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A Canadian National Surveillance Study of Urinary Tract Isolates from Outpatients: Comparison of the Activities of Trimethoprim-Sulfamethoxazole, Ampicillin, Mecillinam, Nitrofurantoin, and Ciprofloxacin

Open access
Zhanel, George G., Karlowsky, James A., Harding, Godfrey K. M., Carrie, Anita, Mazzulli, Tony, Low, Donald E., The Canadian Urinary Isolate Study Group, Hoban, Daryl J.·2000·Antimicrobial Agents and Chemotherapy

Abstract

Ampicillin, trimethoprim-sulfamethoxazole, mecillinam, nitrofurantoin, and ciprofloxacin mean resistance rates for 2,000 urinary tract isolates collected from outpatients across Canada in 1998 were 41.1, 19.2, 14.7, 5.0, and 1.8%, respectively. For Escherichia coli isolates alone ( n = 1,681) comparable rates were 41.0, 18.9, 7.4, 0.1, and 1.2%, respectively. The majority of E. coli isolates resistant to ampicillin, trimethoprim-sulfamethoxazole, or ciprofloxacin were susceptible (MIC, <16 μg/ml) to mecillinam.

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Metadata

Authors
Zhanel, G. G., Karlowsky, J. A., Harding, G. K. M., Carrie, A., Mazzulli, T., Low, D. E., The Canadian Urinary Isolate Study Group, & Hoban, D. J.
Venue
Antimicrobial Agents and Chemotherapy
Published
2000-04
Volume
44
Issue
4
Pages
1089-1092
ISSN
  • 0066-4804 (ISSN-L)
  • 1098-6596
OpenAlex
W2119643139
Cited by
190
References
0
FWCI
9.27
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: A Canadian National Surveillance Study of Urinary Tract Isolates from Outpatients: Comparison of the Activities of Trimethoprim-Sulfamethoxazole, Ampicillin, Mecillinam, Nitrofurantoin, and Ciprofloxacin. https://app.cochat.ai/papers/10.1128/aac.44.4.1089-1092.2000
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Zhanel, G. G., Karlowsky, J. A., Harding, G. K. M., Carrie, A., Mazzulli, T., Low, D. E., The Canadian Urinary Isolate Study Group, & Hoban, D. J. (2000). A Canadian National Surveillance Study of Urinary Tract Isolates from Outpatients: Comparison of the Activities of Trimethoprim-Sulfamethoxazole, Ampicillin, Mecillinam, Nitrofurantoin, and Ciprofloxacin. Antimicrobial Agents and Chemotherapy. https://doi.org/10.1128/aac.44.4.1089-1092.2000

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.