The DOI matches its Crossref record; 17 of the 17 references it cites were found in a registry or an index.
In vitro susceptibility of Trichomonas vaginalis to 50 antimicrobial agents
Open accessAbstract
We determined the susceptibilities of five strains of Trichomonas vaginalis, one of which was metronidazole resistant, to 50 antimicrobial agents. For the metronidazole-susceptible strains, the most active agents were metronidazole, tinidazole, mebendazole, furazolidone, and anisomycin. Against the resistant strain mebendazole, furazolidone, and anisomycin were the most active. Antifungal agents, beta-lactams, macrolides, aminoglycosides, and folic acid antagonists were ineffective against all strains.
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“Mebendazole was also shown to be effective against metronidazole-resistant and metronidazole-sensitive T. vaginalis strains in vitro [30,285].”
From Albendazole and Mebendazole as Anti-Parasitic and Anti-Cancer Agents: an Update (2021) · cites this paper as [30]
Citations
Cites
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Cited by
Sorted by citations
Freeman, C. D., Klutman, N. E., & Lamp, K. C. (1997) · Drugs · doi:10.2165/00003495-199754050-00003 · Cited by 489
Treatment of Infections Caused by Metronidazole-ResistantTrichomonas vaginalis
Cudmore, S. L., Delgaty, K. L., Hayward-McClelland, S. F., Petrin, D., & Garber, G. E. (2004) · Clinical Microbiology Reviews · doi:10.1128/cmr.17.4.783-793.2004 · Cited by 310
Albendazole and Mebendazole as Anti-Parasitic and Anti-Cancer Agents: an Update
Chai, J.-Y., Jung, B.-K., & Hong, S.-J. (2021) · The Korean Journal of Parasitology · doi:10.3347/kjp.2021.59.3.189 · Cited by 286
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Synthesis and antiparasitic activity of 1H-benzimidazole derivatives
Valdez, J., Cedillo, R., Hernández‐Campos, A., Yépez‐Mulia, L., Hernández‐Luis, F., Navarrete‐Vázquez, G., Tapia‐Contreras, A., Cortés-Zárate, R., Hernández, M., & Castillo, R. (2002) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/s0960-894x(02)00346-3 · Cited by 269
Metadata
- Authors
- Sears, S. D., & O'Hare, J.
- Affiliations
- Department of Medicine, Wyman Park Health System, Baltimore, Maryland 21211.
- Venue
- Antimicrobial Agents and Chemotherapy
- Publisher
- American Society for Microbiology
- Published
- 1988-01
- Volume
- 32
- Issue
- 1
- Pages
- 144-146
- ISSN
- 0066-4804 (ISSN-L)
- 1098-6596
- PMC
- PMC172117
- OpenAlex
- W2036259942
- Cited by
- 61
- References
- 17
- Citations by year
- 2025: 3 · 2022: 1 · 2021: 3 · 2020: 3 · 2019: 4 · 2018: 2 · 2017: 5 · 2013: 1 · 2012: 1
- FWCI
- 2.47
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Antimicrobial Agents and Chemotherapy (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Immunology and Microbiology › Microbiology › Reproductive tract infections research
- Health Sciences › Medicine › Microbiology (medical) › Bacterial Identification and Susceptibility Testing
- Health Sciences › Medicine › Urology › Urinary Tract Infections Management
- Keywords
- Trichomonas vaginalis, trichomoniasis, antimicrobial susceptibility, metronidazole resistance, tinidazole, mebendazole, furazolidone, anisomycin, antifungal agents, beta-lactam antibiotics, macrolides, aminoglycosides, antifolate
- MeSH terms
- Animals, Anthelmintics, Anti-Infective Agents, Anti-Bacterial Agents, Antifungal Agents, Antiprotozoal Agents, Drug Resistance, Folic Acid Antagonists, Humans, Metronidazole, Trichomonas vaginalis
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