The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.
Activities of the four optical isomers of 2',3'-dideoxy-3'-thiacytidine (BCH-189) against human immunodeficiency virus type 1 in human lymphocytes
Open accessAbstract
Four different isomers of 2',3'-dideoxy-3'-thiacytidine [beta-DL-(+-)-BCH-189] were evaluated in primary human lymphocytes infected with human immunodeficiency virus type 1. The beta-L-(-) isomer was the most potent enantiomer, with a median effective concentration of 1.8 nM and no discernible cytotoxicity up to 100 microM. The relative order of potencies for the isomers was beta-L-(-) greater than beta-DL-(+-) racemic greater than beta-D-(+) greater than alpha-L-(+) greater than alpha-D-(-). The beta-L-(-) enantiomer was as potent as 3'-azido-3'-deoxythymidine.
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Common evolutionary origin of hepatitis B virus and retroviruses.
Miller, R. H., & Robinson, W. S. (1986) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.83.8.2531 · Cited by 204
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Self-citationLin, T. S., Schinazi, R. F., Griffith, B. P., August, E. M., Eriksson, B., Zheng, D., Huang, L. A., & Prusoff, W. H. (1989) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.33.12.2149 · Cited by 109
Self-citation(±)-Dioxolane-T ((±)-1-[(2β,4β)-2-(hydroxymethyl)-4-dioxolanyl]thymine)
Norbeck, D. W., Spanton, S. G., Broder, S. E., & Mitsuya, H. (1989) · Tetrahedron Letters · doi:10.1016/s0040-4039(01)93868-7 · Cited by 96
Preparation of the geometric isomers of DDC, DDA, D4C and D4T as potential anti-HIV agents
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Mimtsoudis, I., Tsachouridou, O., Akinosoglou, K., & Metallidis, S. (2024) · Viruses · doi:10.3390/v16091392 · Cited by 13
Metadata
- Authors
- Schinazi, R. F., Chu, C. K., Peck, A., McMillan, A., Mathis, R., Cannon, D., Jeong, L. S., Beach, J. W., Choi, W. B., & Yeola, S.
- Venue
- Antimicrobial Agents and Chemotherapy
- Publisher
- American Society for Microbiology
- Published
- 1992-03
- Volume
- 36
- Issue
- 3
- Pages
- 672-676
- ISSN
- 0066-4804 (ISSN-L)
- 1098-6596
- OpenAlex
- W2166336747
- Cited by
- 265
- References
- 13
- FWCI
- 18.23
- Type
- journal article
- Language
- en
- Open access
- green
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- Schinazi, R. F., Chu, C. K., Peck, A., McMillan, A., Mathis, R., Cannon, D., Jeong, L. S., Beach, J. W., Choi, W. B., & Yeola, S. (1992). Activities of the four optical isomers of 2',3'-dideoxy-3'-thiacytidine (BCH-189) against human immunodeficiency virus type 1 in human lymphocytes. Antimicrobial Agents and Chemotherapy. https://doi.org/10.1128/aac.36.3.672
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
