The DOI matches its Crossref record; 71 of the 71 references it cites were found in a registry or an index.
The Resistome of Pseudomonas aeruginosa in Relationship to Phenotypic Susceptibility
Open accessAbstract
Many clinical isolates of Pseudomonas aeruginosa cause infections that are difficult to eradicate due to their resistance to a wide variety of antibiotics. Key genetic determinants of resistance were identified through genome sequences of 390 clinical isolates of P. aeruginosa , obtained from diverse geographic locations collected between 2003 and 2012 and were related to microbiological susceptibility data for meropenem, levofloxacin, and amikacin. β-Lactamases and integron cassette arrangements were enriched in the established multidrug-resistant lineages of sequence types ST111 (predominantly O12) and ST235 (O11). This study demonstrates the utility of next-generation sequencing (NGS) in defining relevant resistance elements and highlights the diversity of resistance determinants within P. aeruginosa . This information is valuable in furthering the design of diagnostics and therapeutics for the treatment of P. aeruginosa infections.
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Cited by
Horcajada, J. P., Montero, M., Oliver, A., Sorlí, L., Luque, S., Gómez-Zorrilla, S., Benito, N., & Grau, S. (2019) · Clinical Microbiology Reviews · doi:10.1128/cmr.00031-19 · Cited by 961
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Mechanisms of antimicrobial resistance in Gram-negative bacilli
Ruppé, É., Woerther, P.-L., & Barbier, F. (2015) · Annals of Intensive Care · doi:10.1186/s13613-015-0061-0 · Cited by 490
Genome-Based Prediction of Bacterial Antibiotic Resistance
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Innovative and rapid antimicrobial susceptibility testing systems
van Belkum, A., Burnham, C.-A. D., Rossen, J. W. A., Mallard, F., Rochas, O., & Dunne, W. M. (2020) · Nature Reviews Microbiology · doi:10.1038/s41579-020-0327-x · Cited by 355
Metadata
- Authors
- Kos, V. N., Déraspe, M., McLaughlin, R. E., Whiteaker, J. D., Roy, P. H., Alm, R. A., Corbeil, J., & Gardner, H.
- Venue
- Antimicrobial Agents and Chemotherapy
- Publisher
- American Society for Microbiology
- Published
- 2015-01
- Volume
- 59
- Issue
- 1
- Pages
- 427-436
- ISSN
- 0066-4804 (ISSN-L)
- 1098-6596
- OpenAlex
- W2133740160
- Cited by
- 264
- References
- 71
- FWCI
- 8.73
- Type
- journal article
- Language
- en
- Open access
- green
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- Kos, V. N., Déraspe, M., McLaughlin, R. E., Whiteaker, J. D., Roy, P. H., Alm, R. A., Corbeil, J., & Gardner, H. (2015). The Resistome of Pseudomonas aeruginosa in Relationship to Phenotypic Susceptibility. Antimicrobial Agents and Chemotherapy. https://doi.org/10.1128/aac.03954-14
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
