Detection of amphotericin B-resistant Candida isolates in a broth-based system
Open accessAbstract
Because of the limited ability of the National Committee for Clinical Laboratory Standards proposed M27P methodology to detect resistance to amphotericin B by Candida isolates, we sought to identify alternative media and pH conditions that could reliably identify resistant isolates. Antibiotic Medium 3 broth (also known as Penassay broth) buffered to pH 5 or pH 7 produced superior results and readily identified a series of resistant isolates.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The susceptibility of Candida to currently available antifungal agents can be predicted if the species of the infecting isolate is known.
“Although the susceptibility of Candida to the currently available antifungal agents can be predicted if the species of the infecting isolate is known (table 3) [1,4,6,[11][12][13][14][15][16][17][20][21][22][23][24], individual isolates do not necessarily follow the general pattern.”
From Guidelines for Treatment of Candidiasis (2004) · cites this paper as [6]
Variations of the M27-A2 methodology using different media, agar-based MIC methods, and measurements of minimum fungicidal concentrations appear to enhance detection of resistant isolates.
“Variations of the M27-A2 methodology using different media [6], agar-based MIC methods [12,35,36], and measurements of minimum fungicidal concentrations [11] appear to enhance detection of resistant isolates.”
From Guidelines for Treatment of Candidiasis (2004) · cites this paper as [6]
The NCCLS M27-A2 methodology does not reliably identify amphotericin B-resistant isolates.
“The NCCLS M27-A2 methodology does not reliably identify amphotericin B-resistant isolates [6].”
From Guidelines for Treatment of Candidiasis (2004) · cites this paper as [6]
Recent surveys from France, Italy, Switzerland, Finland, Iceland, Taiwan, and Norway indicate that C. glabrata has not increased as a cause of invasive candidiasis to the extent seen in the United States, despite increased fluconazole use in each of those countries.
“and recent surveys from France (254), Italy (139, 289), Switzerland (147), Finland (234), Iceland (11), Taiwan (33, 34, 107, 108), and Norway (259) indicate that C. glabrata has not increased as a cause of IC to the extent in the United States despite an increase in the use of fluconazole in each of those countries.”
From Epidemiology of Invasive Candidiasis: a Persistent Public Health Problem (2007) · cites this paper as [254]
The citation lists haven’t been fetched yet
References 10 · Cited by 198
- Authors
- Rex, J. H., Cooper, C. R., Merz, W. G., Galgiani, J. N., & Anaissie, E. J.
- Affiliations
- Department of Internal Medicine, University of Texas Medical School, Houston, USA.
- Venue
- Antimicrobial Agents and Chemotherapy
- Publisher
- American Society for Microbiology
- Published
- 1995-04
- Volume
- 39
- Issue
- 4
- Pages
- 906-909
- ISSN
- 0066-4804 (ISSN-L)
- 1098-6596
- PMC
- PMC162651
- OpenAlex
- W2127678665
- Cited by
- 198
- References
- 10
- Citations by year
- 2024: 2 · 2023: 1 · 2022: 1 · 2021: 5 · 2020: 1 · 2019: 2 · 2017: 4 · 2016: 1 · 2015: 3 · 2014: 3 · 2013: 3 · 2012: 4
- FWCI
- 12.13
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Locations
- Antimicrobial Agents and Chemotherapy (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
- Life Sciences › Agricultural and Biological Sciences › Ecology, Evolution, Behavior and Systematics › Fungal Plant Pathogen Control
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Fungal and yeast genetics research
- Keywords
- amphotericin B resistance, Candida
- MeSH terms
- Amphotericin B, Candida, Culture Media, Drug Resistance, Microbial
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
