Cited by 12Health and Medical Research ImpactsPharmaceutical Economics and PolicyScience and Science Education

What if NIH had been 40% smaller?

Azoulay, Pierre, Clancy, Matthew, Li, Danielle, Sampat, Bhaven N.·2025·Science

Abstract

Replaying history with less NIH funding shows widespread impacts on drug-linked research.

Integrity signals

Registry

Crossref · 10.1126/science.aeb1564

Cites

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Recomputing p-values needs the paper’s full text.

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Claims other papers make about this one

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  • The federal funding process plays a central role in shaping the direction, diversity, and long-run impact of the US scientific enterprise and the global research landscape.

    “Thus, the federal funding process plays a central role in shaping the direction, diversity, and long-run impact of the US scientific enterprise and—given America’s scientific leadership—the global research landscape as well (3–10).”
  • Decisions about allocation of taxpayer dollars influence which scientific ideas receive support, which fields advance, and which investigators are able to initiate and sustain research programs.

    “Through competitive grant programs at agencies such as the NSF and the NIH, decisions about the allocation of taxpayer dollars influence which scientific ideas receive support, which fields advance, and which investigators are able to initiate and sustain research programs (3–10).”

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References 10 · Cited by 12

Authors
Azoulay, P., Clancy, M., Li, D., & Sampat, B. N.
Affiliations
  • National Bureau of Economic Research (US)
  • Open Philanthropy Project (US)
Venue
Science
Published
2025-09-25
Volume
389
Issue
6767
Pages
1303-1305
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W4414494532
Cited by
12
References
10
Citations by year
2026: 6 · 2025: 6
FWCI
10.99
Type
journal article
Language
en
Open access
closed
Locations
  • Science (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Health and Medical Research Impacts
  • Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Pharmaceutical Economics and Policy
  • Social Sciences › Political Science and International Relations › Science and Science Education
Keywords
NIH funding, research funding cuts, pharmaceutical industry, drug discovery, history of biomedical research
MeSH terms
Pharmaceutical Research, Financing, Government, Humans, National Institutes of Health (U.S.), Research Support as Topic, United States, Biomedical Research

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