Epidemiology of Human Metapneumovirus
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SUMMARY: Since the discovery of human metapneumovirus (hMPV) in 2001, the virus has been identified worldwide. hMPV is a common respiratory pathogen, particularly in infants and young children. The virus is associated with both upper and lower respiratory tract infections and may be a trigger for asthma. At least two major genotypes of hMPV circulate during community outbreaks. Whether these genotypes represent distinct serotypes remains controversial. The major challenges faced by the medical and scientific communities are the understanding of the pathogenesis of hMPV disease and the development of a safe and effective vaccine to protect against infection and disease caused by this newly recognized respiratory virus.
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TLR3 responds to the presence of many respiratory viruses, including rhinoviruses, RSV, and influenza viruses.
“TLR3 responds to the presence of many respiratory viruses, including rhinoviruses (107, 137), RSV (89), and influenza viruses (90).”
From The airway epithelium: soldier in the fight against respiratory viruses (2011) · cites this paper as [137]
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References 145 · Cited by 355
Research works printed but not linked: 1
- [114]Stockton, J., I. Stephenson, D. Fleming, and M. Zambon. 2002. Human metapneumovirus as a cause of community-acquired respiratory illness. Emerg. Infect. Dis. 8:897-901. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Authors
- Kahn, J. S.
- Affiliations
- Yale University (US)
- Corresponding author
- Kahn, Jeffrey S.
- ORCID
- Kahn, Jeffrey S.
- Venue
- Clinical Microbiology Reviews
- Publisher
- American Society for Microbiology
- Published
- 2006-07
- Volume
- 19
- Issue
- 3
- Pages
- 546-557
- ISSN
- 0893-8512 (ISSN-L)
- 1098-6618
- PMC
- PMC1539100
- OpenAlex
- W2171602693
- Cited by
- 355
- References
- 145
- Citations by year
- 2026: 26 · 2025: 39 · 2024: 12 · 2023: 8 · 2022: 12 · 2021: 7 · 2020: 18 · 2019: 8 · 2018: 19 · 2017: 16 · 2016: 13 · 2015: 23 · 2014: 18 · 2013: 25 · 2012: 16
- FWCI
- 2.56
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Clinical Microbiology Reviews (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Epidemiology › Respiratory viral infections research
- Health Sciences › Medicine › Epidemiology › Virology and Viral Diseases
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Viral Infections and Immunology Research
- Keywords
- human metapneumovirus, epidemiology, respiratory infections, infants and young children, asthma, viral genotypes, serotypes, pathogenesis, vaccine development
- MeSH terms
- Child, Preschool, Humans, Respiratory Tract Infections, Seasons, Molecular Epidemiology, Paramyxoviridae Infections, Metapneumovirus
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