli Ran, Guanghui Li, Guangzhong Dong, Heng Zhang, Chaopeng Mei, Yaodong Song, Qiwen Yu et al. · 2026 · iScience
31. Spatial and single-cell transcriptomics reveals senescence-associated changes in MIA-induced ASD male mouse brain
    Wei Zhang, Kaizhao Chen, Yue Ke, Dejun Yan, Ziyang Lin, Longjun Chen, Ziqing Gao, Yuke Shen, Haoyang Wan, Xi Yang et al. · 2026 · Cell Reports
32. Beyond binary senescence: Intermediate cellular states, tissue distribution, and therapeutic implications in ageing
    Soon Sang Park, June Heo, Hee Young Kang, Tae Jun Park · 2026 · Ageing Research Reviews
33. p16 Beyond Senescence: Cancer Biology Lessons Applied to Endometriosis
    Hiroshi Kobayashi · 2026 · Reproductive Sciences
34. SenFlag gene signature identifies senescent cells in mouse and human tissues through a conserved core transcriptional program
    Abdullah Altulea, Sebastian J. Mackedenski, Jamil Nehme, Marco Demaria · 2026 · The EMBO Journal
35. MDM2 deletion and its associated p53 activation in subcutaneous white adipose tissue induce hepatic fibrosis via galectin-3 in a mouse model
    Pujie LIU, Kekao Long, Yi Wang, Jordy Evan Sulaiman, Baomin Wang, Xiangyu ZHOU, Chang Liu, Yating CHENG, Yin Cai, Huating Li et al. · 2026 · Metabolism
36. Elevated neutrophil extracellular traps formation driven by the HPV-mediated CXCL8-CXCR1/2-ROS-p21 axis promotes the growth and metastasis of cervical cancer
    Xin Wang, Alimire Julaiti, Aikelimu Aisikaer, Hongjian Wei, Runda Jie, Xinyan Liu, Yonghua Shi · 2026 · Frontiers in Immunology
37. Clinicopathological significance and prognostic analysis of p21 and EGFR in colorectal cancer: a retrospective analysis on 12 319 cases in China
    Yang Fei, Mengke Ma, Lu Gan, Midie Xu, Yang Yu, Dan Ai Huang, Weiqi Sheng · 2024 · Journal of Clinical Pathology
38. Senescence and the Microenvironment
    Mohit Kumar Rai, Pallavi Yadav, Arjun S. Katailiha, Aloukick Kumar Singh, Sandeep Kumar Yadav · 2025 · Springer eBooks
39. Chidamide Accelerates the Death of Senescence‐Like Diffuse Large B‐Cell Lymphoma Cells With TP53 Mutation Induced by Doxorubicin
    Yun‐yan Yin, Yu Liu, Yi‐qi Lu, Zhi‐meng Tang, Zheng‐xin Zhu, Mengyuan Zhu, Hongyu Chen, Hui Hui, Jingyan Xu, Hui Li · 2025 · The FASEB Journal
40. Kisspeptins and norepinephrine regulate different G-protein-coupled receptor signaling pathways
    Rafael Rosell, María González‐Cao, Masaoki Ito, Mireia Marco Jordan, José Luis Gómez-Vázquez, Jinghua Chen, Andrés Aguilar, Imane CHAIB-OUKADOUR · 2022 · Translational Lung Cancer Research
41. Role of Senescence-Resumed Proliferation in Keloid Pathogenesis
    Ching‐Yun Wang, Chieh-Wen Wu, Ting-Yi Lin · 2023 · Future Pharmacology
42. Clearing stressed cells
    Virinder Reen, Jesús Gil · 2021 · Science
43. Transfer learning of an in vivo- derived senescence signature identifies conserved and tissue-specific senescence across species and diverse pathologies
    Christopher Cherry, James I. Andorko, Kavita Krishnan, Joscelyn C. Mejías, Helen Hieu Nguyen, Katlin B. Stivers, Elise F. Gray-Gaillard, Anna Ruta, Naomi Hamada, Masakazu Hamada et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
44. Identification of molecular diagnostic markers in sepsis-induced acute lung injury
    Yingying Huang, Jiameng Chen, Wenjie Li, Shaowei Jiang, Yuxin Leng, Chengjin Gao · 2023 · Preprints.org
45. Linked regulation of genome integrity and senescence-associated inflammation by p53
    Karl N. Miller, Brightany Li, Hannah R. Pierce-Hoffman, Shreeya Patel, Xue Lei, Adarsh Rajesh, Marcos G. Teneche, Aaron P. Havas, Armin Gandhi, Carolina Cano Macip et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
46. The Fundamental Cause of Neurodegenerative Diseases
    Bilu Huang · 2025 · SSRN Electronic Journal
47. Zinc-based treatment of atopic dermatitis and other skin diseases
    О.В. Кандалова, Ключникова Дина Евгеньевна, И.В. Елистратова · 2022 · Nauchno-prakticheskii zhurnal «Patogenez»
48. Transfer learning identifies in vivo senescence heterogeneity and contributions to vascularization and matrix production across species and diverse pathologies
    Christopher Cherry, James I. Andorko, Kavita Krishnan, Joscelyn C. Mejías, Helen Hieu Nguyen, Katlin B. Stivers, Elise F. Gray-Gaillard, Anna Ruta, Jin Han, Naomi Hamada et al. · 2022 · Research Square
49. Typhoid toxin hijacks Wnt5a to potentiate TGFβ-mediated senescence and Salmonella infections
    Mohamed ElGhazaly, Mark O. Collins, Angela EM Ibler, Daniel Humphreys · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
50. Senolysis through thrombomodulation
    Corey M. Webster, Jan M. van Deursen · 2023 · Cell Research
51. TRAIL pathway suppression of cancer cell growth and immune cell-mediated tumor cell-killing in a senescent fibroblast-constructed tumor microenvironment
    Shengliang Zhang, Kelsey E. Huntington, Lanlan Zhou, Attila A. Seyhan, Bianca Kun, Benedito A. Carneiro, Jill A. Kreiling, John M. Sedivy, Wafik S. El‐Deiry · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
52. SENEX-mediated CDK4/6 inhibition promotes senescence and confers apoptosis resistance in B-cell non-Hodgkin lymphoma
    JIYU WANG, Liuying Yi, KEKE HUANG, Yangyang Wang, HUIPING WANG, Zhimin Zhai · 2024 · Biocell
53. The chromatin accessibility and transcriptomic landscape of the aging mice cochlea and the identification of potential functional super-enhancers in age-related hearing loss
    Chanyuan Zhang, Ting Yang, Xiaoqin Luo, Xiaoqing Zhou, Menglong Feng, Wei Yuan · 2024 · Research Square
54. Additional file 2 of The landscape of human tissue and cell type specific expression and co-regulation of senescence genes
    Peng Xu, Minghui Wang, Won‐Min Song, Qian Wang, Guo‐Cheng Yuan, Peter H. Sudmant, Habil Zare, Zhidong Tu, Miranda E. Orr, Bin Zhang · 2022 · Figshare
55. Integrative analysis based on the cell cycle-related genes identifies TPX2 as a novel prognostic biomarker associated with tumor immunity in breast cancer
    Xinli Liu, Wenyi Wang, Bing Chen, Shengjie Wang · 2024 · Aging
56. Tumor suppressor p73 transcriptionally regulates c-FLIP to impede its priming of extrinsic apoptosis while a “switcher compound” degrades c-FLIP protein
    Shengliang Zhang, Lanlan Zhou, Wafik S. El‐Deiry · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
57. TERT prevents obesity-induced metabolic disorders by promoting adipose stem cell expansion and differentiation
    Laura Braud, Manuel Bernabe, Julien Vernerey, Antonio M. A. Miranda, Andrea Dominguez, Dmitri Churikov, Manon Richaud, Liam McAllan, Christophe Lachaud, Jesús Gil et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
58. A human and mouse subpopulation of senescent β-cells induces pathologic dysfunction through targetable paracrine signaling
    Kanako Iwasaki, Priscila Carapeto, Cristian Abarca, Francesko Hela, Stephanie Sanjines, Sebastian Pena, Sandra M. Le, Hui Pan, Christopher Cahill, Ayush D. Midha et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
59. Cerebrovascular p16INK4A expression induces cerebral small vessel disease-related phenotypes
    Keiji Kawatani, Tomonori Aikawa, Zeynab Tabrizi, Yining Pan, Yingxue Ren, Ni Wang, Aishe Kurti, Toshihiko Nambara, Clark C Ikezu, Francis Shue et al. · 2025 · Acta Neuropathologica Communications
60. The dual role of cellular senescence in tumor occurrence and development
    Xiaoshan Huang, Zi-Rui Wang, Buling Wu, Wen-wei Song · 2025 · Discover Medicine
61. Additional file 1 of The landscape of human tissue and cell type specific expression and co-regulation of senescence genes
    Xu, Peng, Wang, Minghui, Song, Won-min, Qian Wang, Guo‐Cheng Yuan, Peter H. Sudmant, Habil Zare, Zhidong Tu, Miranda E. Orr, Zhang, Bin · 2022 · Figshare
62. Additional file 2 of The chromatin accessibility and transcriptomic landscape of the aging mice cochlea and the identification of potential functional super-enhancers in age-related hearing loss
    Chanyuan Zhang, Ting Yang, Luo, Xiaoqin, Xiaoqing Zhou, Menglong Feng, Wei Yuan · 2024 · Figshare
63. Additional file 1 of The chromatin accessibility and transcriptomic landscape of the aging mice cochlea and the identification of potential functional super-enhancers in age-related hearing loss
    Chanyuan Zhang, Ting Yang, Luo, Xiaoqin, Xiaoqing Zhou, Menglong Feng, Wei Yuan · 2024 · Figshare
64. Pathogenetic markers of cellular senescence
    Yuliya V. Markina, Tatiana Vladimirovna Kirichenko, Ivan V. Zhivodernikov, Alexander M. Markin, Ilya Igorevich Eremin, Roman V. Deev, Konstantin Valentinovich Kotenko · 2025 · I P Pavlov Russian Medical Biological Herald
65. Age-associated Autoimmunity Driven by T cell Immunosenescence
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66. Glycine ameliorates aging-related dysfunctions associated with Nmdmc-mediated mitochondrial one-carbon metabolism
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67. Multi-omic analysis of the liver-breast axis reveals key hepatic mediators of breast cancer progression
    Gao Yuanze, Fei Wang, Kumar Ganesan, Jianping Chen · 2026 · Science China Life Sciences
68. Benzo[a]pyrene induces keratinocyte senescence and p21-dependent differentiation
    Daniel Cheng Lui Law, Melissa Li Fang Tang, Maurice A. M. Van Steensel · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
69. Bioadhesive Hydrogel With Polyphenol‐Armored Nanogene Rejuvenates Chondrocyte Senescence for Aged Osteoarthritis Therapy
    Liwei Yan, Runze Yang, Ting Zhou, Tianhao Xu, Yongqi Li, Yuelin Hu, Minghao Ge, Li Zhang, Xiong Lu, Chaoming Xie et al. · 2026 · Advanced Science
70. Beyond survival: What drives senescence in trauma, shock and sepsis?
    Martin Mösenlechner, Anita A. Ignatius, Melanie Haffner‐Luntzer, Rebecca Halbgebauer, Markus Stefan Huber-Lang · 2026 · Injury
71. PRMT6 inhibition or deficiency attenuates diabetic neuropathic pain in male mice and is associated with reduced spinal neuroinflammation, microgliosis, and altered p53-p21 signaling
    Yan Chu, Honghao Song, Mengqiu Deng, Yuanyuan Fang, Ruifeng Ding, Kesheng Huang, Xiaoyi Fan, Lei Peng, Yutong Yang, Huawei Wei et al. · 2026 · Journal of Neuroinflammation
72. A YAP–TEAD4–CTCF transcriptional regulatory axis associated with the elimination of injured hepatocytes from the liver
    Daiki Hatakeyama, Yoshimi Okamoto‐Uchida, Misaki Kosaka, Haruka Hirose, Satoshi Kofuji, Keiko Kanayama, Yoshiki Endo, Michiko Nakagawa, Akinori Kanai, Yutaka Suzuki et al. · 2026 · Research Square
73. Modulation of JAK/STAT signaling pathway in the ovine thymus and lymph node during early pregnancy
    Chenxu Wu, Jingjing Li, Yaqi Zhang, Qianqian Shi, Leying Zhang, Ling Yang · 2026 · Veterinary Immunology and Immunopathology
74. Identification of aging-related signature genes in temporomandibular joint degeneration based on bioinformatics
    Xinyi Wang, Ziyang Xia, Y Zhou, Minda Wang, Ting Xin Jiang, Jingwen Yang · 2026 · BMC Oral Health
75. The integrated developmental stress response (ISR-DASR) shift reveals a functional transition from cellular to stem cell organismal adaptation
    Ximena Lu Ruden, Campbell Coddington, Lynessa Asplund, Awoniyi Olumide Awonuga, Douglas Mark Ruden, Steven J. Korzeniewski, Lijun Zhang, E. Puscheck, Daniel Allen Rappolee · 2026 · Scientific Reports
76. Distinct fibroblast and perivascular senotypes define spatial niches that regulate fibrosis
    Alexandra N. Rindone, Sushma Nagaraj, Anna Cho, Maria Browne, Kavita Krishnan, Ricky S. Adkins, Daniel Lesperance, Joshua Orvis, Prarthana Sanjay Daswani, Joscelyn C. Mejías et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
77. JAK/STAT signaling pathway in the spleen and liver during early pregnancy in ewes
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78. Radiation-Induced Senescence in Radiopharmaceutical Therapy: Mechanisms and Therapeutic Implications
    Marcus J. Lindsey, Reinier Hernandez · 2026 · Journal of Nuclear Medicine
79. Smoking accelerates immunosenescence in multiple sclerosis
    Meerah Khan, Ekdanai Uawithya, Joshua S Mytych, Ismail Muwenda, Megan Reidy, Robert C. Axtell, Yang Mao‐Draayer · 2026 · Frontiers in Immunology
80. Targeting p21 ‐High Senescent Kupffer Cells Nanotherapeutically Potentiates Antitumor Immunity in Advanced Hepatocellular Carcinoma with Portal Vein Tumor Thrombus
    塔娜, Shuyi Wang, Boyan Zhang, N Liu, Yingchen Han, Aoran Liu, Yan Xu, Tingsong Chen, Y Zhang, Qiuhua Luo et al. · 2026 · Advanced Science
81. Escape and evasion: when immunosurveillance of senescent cells goes wrong
    Elina Shakur, Abraham Jacobs, Rituparna Ghosh, Matthew J. Yousefzadeh · 2026 · Frontiers in Genetics
82. Fibroblast State Remodelling and Stromal Depletion Shape the Ageing Microenvironment of Human Penile Skin
    Yu Chul Yang, Honghao Yu, Pingping Lin, Hang Li, Binbin Lai · 2026 · Experimental Dermatology
83. O-GlcNAcylation in cellular senescence: From molecular insights to anti-cancer therapeutic opportunities
    Adrien Pioger, Nathalie Martin, Corinne Abbadie, Vanessa Dehennaut · 2026 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
84. MYC in Oncogenesis and Therapeutic Implications
    Na Zhang, Li Wei, Cuiping Tang, Lai Pl, Wenbin Zhong, Hua You · 2026 · MedComm
85. p21 Inhibition Rescues Radiation‐Induced Osteogenic Dysfunction and Promotes Bone Regeneration in Osteoradionecrosis of the Jaw via the Rb–Smad2/3–Runx2 Axis
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86. Repair and regeneration across the lifespan: an ontogenetic perspective
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87. Timing‐Dependent Clearance of p16‐Positive Cells Mitigates Radiation‐Induced Accelerated Aging
    Karla Valdivieso, Melanie Weigand, Daniela G. Costa, Gung Lee, Nick Pirius, Hélène Martini, Shivangi Oberai, Christina Inman, Yi Zhun Zhu, Thomas von Zglinicki et al. · 2026 · Aging Cell
88. Targeting skin aging: anti-senescent potential and key enzyme modulation of Lavandula essential oils
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89. The role of senescence in kidney ageing, injury and fibrosis
    Piotr P. Janas, Tilly Mason, David A. Ferenbach · 2026 · Nature Reviews Nephrology
90. Autologous cytokine-induced NK cells as candidate cellular senolytics: evidence, obstacles, and the experiments still needed
    Ramon E. Coronado · 2026 · GeroScience
91. Cellular senescence: six decades of discovery and reinvention
    Myrthe Klaver, Lotte S. Steeneken, Naomi Veeningen, Abdullah Altulea, Marco Demaria · 2026 · The EMBO Journal
92. Histone lactylation-upregulated CEBPB transcriptionally activates CXCL12 and p21 to modulate vascular smooth muscle cell senescence and macrophage polarization.
    Yong-Xin Han, Jia-Cheng Wang, Ru-Chen Li, Xin Shi, Hua Zhou, Mo Wang, Xue-Jun Wu, Hai Yuan · 2026 · Cellular Signalling
93. A YAP – TEAD – CTCF Transcriptional Regulatory Axis Associated With the Elimination of Injured Hepatocytes From the Liver
    Daiki Hatakeyama, Yoshimi Okamoto‐Uchida, Misaki Kosaka, Haruka Hirose, Satoshi Kofuji, Keiko Danzaki, Yoshiki Endo, Michiko Nakagawa, Akinori Kanai, Yutaka Suzuki et al. · 2026 · Genes to Cells
94. p62-Keap1-Nrf2 positive feedback loop protects against inorganic arsenic-induced senescence and EMT in alveolar type II cells
    Xinyang Guo, Xinyu Ma, Liyi Qin, Yibing Li, Xinyue Han, Meiqi Wang, Xiaoxi Wei, Shuwen Gong, Wei Su, Demin Cheng et al. · 2026 · Cellular Signalling
95. Transient upregulation of the cellular senescence driver p21/CDKN1A, but not p16/CDKN2A, after contusive spinal cord injury in young adult mice
    Benjamin R. Rood, Emily R. Hodges, Yonglin Gao, Łukasz P. Słomnicki, Christine Anne Armstrong, Kariena R. Andres, Julia H. Chariker, Eric Christian Rouchka, Sujata Saraswat Ohri, Michal Hetman · 2026 · Neurotrauma Reports
96. Cellular senescence in ageing and neurodegenerative disorders: Molecular mechanisms, biomarkers, and therapeutic strategies
    Aanchal Verma, Ahsas Goyal, Neetu Agrawal, Harlokesh Narayan Yadav · 2026 · Progress in Neuro-Psychopharmacology and Biological Psychiatry
97. CD45+ cell-enriched scRNA-seq of human breast implant fibrotic capsule
    Alexandra N. Rindone, Jennifer H. Elisseeff · 2026 · Zenodo (CERN European Organization for Nuclear Research)
98. Multilayered mechanisms driving sexual dimorphism in antitumor immunity
    Maryam Faisal, Nourhan Abdelfattah, Kyuson Yun · 2026 · Trends in Immunology