The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Inhibition of Influenza Virus Ribonucleic Acid Polymerase by Ribavirin Triphosphate
Open accessAbstract
Ribavirin 5′-triphosphate (RTP), derived from the broad-spectrum antiviral compound ribavirin (Virazole), can selectively inhibit influenza virus ribonucleic acid polymerase in a cell-free assay. Ribavirin and its 5′-monophosphate have no effect on the polymerase. The inhibition is competitive with respect to adenosine 5′-triphosphate and guanosine 5′-triphosphate. RTP also inhibits ApG- and GpC-stimulated influenza virus ribonucleic acid polymerase. Since ribavirin is phosphorylated in the cell, the inhibition of influenza multiplication in the cell may also be caused by RTP.
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Citations
Cites
Ribonucleic Acid Synthesis of Vesicular Stomatitis Virus, II. An RNA Polymerase in the Virion
Baltimore, D., Huang, A. S., & Stampfer, M. (1970) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.66.2.572 · Cited by 368
Cited by
SAIJO, M., MORIKAWA, S., FUKUSHI, S., MIZUTANI, T., HASEGAWA, H., NAGATA, N., IWATA, N., & KURANE, I. (2005) · Antiviral Research · doi:10.1016/j.antiviral.2005.01.003 · Cited by 82
Metadata
- Authors
- Eriksson, B., Helgstrand, E., Johansson, N. G., Larsson, A., Misiorny, A., Noren, J. O., Philipson, L., Stenberg, K., Stening, G., Stridh, S., & Öberg, B.
- Venue
- Antimicrobial Agents and Chemotherapy
- Publisher
- American Society for Microbiology
- Published
- 1977-06
- Volume
- 11
- Issue
- 6
- Pages
- 946-951
- ISSN
- 0066-4804 (ISSN-L)
- 1098-6596
- OpenAlex
- W2026106960
- Cited by
- 257
- References
- 1
- FWCI
- 9.26
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: Inhibition of Influenza Virus Ribonucleic Acid Polymerase by Ribavirin Triphosphate. https://app.cochat.ai/papers/10.1128/aac.11.6.946
- The paper
- Eriksson, B., Helgstrand, E., Johansson, N. G., Larsson, A., Misiorny, A., Noren, J. O., Philipson, L., Stenberg, K., Stening, G., Stridh, S., & Öberg, B. (1977). Inhibition of Influenza Virus Ribonucleic Acid Polymerase by Ribavirin Triphosphate. Antimicrobial Agents and Chemotherapy. https://doi.org/10.1128/aac.11.6.946
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
