A Novel Investigational Fc-Modified Humanized Monoclonal Antibody, Motavizumab-YTE, Has an Extended Half-Life in Healthy Adults
Robbie, Gabriel J., Criste, Ryan, Dall'Acqua, William F., Jensen, Kathryn, Patel, Nita K., Losonsky, Genevieve A., Griffin, M. Pamela·2013·Antimicrobial Agents and Chemotherapy
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- Preclinical and Clinical Investigations of Potential Drugs and Vaccines for COVID-19 Therapy: A Comprehensive Review With Recent UpdateMd. Easin Mia, Mithu Howlader, Farzana Akter, Md. Murad Hossain · 2024 · Clinical Pathology
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- Rat as a Predictive Model for Human Clearance and Bioavailability of Monoclonal AntibodiesJason Robarge, Kevin M. Budge, Lucy Her, Andrea M. Patterson, Patricia Brown‐Augsburger · 2024 · Antibodies
- Prevention of Respiratory Syncytial Virus Infection: From Vaccine to AntibodyKelly Huang, Herren Wu · 2014 · Microbiology Spectrum
- Neutralization Activity of Anti-drug Antibodies Against a Biotherapeutic Can Be Predicted from a Comprehensive Pharmacokinetics, Pharmacodynamics, and Anti-drug Antibody Data AnalysisWeifeng Xu, Brian M. Maas, Brad A. Roadcap, Aparna Swarup, Thomas Steinmetz, Linlin Luo, Marina Ichetovkin, Sandra Wood, Faye Vazvaei-Smith, Andrew Wen-Tseng Lee et al. · 2022 · The AAPS Journal
- The Development of Therapeutic Monoclonal Antibodies: Overview of the Nonclinical Safety AssessmentJanice A. Lansita, Barbara Mounho-Zamora · 2015 · Current Pain and Headache Reports
- Two-Pore Minimum Physiologically-based Pharmacokinetic Model to Describe the Disposition of Therapeutic Monoclonal IgG Antibody in HumansDeni Hardiansyah, Chee M. Ng · 2018 · Pharmaceutical Research
- Design and characterization of protective pan-ebolavirus and pan-filovirus bispecific antibodiesAriel S. Wirchnianski, Elisabeth K. Nyakatura, Andrew S. Herbert, Ana I. Kuehne, Shawn A. Abbasi, Catalina Florez, Nadia Storm, Lindsay G. A. McKay, Leandrew Dailey, Erin A. Kuang et al. · 2024 · PLoS Pathogens
- Mechanistic models of humoral kinetics following COVID-19 vaccinationDaniel Stocks, Amy C Thomas, Adam H.R. Finn, León Danon, Ellen Brooks‐Pollock · 2025 · Journal of The Royal Society Interface
- Antibody interfaces revealed through structural miningYizhou Yin, Matthew G. Romei, Kannan Sankar, Lipika R. Pal, Kam Hon Hoi, Yanli Yang, Brandon C. Leonard, Gladys de Leon Boenig, Nikit Kumar, Marissa Matsumoto et al. · 2022 · Computational and Structural Biotechnology Journal
- Tixagevimab/cilgavimab for prevention and treatment of COVID-19: a reviewAndrew Ustianowski · 2022 · Expert Review of Anti-infective Therapy
- Antibody Prophylaxis Against Dengue Virus 2 Infection in Non-Human PrimatesMonika Simmons, Robert J. Putnak, Peifang Sun, Timothy H. Burgess, Wayne Anthony Marasco · 2016 · American Journal of Tropical Medicine and Hygiene
- Vaccinal antibodies: Fc antibody engineering to improve the antiviral antibody response and induce vaccine-like effectsDhuha H Nawab · 2021 · Human Vaccines & Immunotherapeutics
- A generic platform to couple affinity chromatography with native mass spectrometry for the analysis of therapeutic monoclonal antibodiesVictoria C. Cotham, Anita P. Liu, Shunhai Wang, Ning Li · 2023 · Journal of Pharmaceutical and Biomedical Analysis
- Safety, Efficacy and Pharmacokinetics of AZD7442 (Tixagevimab/Cilgavimab) for Treatment of Mild-to-Moderate COVID-19: 15-Month Final Analysis of the TACKLE TrialRichard F. Hobbs, Hugh Montgomery, Francisco Padilla, Jesus Abraham Simón Campos, Douglas F. Arbetter, Seth Seegobin, Alexandre Kiazand, Katie L. Streicher, Nuria Martinez-Alier, Taylor S. Cohen et al. · 2024 · Infectious Diseases and Therapy
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- [3D-CT investigation of craniofacial and cervical spine anomalies in congenital muscular torticollis].Tülay Özer, Lokman Uzun, Varîm Numanoğlu, Ahmet Savranlar, Mübin Hoşnuter, Sadi Gündoğdu · 2004 · PubMed
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- Current Strategies for Pharmacokinetic OptimizationUli Binder, Arne Skerra · 2015 · AAPS advances in the pharmaceutical sciences series
- Membrane Proteins as Targets for Biological DrugsVanita D. Sood, Alec W. Gross · 2019 · Springer eBooks
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- An antibody cocktail targeting conserved, nonoverlapping epitopes prevents viral escape and confers protection against RSV in vivoYongpeng Sun, Liqin Liu, Zemin Jiang, Yizhen Wang, Jinghua Zhao, Hongsheng Qiang, Yujin Shi, Qi Lai, Li Chen, Qiangzhong Zhang et al. · 2026 · Science Translational Medicine
- Pharmacokinetics and Pharmacodynamics of Neonatal Fc Receptor (FcRn)-Targeting Therapeutic Proteins: a Systemic ReviewGirija Sharma, Yang Chen, Yan Chun Xu · 2023 · Current Pharmacology Reports
- Effect of FcRn Binding on Monoclonal Antibody Disposition in the BrainHsien Wei Huang, Shengjia Wu, Shufang Liu, Dhaval K. Shah · 2025 · The AAPS Journal
- Respiratory Syncytial Virus Protein Structure, Function and Implications for Subunit Vaccine DevelopmentMichael McCarthy, Tonya L. Villafana, Elizabeth A. Stillman, Mark Thomas Esser · 2014 · Future Virology
- SKY59, A Novel Recycling Antibody for Complement-mediated DiseasesTaku Fukuzawa, Jun‐ichi Nezu · 2019 · Current Medicinal Chemistry
- Implementation strategies for passive respiratory syncytial virus immunisationCharles Sande · 2021 · The Lancet Infectious Diseases
- Nirsevimab: hacia la inmunización universal de la población infantil frente al virus respiratorio sincitialJordi Reina, Carla Iglesias · 2022 · Vacunas
- Reinventing Therapeutic Proteins: Mining a Treasure of New TherapiesSarfaraz K. Niazi, Zamara Mariam · 2023 · Biologics
- High Incidence of Respiratory Syncytial Virus in Children with Community-Acquired Pneumonia from a City in the Brazilian Pre-Amazon RegionValéria Costa Fontes, Hivylla Lorrana dos Santos Ferreira, Marilene Ribeiro, Aruanã Joaquim Matheus Costa Rodrigues Pinheiro, Carlos Eduardo Campos Maramaldo, Eduardo Willian de Alencar Pereira, Luís Batista, Antonio Júnior, Luís Felipe Lima Lobato, Fabiano Silva et al. · 2023 · Viruses
- Neonatal Genetic Delivery of Anti-Respiratory Syncytial Virus (RSV) Antibody by Non-Human Primate-Based Adenoviral Vector to Provide Protection against RSVRika Gomi, Anurag Sharma, Wenzhu Wu, Stefan Worgall · 2018 · Vaccines
- Monoclonal Antibody Therapy Protects Pharmacologically Immunosuppressed Mice from Lethal Infection with Influenza B VirusBindumadhav M. Marathe, Guha Asthagiri Arunkumar, Peter Vogel, Philippe Noriel Q. Pascua, Jeremy C. Jones, Richard J. Webby, Florian Krammer, Elena A. Govorkova · 2020 · Antimicrobial Agents and Chemotherapy
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- Evaluation of strategies to modify Anti-SARS-CoV-2 monoclonal antibodies for optimal functionality as therapeuticsRobert V. House, Thomas A. Broge, Todd J. Suscovich, Doris M. Snow, Milan T. Tomic, Genevieve H. Nonet, Kamaljit Bajwa, Guangyu Zhu, Zachary Martinez, Kyal Hackett et al. · 2022 · PLoS ONE
- Predicting pharmacokinetic profile of therapeutic antibodies after iv injection from only the data after sc injection in cynomolgus monkeyKenta Haraya, Tatsuhiko Tachibana, Jun‐ichi Nezu · 2016 · Xenobiotica
- Half-life extension and immunogenicity in therapeutic proteins: mechanisms, trade-offs, and a decision frameworkYingping Chen, Yinchu Song, Yiwen Xie, Jianyi Pan · 2026 · Biochemical Pharmacology
- Systematic Review: Efficacy, Safety Profile, and Cost-Effectiveness of Nirsevimab Versus Palivizumab for RSV Prevention in Children Under 24 MonthsAndreea Văduva, Alexandru Dinulescu, Anca Cristina Drăgănescu, Sorin Claudiu Man, DA Plesca · 2026 · Children
- Development of therapeutic antibodies for the treatment of infection diseases and future aspectKenta Haraya, Keisuke Gotanda, Rie Shiokawa, Maiko Hoshino, Chiyomi Kubo, Taichi Kuramochi · 2022 · Drug Delivery System
- Severe COVID-19: Drugs and Clinical TrialsHazael Ramiro Ceja-Gálvez, Francisco Israel Renteria-Flores, Ferdinando Nicoletti, Jorge Hernández‐Bello, Gabriela Macedo Ojeda, José Francisco Muñóz-Valle · 2023 · Journal of Clinical Medicine
- Monoclonal Antibodies: From Structure to Therapeutic ApplicationRong Deng, Junyi Li, C. Andrew Boswell, Amita Joshi, Chunze Li · 2024 · Springer eBooks
- Safety, pharmacokinetics and pharmacodynamics of SHR-1703, an innovative long-acting anti-interleukin-5 monoclonal antibody, in healthy subjects: a randomized, double-blind, dose-escalation, placebo-controlled phase I studyLing Yang, Yuan Fang, Yuan Luo, Meng Fu, Kai Shen, Zhu Luo · 2024 · Expert Opinion on Investigational Drugs
- Algorithmic multiscale analysis for the FcRn mediated regulation of antibody PK in humanDimitrios G. Patsatzis, Shengjia Wu, Dhaval K. Shah, Dimitris A. Goussis · 2022 · Scientific Reports
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- Model-informed target product profiles of long acting-injectables for use as seasonal malaria preventionLydia Burgert, Theresa Reiker, Monica Golumbeanu, Jörg J. Möhrle, Melissa A. Penny · 2021 · medRxiv
- Enhancement of Protein–Protein Interactions by Destabilizing Mutations Revealed by HDX-MSYoshitomo Hamuro, Anthony Armstrong, Jeffrey D. Branson, Sheng‐Jiun Wu, Richard Y.‐C. Huang, Steven Jacobs · 2025 · Biomolecules
- Recent developments in pediatric respiratory syncytial virus prevention: The expanding role of monoclonal antibodiesChristine E. Tabulov, Kristy M. Shaeer · 2026 · American Journal of Health-System Pharmacy
- Generation and characterization of QLS22001, a humanized monoclonal antibody that neutralizes IL-17A and IL-17F with an extended half-lifeHuimin Ma, Wei Zhang, Ke Liu, Baoxin Xu, Min-Yu Li, Qingyun Meng, Zhenming An, Bo Chen · 2023 · International Immunopharmacology
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- Bispecific antibodies: A promising entrant in cancer immunotherapySamvedna Saini, Yatender Kumar · 2021 · Elsevier eBooks
- Mechanistically Weighted Metric to Predict In Vivo Antibody-Receptor Occupancy: An Analytical ApproachEshita Khera, Jaeyeon Kim, Andrew Marc Stein, Matt Ratanapanichkich, Greg M. Thurber · 2023 · Journal of Pharmacology and Experimental Therapeutics
- Long‐Circulating Nanobody Confers Durable Prophylaxis against Severe Acute Respiratory Syndrome Coronavirus 2 Omicron InfectionGeetha Satya Sainaga Jyothi Vaskuri, Gang Ye, Fan Bu, Dong Yang, Colleen Beth Jonsson, Hailey Turner‐Hubbard, Sydney R. Winecke, Alise Mendoza, Fang Li, Chalet Tan · 2025 · Advanced NanoBiomed Research
- Monoclonal antibodies in veterinary antiviral immunotherapy: technologies, applications and challengesSerkan Kökkaya, Ayşe Gençay Göksu, İbrahim Sözdutmaz, Muhammed Arif Toy, Engin Berber · 2025 · Veterinary Research Communications
- Multivalent nanobodies for potent and broad neutralization of Staphylococcus aureus toxinsY S Kim, Nicholas R. Walton, Wei Huang, Madison Lee, Yufei Xiang, Zhe Sang, Chaya Sussman, Sarah K. Moore, Derek J. Taylor, K Chen et al. · 2026 · Nature Communications
- Virus Reduction Neutralization Test and LI-COR Microneutralization Assay Bridging and WHO International Standard Calibration Studies for Respiratory Syncytial VirusDengyun Sun, Ying Homan, Joseph M. Antonello, Danila G. Giacone, Leah Bogardus, Yuhua Zhang, Wen Ming Feng, Ivette Caro-Aguilar, Amy Han-Ming Hsu, Shara M. Dellatore et al. · 2022 · Bioanalysis
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- Monoclonal Antibody Therapies Against SARS-CoV-2: Promises and RealitiesDaniele Focosi · 2024 · Current topics in microbiology and immunology
- “REAl LIfe” observational study on the effectiveness of Evusheld prophylaxis against SARS-CoV-2 omicron variants in vaccine non-responder immunocompromised patients (REALISE)Giuliana Lucia Esposito, Federico Fassio, Daniela Girardi, Erica Picasso, Federica Meloni, Simone Montini, Veronica Codullo, Eleonora Francesca Pattonieri, Irene Defrancesco, Antonio Bianchessi et al. · 2024 · Vaccine
- Engineered IgG Fc-conjugation prolongs the half-life of florfenicol and alleviates pneumonia in miceShikun Ge, Mei Dang, Alberto Carlos Pires Dias, Xiaoying Zhang · 2024 · Biochimie
- A humanised ACE2, TMPRSS2, and FCGRT mouse model reveals the protective efficacy of anti-receptor binding domain antibodies elicited by SARS-CoV-2 hybrid immunityFernanda Ana‐Sosa‐Batiz, Shailendra Kumar Verma, Norazizah Shafee, Robyn Miller, Chris Conner, Kathryn M. Hastie, Julia Timis, Erin Maule, Michael N. Nguyen, Linda Tran et al. · 2025 · EBioMedicine
- An antidote approach to reduce risk and broaden utility of antibody-based therapeuticsAlyse D. Portnoff, Cuihua Gao, M. Jack Borrok, Xizhe Gao, Changshou Gao, G. Jonah Rainey · 2017 · Journal of Biological Chemistry
- Physiology and Pathology of Multidrug-Resistant Bacteria: Antibodies- and Vaccines-Based Pathogen-Specific TargetingYang Zhang, Jie Su, Donghui Wu · 2017 · InTech eBooks
- RECOMBINANT ANTIBODIES IN ANTI-VIRAL THERAPY: ACHIEVEMENTS AND PERSPECTIVESAlexey S. Oksanich, Alexandra A. Nikonova, Vitaly V. Zverev · 2018 · Journal of microbiology epidemiology immunobiology
- Pharmacological and non-pharmacological strategies in coronavirus disease 2019: A literature reviewFrancisco J. González-Ruiz · 2022 · Annals of Medicine and Surgery
- Respiratory Syncytial Virus Vaccines and Monoclonal AntibodiesRuth A. Karron · 2023 · Elsevier eBooks
- [Progress in monoclonal antibody-based immunotherapy for cancer treatment].Yajun Guo · 2015 · PubMed
- Role of IgD in prevention and treatment of SARS CoV-2 infection “The Hidden Soldier"Donia H. Sheir · 2020 · Microbial Biosystems
- Improvement of Key Characteristics of AntibodiesNeil Brewis · 2020 · Learning materials in biosciences
- A highly expressing, soluble, and stable plant-made IgG fusion vaccine strategy enhances antigen immunogenicity in mice without adjuvantAndrew G. Diamos, Mary D. Pardhe, Haiyan Sun, Joseph G. L. Hunter, Jacquelyn A. Kilbourne, Qiang Chen, Hugh S. Mason · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
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- Antibody-Based Therapeutics for HypercholesterolemiaBrian Tomlinson, Paul Chan · 2025 · Biologics
- Pharmacokinetic considerations and strategies for antibody-based therapeuticsJuanhong Zhang, Rong Chang, Anpeng Zhao, Xuefeng Li, Yuemei Sun, Junmin Zhang, Rong Wang, Tengchuan Jin · 2025 · Drug Metabolism Reviews
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- Quantitative Prediction of Human Pharmacokinetics for Fc‐Engineered Therapeutic Monoclonal Antibodies With Increased FcRn Binding Mutations After Subcutaneous InjectionKenta Haraya, Taichi Kuramochi · 2026 · Clinical and Translational Science
- Open-label phase 1b/2 trial of navenibart, a long-acting plasma kallikrein inhibitor for hereditary angioedemaAleena Banerji, Timothy Craig, Karl V. Sitz, H. Henry Li, William Lumry, Adil Adatia, William Yang, Josh S. Jacobs, Raffi Tachdjian, Weily Soong et al. · 2026 · Journal of Allergy and Clinical Immunology
- YTE-engineered antibodies: From neonatal Fc receptor binding mechanisms to next-generation therapeuticsSuneetkumar Diwakar Dubey · 2026 · International Journal of Molecular and Immuno Oncology
- Broadly neutralizing nanobodies target a defined structural pivot site on the RSV fusion proteinQianqian Wang, Xianliang Ke, Entao Li, Dongxiang Hong, Zekai Cheng, Hongxin Li, Jiachen Zhang, Tengchuan Jin, Rui Gong, Bo Shu et al. · 2026 · EMBO Molecular Medicine
- High-dose biologics and bioconjugates delivery: Integrating molecular optimization with device design and routes of administrationNaresh K. Budhavaram, Kevin Harrison Duffy, Abraham H. Abouzeid, Reshma Bharadwaj, Nisha Shrestha, Elisa Schrader Echeverri, Chris Mitchener, J. Anand Subramony · 2026 · Advanced Drug Delivery Reviews
- The preclinical discovery and development of depemokimab for severe eosinophilic asthmaMario Cazzola, Vincenzo Patella, Raffaella Pagliaro, Andrea Bianco, Paola Rogliani, Maria Gabriella Matera · 2026 · Pulmonary Pharmacology & Therapeutics
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