The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Origins and Evolution of Retrotransposons
Abstract
This chapter summarizes the similarities and differences of retrotransposons, as well as the phylogenetic relationships of the various elements that have been characterized from each of the two classes of retrotransposons. It discusses what can be inferred about the ages and origins of retroelements and their relationship to other cellular components. In the most unusual group of long terminal repeat (LTR), retrotransposons, complete elements have unusual inverted or split terminal repeats and do not encode an integrase. One of the most interesting aspects of the evolution of the LTR retrotransposons is their close relationship to retroviruses, caulimoviruses, and hepadnaviruses. The simplicity of the target-primed reverse transcription (TPRT) mechanism for inserting new copies appears to permit considerable structural flexibility in the evolution of different non-LTR retrotransposons. The authors suggest that it is more likely that the LTR retrotransposons evolved from the same lineages of eubacterial sequences as all other retroelements. They have attempted in this chapter to provide an overview of the diversity and mode of evolution of eukaryotic retrotransposable elements and to trace their origins back to prokaryotic sequences.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Crystal structure at 3.5 A resolution of HIV-1 reverse transcriptase complexed with an inhibitor
Kohlstaedt, L. A., Wang, J., Friedman, J. M., Rice, P. A., & Steitz, T. A. (1992) · Science · doi:10.1126/science.1377403 · Cited by 1,914
Origin and evolution of retroelements based upon their reverse transcriptase sequences
Xiong, Y., & Eickbush, T. H. (1990) · The EMBO Journal · doi:10.1002/j.1460-2075.1990.tb07536.x · Cited by 1,374
Self-citationHuman L1 retrotransposon encodes a conserved endonuclease required for retrotransposition
Feng, Q., Moran, J. V., Kazazian, H. H., & Boeke, J. D. (1996) · Cell · doi:10.1016/s0092-8674(00)81997-2 · Cited by 1,139
Origins and evolutionary relationships of retroviruses
Doolittle, R. F., Johnson, M. S., & McClure, M. A. (1989) · The Quarterly Review of Biology · doi:10.1086/416128 · Cited by 577
Luan, D. D., & Eickbush, T. H. (1995) · Molecular and Cellular Biology · doi:10.1128/mcb.15.7.3882 · Cited by 219
Self-citationGenomic Analysis of Caenorhabditis elegans Reveals Ancient Families of Retroviral-like Elements
Bowen, N. J., & McDonald, J. F. (1999) · Genome Research · doi:10.1101/gr.9.10.924 · Cited by 102
Cited by
A Field Guide to Eukaryotic Transposable Elements
Wells, J. N., & Feschotte, C. (2020) · Annual Review of Genetics · doi:10.1146/annurev-genet-040620-022145 · Cited by 686
Widespread horizontal transfer of mitochondrial genes in flowering plants
Bergthorsson, U., Adams, K. L., Thomason, B., & Palmer, J. D. (2003) · Nature · doi:10.1038/nature01743 · Cited by 567
Volff, J. (2006) · BioEssays · doi:10.1002/bies.20452 · Cited by 419
Repetitive sequences in complex genomes: Structure and evolution
Jurka, J., Kapitonov, V. V., Kohany, O., & Jurka, M. V. (2007) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev.genom.8.080706.092416 · Cited by 331
Molecular paleontology of transposable elements in the Drosophila melanogaster genome
Kapitonov, V. V., & Jurka, J. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0732024100 · Cited by 288
Metadata
- Authors
- Eickbush, T. H., & Malik, H. S.
- Venue
- Mobile DNA II
- Publisher
- Wiley
- Published
- 2007-07-12
- Pages
- 1111-1144
- OpenAlex
- W1486570893
- Cited by
- 240
- References
- 6
- Type
- other
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Origins and Evolution of Retrotransposons. https://app.cochat.ai/papers/10.1128/9781555817954.ch49
- The paper
- Eickbush, T. H., & Malik, H. S. (2007). Origins and Evolution of Retrotransposons. Mobile DNA II. https://doi.org/10.1128/9781555817954.ch49
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
