Prolonged evolution of the human B cell response to SARS-CoV-2 infection
Sakharkar, Mrunal, Rappazzo, C. Garrett, Wieland-Alter, Wendy F., Hsieh, Ching-Lin, Wrapp, Daniel, Esterman, Emma S., Kaku, Chengzi I., Wec, Anna Z. +5 more·2021·Science Immunology
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- SARS-CoV-2 spike-reactive naïve B cells and pre-existing memory B cells contribute to antibody responses in unexposed individuals after vaccinationShishan Teng, Yabin Hu, You Wang, Yinggen Tang, Qian Wu, Xingyu Zheng, Rui Lü, Dong Pan, Fen Liu, Tianyi Xie et al. · 2024 · Frontiers in Immunology
- Characteristics and Functions of Infection-enhancing Antibodies to the N-terminal Domain of SARS-CoV-2Ruth I. Connor, Mrunal Sakharkar, Garrett Rappazzo, Chengzi I. Kaku, Nicholas C. Curtis, Seungmin Shin, Wendy Wieland‐Alter, Jordan Wentworth, Daniel W. Mielcarz, Joshua A. Weiner et al. · 2024 · Pathogens and Immunity
- Recall of pre-existing cross-reactive B cell memory following Omicron breakthrough infectionC. Kaku, Alan J. Bergeron, C. Ahlm, J. Normark, M. Sakharkar, M. Forsell, L. Walker · 2022 · bioRxiv
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- The D Gene in CDR H3 Determines a Public Class of Human Antibodies to SARS-CoV-2Meng Yuan, Ian A. Wilson · 2024 · Vaccines
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- SARS-CoV-2-Specific Memory B Cell Responses Are Maintained After Recovery from Natural Infection and PostvaccinationTom Moore, Rojony Hossain, Katie J. Doores, Manu Shankar‐Hari, David J. Fear · 2022 · Viral Immunology
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- A recurring YYDRxG pattern in broadly neutralizing antibodies to a conserved site on SARS-CoV-2, variants of concern, and related virusesHejun Liu, Chengzi I. Kaku, Ge Song, Meng Yuan, Raiees Andrabi, Dennis R. Burton, Laura M. Walker, Ian A. Wilson · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
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- Memory B cells control SARS-CoV-2 variants upon mRNA vaccination of naive and COVID-19 recovered individualsAurélien Sokal, Giovanna Barba Spaeth, Ignacio Fernández, Matteo Broketa, Imane Azzaoui, Andrea de La Selle, Alexis Vandenberghe, Slim Fourati, Anaïs Roeser, Annalisa Meola et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
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- Longitudinal analysis of SARS-CoV-2 reinfection reveals distinct kinetics and emergence of cross-neutralizing antibodies to variants of concernAntonio Facciuolo, Jill van Kessel, Andrea Kroeker, Mingmin Liao, Jocelyne M. Lew, Darryl Falzarano, Alyson A. Kelvin, Volker Gerdts, Scott Napper · 2023 · Frontiers in Microbiology
- Mechanisms Promoting Stability of B CellsVivian L. S. Kuan, Jayanta Chaudhuri · 2025 · Immunological Reviews
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- Disease Severity and Durability of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Antibody Response: A View Through the Lens of the Second Year of the PandemicLiise‐anne Pirofski · 2021 · Clinical Infectious Diseases
- Systematic analysis of human antibody response to ebolavirus glycoprotein reveals high prevalence of neutralizing public clonotypesElaine C. Chen, Pavlo Gilchuk, Seth J. Zost, Philipp A. Ilinykh, Elad Binshtein, Kai Huang, Luke Myers, Stefano R. Bonissone, Samuel Day, Chandrahaas R. Kona et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- Characterization of SARS-CoV-2 Convalescent Patients’ Serological Repertoire Reveals High Prevalence of Iso–RBD AntibodiesNicholas C. Curtis, Seungmin Shin, Andrew P. Hederman, Ruth I. Connor, Wendy Wieland‐Alter, Steven Ionov, Jennifer A. Boylston, Josh Rose, Mrunal Sakharkar, Dana B. Dorman et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- B cells imprinted by ancestral SARS-CoV-2 develop pan-sarbecovirus neutralization in immune recallsXixian Chen, Ling Li, Ruiping Du, Zuowei Wang, Yunjian Li, Yi Sun, Rongrong Qin, Hualong Feng, Lin Hu, Xuanyi Chen et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- Humoral Immune Response to Orientia tsutsugamushi Infection: Recent Research Findings and Future StudiesCasey Gonzales, Lynn Soong · 2025 · Zoonoses
- Highly efficient and low-cost single-cell culture platform for unbiased analysis of human memory B cell repertoire and antibody discoveryLuciana Conde, Debora Leite Oliveira, Gabriela Maciel, Fernando Castro, Aline Albuquerque, D. A. Rodrigues, Yare Mello, Gustavo Meira de Asis, Bárbara Gabrielle, Suyane S Ferreira et al. · 2025 · The Journal of Immunology
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- Sustained immunological memory to SARS-CoV-2 antigens. Three years of observationZulfiia E. Afridonova, А. П. Топтыгина, Elena L. Semikina · 2024 · Russian Journal of Infection and Immunity
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- COVID ‐19 Alpha Variant (B.1.1.7): Humoral, memory B and T cells in COVID ‐19 pediatric convalescentsMichael Gurevich, Rina Zilkha‐Falb, Polina Sonis, David Magalashvili, Mark Dolev, Mathilda Mandel, Shay Menascu, Anat Achiron · 2022 · Pediatric Allergy and Immunology
- Overview of the neutralizing antibody and memory B cell response kinetics in SARS-CoV-2 convalescent and/or mRNA vaccinated individuals.Irina Grigorova · 2021 · System Biology and Physiology Reports
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- Dominant and cross-reactive S1-specific memory B cell response induced by primary SARS-CoV-2 infectionXiaomin Xing, Zhaoyong Zhang, Yingfen Wen, Wenjing Guo, Xulei Zhang, Yuyi Min, Kexin Zhong, Lu Zhang, Peilan Wei, Shengnan Zhang et al. · 2025 · Scientific Reports
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- Modeling immunodominance in the B-cell response to viral infectionNikolay M. Bessonov, Gennady Alekseevich Bocharov, Daria Neverova, Vitaly A Volpert · 2023 · Mathematics and Mechanics of Complex Systems
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- Mémoire immunitaire contre le SARS-CoV-2Claude–Agnès Reynaud, Jean–Claude Weill, Pascal Chappert, Matthieu Mahévas · 2021 · médecine/sciences
- Fate and plasticity of SARS-CoV-2-specific B cells during memory and recall response in humansYves Zurbuchen, Jan Michler, Patrick Taeschler, Sarah Adamo, Carlo Cervia, Miro E. Raeber, İlhan E. Acar, Jakob Nilsson, Klaus Warnatz, Michael Soyka et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- Impacts of viral pathogenesis and vaccine immunization on the host humoral immune response in SARS-CoV-2 and associated variants of concern (VOCs) infectionSougata Roy Chowdhury, Subhendu Chakrabarty, Modhurima Chakraborti, Amlan Kumar Das · 2023 · Elsevier eBooks
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