The DOI matches its Crossref record; 497 of the 497 references it cites were found in a registry or an index.
Infections Caused by Scedosporium spp
Open accessAbstract
SUMMARY: Scedosporium spp. are increasingly recognized as causes of resistant life-threatening infections in immunocompromised patients. Scedosporium spp. also cause a wide spectrum of conditions, including mycetoma, saprobic involvement and colonization of the airways, sinopulmonary infections, extrapulmonary localized infections, and disseminated infections. Invasive scedosporium infections are also associated with central nervous infection following near-drowning accidents. The most common sites of infection are the lungs, sinuses, bones, joints, eyes, and brain. Scedosporium apiospermum and Scedosporium prolificans are the two principal medically important species of this genus. Pseudallescheria boydii , the teleomorph of S. apiospermum , is recognized by the presence of cleistothecia. Recent advances in molecular taxonomy have advanced the understanding of the genus Scedosporium and have demonstrated a wider range of species than heretofore recognized. Studies of the pathogenesis of and immune response to Scedosporium spp. underscore the importance of innate host defenses in protection against these organisms. Microbiological diagnosis of Scedosporium spp. currently depends upon culture and morphological characterization. Molecular tools for clinical microbiological detection of Scedosporium spp. are currently investigational. Infections caused by S. apiospermum and P. boydii in patients and animals may respond to antifungal triazoles. By comparison, infections caused by S. prolificans seldom respond to medical therapy alone. Surgery and reversal of immunosuppression may be the only effective therapeutic options for infections caused by S. prolificans .
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Scedosporium prolificans, a recently emerging human fungal pathogen of the respiratory system, may also form biofilms, given that fungus balls, resembling biofilm structures, have been observed in some clinical cases (30).”
From Candida albicans Biofilms and Human Disease (2015) · cites this paper as [30]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Yarbrough, W. M., Robbins, R. C., & Mallidi, H. R. (2016) · CRC Press eBooks · doi:10.3109/9781439802571-25 · Cited by 2,161
Report of a case and review of the literature
Kamalian, N., Abbassioun, K., Amirjamshidi, A., et al. (1987) · Cited by 1,576
Epidemiology and Outcome of Mould Infections in Hematopoietic Stem Cell Transplant Recipients
Marr, K. A., Carter, R. A., Crippa, F., Wald, A., & Corey, L. (2002) · Clinical Infectious Diseases · doi:10.1086/339202 · Cited by 1,446
de Hoog, S., Guarro, J., Gené, J., & Figueras, M. J. (2000) · UvA-DARE (University of Amsterdam) · Cited by 1,427
Sehulster, L. M., & Chinn, R. Y. W. (2003) · PubMed · Cited by 1,418
Report of two cases and review of the literature
Ekovic, G. P. L., Mariwalla, N. R., Horn, E. M., Chang, S. W., Rekate, H. L., & Theodore, N. (2006) · Cited by 865
Medical Mycology. The Pathogenic Fungi and Pathogenic Actinomycetes.
(1976) · Annals of Internal Medicine · doi:10.7326/0003-4819-84-4-514_1 · Cited by 847
Medically Important Fungi: A Guide to Identification
Larone, D. H. (1976) · Cited by 809
Espinel‐Ingroff, A. (1998) · Journal of Clinical Microbiology · doi:10.1128/jcm.36.10.2950-2956.1998 · Cited by 576
The Beta-Glucan Receptor Dectin-1 Recognizes Specific Morphologies of Aspergillus fumigatus
Steele, C., Rapaka, R. R., Metz, A., Pop, S. M., Williams, D. L., Gordon, S., Kolls, J. K., & Brown, G. D. (2005) · PLoS Pathogens · doi:10.1371/journal.ppat.0010042 · Cited by 509
Research works printed but not linked: 15
- Ballingalli, G. R. 1855. An account of a tumor affecting the foot. Trans. Med. Phys. Soc. Bombay2:273-276.
- Brumpt, E. 1906. Les mycetomes. Arch. Parasitol.10:489-564.
- Carter, H. 1860. On a new striking form of fungus disease principally affecting the foot and prevailing endemically in many parts of India. Trans. Med. Phys. Soc. Bombay60:140-142.
- Carter, H. V. 1861. On mycetoma or the fungus disease of India including notes of recent cases and new observations of the structure, etc. of the entophytic growth. Trans. Med. Physiol. Soc. Bombay7:206-221.
- Dignani, M. C., N. Kiwan, and E. J. Anaissie. 2003. Hyalohyphomycoses, p. 309-324. In E. J. Anaissie, M. R. McGinnis, and M. A. Pfaller (ed.), Clinical mycology. Churchill Livingstone, Philadelphia, PA.
- Eyre, E. W. 1859. An account of a peculiar disease “tubercular” of the foot. Ind. Ann. Med. Sci.6:513-520.
- Godfrey, J. 1846. Diseases of the foot not hitherto described. Lanceti:593-594.
- Gueho, E., and G. S. de Hoog. 1991. Taxonomy of the medical species of Pseudallescheria and Scedosporium. J. Mycol. Méd.1:3-9.
- 10.1128/CMR.13.4.662 · DOI
- Malloch, D., and I. A. Salkin. 1984. A new species of Scedosporium associated with osteomyelitis in humans. Mycotaxon21:247-255.
- McGinnis, M. R., A. A. Padhye, and L. Ajello. 1982. Pseudallescheria Negroni et Fischer, 1943 and its later synonym Petriellidium Malloch, 1970. Mycotaxon14:94-102.
- Pinoy, E. 1913. Actinomycoses and mycetomas. Borntragen (Leipzig)11:929-938.
- Saccardo, P. A. 1911. Sylloge fungorum ommium hucusque cognitorum. Borntragen (Leipzig)4:282.
- Tarozzi, G. 1909. Ricerche anatomo-patologiehe, baceriologiehet e sperimentali sopra un caso di actinomicosi del piede. Arch. Perle Sc. Med.33:553-632.
- Werner, P. G. 2006. Myco-heterotrophs: hacking the mycorrhizal network. Mycena News57:8.
Cited by
Sorted by citations
Candida albicans Biofilms and Human Disease
Nobile, C. J., & Johnson, A. D. (2015) · Annual Review of Microbiology · doi:10.1146/annurev-micro-091014-104330 · Cited by 1,057
Histopathologic Diagnosis of Fungal Infections in the 21st Century
Guarner, J., & Brandt, M. E. (2011) · Clinical Microbiology Reviews · doi:10.1128/cmr.00053-10 · Cited by 1,007
Epidemiology of Invasive Mycoses in North America
Pfaller, M. A., & Diekema, D. J. (2010) · Critical Reviews in Microbiology · doi:10.3109/10408410903241444 · Cited by 901
Queiroz-Telles, F., de Hoog, S., Santos, D. W. C. L., Salgado, C. G., Vicente, V. A., Bonifaz, A., Roilides, E., Xi, L., Azevedo, C. D. M. P. E. S., da Silva, M. B., et al. (2017) · Clinical Microbiology Reviews · doi:10.1128/cmr.00032-16 · Cited by 360
Self-citationThe global burden of fungal diseases
Vallabhaneni, S., Mody, R. K., Walker, T., & Chiller, T. (2016) · Infectious Disease Clinics of North America · doi:10.1016/j.idc.2015.10.004 · Cited by 292
Metadata
- Authors
- Cortez, K. J., Roilides, E., Quiroz-Telles, F., Meletiadis, J., Antachopoulos, C., Knudsen, T., Buchanan, W., Milanovich, J., Sutton, D. A., Fothergill, A., Rinaldi, M. G., Shea, Y. R., Zaoutis, T., Kottilil, S., & Walsh, T. J.
- Affiliations
- Children's Hospital of Philadelphia (US)
- Immunocompromised Host Section, Pediatric Oncology Branch, National Cancer Institute, Bethesda, Maryland
- National Institutes of Health (US)
- Corresponding author
- Walsh, Thomas J.
- Venue
- Clinical Microbiology Reviews
- Publisher
- American Society for Microbiology
- Published
- 2008-01
- Volume
- 21
- Issue
- 1
- Pages
- 157-197
- ISSN
- 0893-8512 (ISSN-L)
- 1098-6618
- PMC
- PMC2223844
- OpenAlex
- W2158059832
- Cited by
- 786
- References
- 497
- Citations by year
- 2026: 31 · 2025: 47 · 2024: 52 · 2023: 59 · 2022: 29 · 2021: 42 · 2020: 48 · 2019: 36 · 2018: 35 · 2017: 68 · 2016: 45 · 2015: 46 · 2014: 41 · 2013: 50 · 2012: 31
- FWCI
- 4.83
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Clinical Microbiology Reviews (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
- Health Sciences › Medicine › Infectious Diseases › Fungal Infections and Studies
- Health Sciences › Medicine › Microbiology (medical) › Actinomycetales infections and treatment
- Keywords
- Scedosporium, Scedosporium apiospermum, Scedosporium prolificans, Pseudallescheria boydii, invasive fungal infections, immunocompromised patients, mycetoma, sinopulmonary infections, disseminated fungal infection, central nervous system infection, near-drowning, molecular taxonomy, pathogenesis, innate host defense, surgical debridement, molecular detection
- MeSH terms
- Administration, Inhalation, Animals, Antifungal Agents, Arthritis, Bone Diseases, Infectious, Humans, Immunosuppressive Agents, Mycetoma, Microbial Sensitivity Tests, Phylogeny, Respiratory Tract Infections, Eye Infections, Fungal, Immunocompromised Host, Central Nervous System Fungal Infections, Scedosporium, Biodiversity
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
