Cited by 962Antimicrobial Resistance in StaphylococcusAntibiotic Resistance in BacteriaAntibiotic Use and Resistance

The DOI matches its Crossref record; 405 of the 406 references it cites were found in a registry or an index.

Reduced Vancomycin Susceptibility in Staphylococcus aureus , Including Vancomycin-Intermediate and Heterogeneous Vancomycin-Intermediate Strains: Resistance Mechanisms, Laboratory Detection, and Clinical Implications

Open access

Howden, Benjamin P., Davies, John K., Johnson, Paul D. R., Stinear, Timothy P., Grayson, M. Lindsay·2010·Clinical Microbiology Reviews

DOI 10.1128/cmr.00042-09PMC PMC2806658

Open this paper in CoChat — free account

Abstract

SUMMARY: The emergence of vancomycin-intermediate Staphylococcus aureus (VISA) and heterogeneous vancomycin-intermediate Staphylococcus aureus (hVISA) over the past decade has provided a challenge to diagnostic microbiologists to detect these strains, clinicians treating patients with infections due to these strains, and researchers attempting to understand the resistance mechanisms. Recent data show that these strains have been detected globally and in many cases are associated with glycopeptide treatment failure; however, more rigorous clinical studies are required to clearly define the contribution of hVISA to glycopeptide treatment outcomes. It is now becoming clear that sequential point mutations in key global regulatory genes contribute to the hVISA and VISA phenotypes, which are associated predominately with cell wall thickening and restricted vancomycin access to its site of activity in the division septum; however, the phenotypic features of these strains can vary because the mutations leading to resistance can vary. Interestingly, changes in the staphylococcal surface and expression of agr are likely to impact host-pathogen interactions in hVISA and VISA infections. Given the subtleties of vancomycin susceptibility testing against S. aureus , it is imperative that diagnostic laboratories use well-standardized methods and have a framework for detecting reduced vancomycin susceptibility in S. aureus .

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1128/cmr.00042-09

Cites

405 of 405 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically
Ferraro, M. J. (2000) · Cited by 16,875
Staphylococcus aureus Infections
Lowy, F. D. (1998) · New England Journal of Medicine · doi:10.1056/nejm199808203390806 · Cited by 6,018
Invasive Methicillin-Resistant <EMPH TYPE="ITAL">Staphylococcus aureus</EMPH> Infections in the United States
Klevens, R. M. (2007) · JAMA · doi:10.1001/jama.298.15.1763 · Cited by 3,726
Osteomyelitis
Lew, D. P., & Waldvogel, F. A. (2004) · The Lancet · doi:10.1016/s0140-6736(04)16727-5 · Cited by 1,988
Methicillin-resistant Staphylococcus aureus clinical strain with reduced vancomycin susceptibility
Hiramatsu, K. (1997) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/40.1.135 · Cited by 1,984
Community-Acquired Methicillin-ResistantStaphylococcus aureusCarrying Panton-Valentine Leukocidin Genes: Worldwide Emergence
Vandenesch, F., Naimi, T. S., Enright, M. C., Lina, G., Nimmo, G. R., Heffernan, H., Liassine, N., Bes, M., Greenland, T., Reverdy, M. E., et al. (2003) · Emerging infectious diseases · doi:10.3201/eid0908.030089 · Cited by 1,718
Daptomycin versus Standard Therapy for Bacteremia and Endocarditis Caused by Staphylococcus aureus
Fowler, V. G., Boucher, H. W., Corey, G. R., Abrutyn, E., Karchmer, A. W., Rupp, M. E., Levine, D. P., Chambers, H. F., Tally, F. P., Vigliani, G. A., et al. (2006) · New England Journal of Medicine · doi:10.1056/nejmoa053783 · Cited by 1,459
The Changing Epidemiology of Staphylococcus aureus ?
Chambers, H. F. “. (2001) · Emerging infectious diseases · doi:10.3201/eid0702.010204 · Cited by 1,419
Plasmid-Mediated Resistance to Vancomycin and Teicoplanin in Enterococcus Faecium
Leclercq, R., Derlot, E., Duval, J., & Courvalin, P. M. (1988) · New England Journal of Medicine · doi:10.1056/nejm198807213190307 · Cited by 1,411
Survey of Infections Due to Staphylococcus Species: Frequency of Occurrence and Antimicrobial Susceptibility of Isolates Collected in the United States, Canada, Latin America, Europe, and the Western Pacific Region for the SENTRY Antimicrobial Surveillance Program, 1997–1999
Diekema, D. J., Pfaller, M. A., Schmitz, F., Smayevsky, J., Bell, J. M., Jones, R. N., Beach, M. L., & SENTRY Participants Group (2001) · Clinical Infectious Diseases · doi:10.1086/320184 · Cited by 1,363

Show all 406 references

Research works printed but not linked: 1

Ferraz, V., A. G. Duse, M. Kassel, A. D. Black, T. Ito, and K. Hiramatsu. 2000. Vancomycin-resistant Staphylococcus aureus occurs in South Africa. S. Afr. Med. J.90:1113.

Sorted by citations

Items 101–200 of 962

Targeting a cell wall biosynthesis hot spot
Müller, A., Klöckner, A., & Schneider, T. (2017) · Natural Product Reports · doi:10.1039/c7np00012j · Cited by 91
Two-Component Systems of S. aureus: Signaling and Sensing Mechanisms
Bleul, L., François, P., & Wolz, C. (2021) · Genes · doi:10.3390/genes13010034 · Cited by 89
Antimicrobial Resistance in the Intensive Care Unit: Mechanisms, Epidemiology, and Management of Specific Resistant Pathogens
Fraimow, H. S., & Tsigrelis, C. (2010) · Critical Care Clinics · doi:10.1016/j.ccc.2010.11.002 · Cited by 87
Performance of Various Testing Methodologies for Detection of Heteroresistant Vancomycin-Intermediate Staphylococcus aureus in Bloodstream Isolates
van Hal, S. J., Wehrhahn, M. C., Barbagiannakos, T., Mercer, J. L., Chen, D., Paterson, D. L., & Gosbell, I. B. (2011) · Journal of Clinical Microbiology · doi:10.1128/jcm.02302-10 · Cited by 88
Construction of poly (vinyl alcohol)/poly (lactide-glycolide acid)/vancomycin nanoparticles on titanium for enhancing the surface self-antibacterial activity and cytocompatibility
Liu, Z., Zhu, Y., Liu, X., Yeung, K., & Wu, S. (2016) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2016.12.016 · Cited by 87
Recent Advances in the Development of Semisynthetic Glycopeptide Antibiotics: 2014–2022
van Groesen, E., Innocenti, P., & Martin, N. I. (2022) · ACS Infectious Diseases · doi:10.1021/acsinfecdis.2c00253 · Cited by 89
Antibiotic heteroresistance in ESKAPE pathogens, from bench to bedside
Roch, M., Sierra, R., & Andrey, D. O. (2022) · Clinical Microbiology and Infection · doi:10.1016/j.cmi.2022.10.018 · Cited by 88
Virulence attributes of successful methicillin-resistant Staphylococcus aureus lineages
Jiang, J., Cameron, D. R., Nethercott, C., Aires-de-Sousa, M., & Peleg, A. Y. (2023) · Clinical Microbiology Reviews · doi:10.1128/cmr.00148-22 · Cited by 94
Clinical Outcomes in Patients with Heterogeneous Vancomycin-Intermediate Staphylococcus aureus Bloodstream Infection
Casapao, A. M., Leonard, S. N., Davis, S. L., Lodise, T. P., Patel, N., Goff, D. A., LaPlante, K. L., Potoski, B. A., & Rybak, M. J. (2013) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00380-13 · Cited by 85
Infections in Patients with Cystic Fibrosis
Gilligan, P. H. (2014) · Clinics in Laboratory Medicine · doi:10.1016/j.cll.2014.02.001 · Cited by 89
Modulating Activity of Vancomycin and Daptomycin on the Expression of Autolysis Cell-Wall Turnover and Membrane Charge Genes in hVISA and VISA Strains
Cafiso, V., Bertuccio, T., Spina, D., Purrello, S., Campanile, F., Pietro, C. D., Purrello, M., & Stefani, S. (2012) · PLoS ONE · doi:10.1371/journal.pone.0029573 · Cited by 84
Rising incidence of Staphylococcus aureus with reduced susceptibility to vancomycin and susceptibility to antibiotics: a global analysis 2004–2009
Hawser, S., Bouchillon, S. K., Hoban, D. J., Dowzicky, M. J., & Babinchak, T. (2011) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2010.10.029 · Cited by 82
Formulation of pH-responsive PEGylated nanoparticles with high drug loading capacity and programmable drug release for enhanced antibacterial activity
Li, D., Tang, G., Yao, H. Q., Zhu, Y., Shi, C., Fu, Q., Yang, F., & Wang, X. (2022) · Bioactive Materials · doi:10.1016/j.bioactmat.2022.02.018 · Cited by 86
Antimicrobial Properties of Capsaicin: Available Data and Future Research Perspectives
Periferakis, A.-T., Periferakis, A., Periferakis, K., Căruntu, A., Bădărău, I. A., Săvulescu-Fiedler, I., Scheau, C., & Căruntu, C. (2023) · Nutrients · doi:10.3390/nu15194097 · Cited by 92
Clinical, Epidemiological, and Laboratory Aspects of Methicillin-Resistant Staphylococcus aureus (MRSA) Infections
Palavecino, E. L. (2007) · Methods in molecular biology · doi:10.1007/978-1-59745-468-1_1 · Cited by 88
Biochemical and biophysical characterization of PlyGRCS, a bacteriophage endolysin active against methicillin-resistant Staphylococcus aureus
Linden, S. B., Zhang, H., Heselpoth, R. D., Shen, Y., Schmelcher, M., Eichenseher, F., & Nelson, D. C. (2014) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-014-5930-1 · Cited by 83
Controlled Delivery of Vancomycin via Charged Hydrogels
Gustafson, C. T., Boakye‐Agyeman, F., Brinkman, C. L., Reid, J. M., Patel, R., Bajzer, Ž., Dadsetan, M., & Yaszemski, M. J. (2016) · PLoS ONE · doi:10.1371/journal.pone.0146401 · Cited by 83
Are We Ready for Novel Detection Methods to Treat Respiratory Pathogens in Hospital-Acquired Pneumonia?
Endimiani, A., Hujer, K. M., Hujer, A. M., Kurz, S. G., Jacobs, M. R., Perlin, D. S., & Bonomo, R. A. (2011) · Clinical Infectious Diseases · doi:10.1093/cid/cir054 · Cited by 82
The cell wall precursor lipid II acts as a molecular signal for the Ser/Thr kinase PknB of Staphylococcus aureus
Hardt, P., Engels, I., Rausch, M. D., Gajdiss, M., Ulm, H., Saß, P., Ohlsen, K., Sahl, H., Bierbaum, G., Schneider, T., et al. (2016) · International Journal of Medical Microbiology · doi:10.1016/j.ijmm.2016.12.001 · Cited by 82
Relevance of vancomycin-intermediate susceptibility and heteroresistance in methicillin-resistant Staphylococcus aureus bacteraemia
Khatib, R., Jose, J., Musta, A. C., Sharma, M., Fakih, M. G., Johnson, L. B., RIEDERER, K. M., & Shemes, S. P. (2011) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkr169 · Cited by 81
Multifunctional Adhesive Hydrogels: From Design to Biomedical Applications
Tang, S., Feng, K., Yang, R., Yang, C., Chen, M., Zhang, H., Shi, N., Wei, Z., Ren, H. P., & Ma, Y. (2024) · Advanced Healthcare Materials · doi:10.1002/adhm.202403734 · Cited by 84
The Interface Between Antibiotic Resistance and Virulence in Staphylococcus aureus and Its Impact Upon Clinical Outcomes
Cameron, D. R., Howden, B. P., & Peleg, A. Y. (2011) · Clinical Infectious Diseases · doi:10.1093/cid/cir473 · Cited by 83
Self-citation
Emergence of Daptomycin Resistance in Daptomycin-Naïve Rabbits with Methicillin-Resistant Staphylococcus aureus Prosthetic Joint Infection Is Associated with Resistance to Host Defense Cationic Peptides and mprF Polymorphisms
Mishra, N. N., Yang, S., Chen, L., Muller‐Serieys, C., Saleh‐Mghir, A., Kuhn, S. M., Peschel, A., Yeaman, M. R., Nast, C. C., Kreiswirth, B. N., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0071151 · Cited by 81
Vancomycin Heteroresistance Is Associated with Reduced Mortality in ST239 Methicillin-Resistant Staphylococcus aureus Blood Stream Infections
van Hal, S. J., Jones, M., Gosbell, I. B., & Paterson, D. L. (2011) · PLoS ONE · doi:10.1371/journal.pone.0021217 · Cited by 79
Rapid Detection of Vancomycin-Intermediate Staphylococcus aureus by Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry
Mather, C. A., Werth, B. J., Sivagnanam, S., SenGupta, D. J., & Butler‐Wu, S. M. (2016) · Journal of Clinical Microbiology · doi:10.1128/jcm.02428-15 · Cited by 77
Mechanisms of antimicrobial resistance among hospital-associated pathogens
Khan, A., Miller, W. R., & Arias, C. A. (2018) · Expert Review of Anti-infective Therapy · doi:10.1080/14787210.2018.1456919 · Cited by 82
Genomic exploration of sequential clinical isolates reveals a distinctive molecular signature of persistent Staphylococcus aureus bacteraemia
Giulieri, S. G., Baines, S. L., Guérillot, R., Seemann, T., da Silva, A. G., Schultz, M. B., Massey, R. C., Holmes, N. E., Stinear, T. P., & Howden, B. P. (2018) · Genome Medicine · doi:10.1186/s13073-018-0574-x · Cited by 72
Self-citation
Treatment of Methicillin-Resistant Staphylococcus aureus: Vancomycin and Beyond
Holmes, N. E., Tong, S. Y. C., Davis, J. S., & van Hal, S. J. (2015) · Seminars in Respiratory and Critical Care Medicine · doi:10.1055/s-0034-1397040 · Cited by 76
Identification of an Antimicrobial Agent Effective against Methicillin-Resistant Staphylococcus aureus Persisters Using a Fluorescence-Based Screening Strategy
Kim, W., Conery, A. L., Rajamuthiah, R., Fuchs, B. B., Ausubel, F. M., & Mylonakis, E. E. (2015) · PLoS ONE · doi:10.1371/journal.pone.0127640 · Cited by 75
Comprehensive Identification of Mutations Responsible for Heterogeneous Vancomycin-Intermediate Staphylococcus aureus (hVISA)-to-VISA Conversion in Laboratory-Generated VISA Strains Derived from hVISA Clinical Strain Mu3
Matsuo, M., Cui, L., Kim, J., & Hiramatsu, K. (2013) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00425-13 · Cited by 75
Antibacterial Effects of Glycyrrhetinic Acid and Its Derivatives on Staphylococcus aureus
Oyama, K., Kawada-Matsuo, M., Oogai, Y., Hayashi, T., Nakamura, N., & Komatsuzawa, H. (2016) · PLoS ONE · doi:10.1371/journal.pone.0165831 · Cited by 75
Biofilm Formation by Pathogenic Bacteria: Applying a Staphylococcus aureus Model to Appraise Potential Targets for Therapeutic Intervention
Sedarat, Z., & Taylor-Robinson, A. W. (2022) · Pathogens · doi:10.3390/pathogens11040388 · Cited by 81
Missense Mutations in PBP2A Affecting Ceftaroline Susceptibility Detected in Epidemic Hospital-Acquired Methicillin-Resistant Staphylococcus aureus Clonotypes ST228 and ST247 in Western Switzerland Archived since 1998
Kelley, W. L., Jousselin, A., Barras, C., Lelong, E., & Renzoni, A. (2015) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.04068-14 · Cited by 74
Glycopeptide Antibiotics: Structure and Mechanisms of Action
Kang, H.-K., & Park, Y. (2015) · Journal of Bacteriology and Virology · doi:10.4167/jbv.2015.45.2.67 · Cited by 74
Spread of Epidemic MRSA-ST5-IV Clone Encoding PVL as a Major Cause of Community Onset Staphylococcal Infections in Argentinean Children
Sola, C., Paganini, H. R., Egea, A. L., Moyano, A. J., Garnero, A., Kevric, I., Culasso, C., Vindel, A., Study Group of CA-MRSA in Children, A.-2., Lopardo, H. Á., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0030487 · Cited by 72
Endophthalmitis caused by Gram-positive organisms with reduced vancomycin susceptibility: literature review and options for treatment
Relhan, N., Albini, T. A., Pathengay, A., Kuriyan, A. E., Miller, D., & Flynn, H. W. (2015) · British Journal of Ophthalmology · doi:10.1136/bjophthalmol-2015-307722 · Cited by 72
The Mechanism of Action of Lysobactin
Lee, W., Schaefer, K., Qiao, Y., Srisuknimit, V., Steinmetz, H., Müller, R., Kahne, D. E., & Walker, S. (2015) · Journal of the American Chemical Society · doi:10.1021/jacs.5b11807 · Cited by 72
Strain Dependent Genetic Networks for Antibiotic-Sensitivity in a Bacterial Pathogen with a Large Pan-Genome
van Opijnen, T., Dedrick, S., & Bento, J. (2016) · PLoS Pathogens · doi:10.1371/journal.ppat.1005869 · Cited by 72
Novel Combinations of Vancomycin plus Ceftaroline or Oxacillin against Methicillin-Resistant Vancomycin-Intermediate Staphylococcus aureus (VISA) and Heterogeneous VISA
Werth, B. J., Vidaillac, C., Murray, K. P., Newton, K. L., Sakoulas, G., Nonejuie, P., Pogliano, J., & Rybak, M. J. (2013) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.02354-12 · Cited by 69
Convergent Evolution Driven by Rifampin Exacerbates the Global Burden of Drug-Resistant Staphylococcus aureus
Guérillot, R., da Silva, A. G., Monk, I. R., Giulieri, S. G., Tomita, T., Alison, E., Porter, J., Pidot, S. J., Gao, W., Peleg, A. Y., et al. (2018) · mSphere · doi:10.1128/msphere.00550-17 · Cited by 71
Self-citation
Methicillin-Resistant Staphylococcus Aureus Infections
Taylor, A. R. (2013) · Primary Care Clinics in Office Practice · doi:10.1016/j.pop.2013.06.002 · Cited by 69
Bio-inspired resin acid-derived materials as anti-bacterial resistance agents with unexpected activities
Ganewatta, M. S., Chen, Y. P., Wang, J., Zhou, J., Ebalunode, J. O., Nagarkatti, M., Decho, A. W., & Tang, C. (2014) · Chemical Science · doi:10.1039/c4sc00034j · Cited by 69
Vancomycin therapeutics and monitoring: a contemporary approach
Avent, M. L., Vaska, V. L., Rogers, B. A., Cheng, A. C., van Hal, S. J., Holmes, N. E., Howden, B. P., & Paterson, D. L. (2012) · Internal Medicine Journal · doi:10.1111/imj.12036 · Cited by 68
Self-citation
Whole Genome Sequencing and Complete Genetic Analysis Reveals Novel Pathways to Glycopeptide Resistance in Staphylococcus aureus
Renzoni, A., Andrey, D. O., Jousselin, A., Barras, C., Monod, A., Vaudaux, P. E., Lew, D., & Kelley, W. L. (2011) · PLoS ONE · doi:10.1371/journal.pone.0021577 · Cited by 68
Total Syntheses and Initial Evaluation of [Ψ[C(═S)NH]Tpg4]vancomycin, [Ψ[C(═NH)NH]Tpg4]vancomycin, [Ψ[CH2NH]Tpg4]vancomycin, and Their (4-Chlorobiphenyl)methyl Derivatives: Synergistic Binding Pocket and Peripheral Modifications for the Glycopeptide Antibiotics
Okano, A., Nakayama, A., Wu, K., Lindsey, E. A., Schammel, A. W., Feng, Y., Collins, K. C., & Boger, D. L. (2015) · Journal of the American Chemical Society · doi:10.1021/jacs.5b01008 · Cited by 68
Reversible Antibiotic Tolerance Induced in Staphylococcus aureus by Concurrent Drug Exposure
Haaber, J., Friberg, C., McCreary, M., Lin, R., Cohen, S. N., & Ingmer, H. (2015) · mBio · doi:10.1128/mbio.02268-14 · Cited by 68
Daptomycin Resistance in Clinical MRSA Strains Is Associated with a High Biological Fitness Cost
Roch, M., Gagetti, P. S., Davis, J. J., Ceriana, P., Errecalde, L., Corso, A. C., & Rosato, A. E. (2017) · Frontiers in Microbiology · doi:10.3389/fmicb.2017.02303 · Cited by 67
Rapid antibiotic susceptibility phenotypic characterization of Staphylococcus aureus using automated microscopy of small numbers of cells
Price, C. S., Kon, S. E., & Metzger, S. W. (2014) · Journal of Microbiological Methods · doi:10.1016/j.mimet.2013.12.021 · Cited by 66
VanA and VanB Positive Vancomycin-resistant Staphylococcus aureus Among Clinical Isolates in Shiraz, South of Iran
Saadat, S., Solhjoo, K., Norouz-nejad, M., & Kazemi, A. (2014) · Oman Medical Journal · doi:10.5001/omj.2014.90 · Cited by 69
Current strategies against multidrug-resistant Staphylococcus aureus and advances toward future therapy
Kumar, S., Mahato, R. P., Ch, S., & Kumbham, S. (2025) · The Microbe · doi:10.1016/j.microb.2025.100281 · Cited by 73
Is Vancomycin MIC “Creep” Method Dependent? Analysis of Methicillin-Resistant Staphylococcus aureus Susceptibility Trends in Blood Isolates from North East Scotland from 2006 to 2010
Edwards, B., Milne, K., Lawes, T., Cook, I., Robb, A., & Gould, I. M. (2011) · Journal of Clinical Microbiology · doi:10.1128/jcm.05520-11 · Cited by 65
Docking on Lipid II—A Widespread Mechanism for Potent Bactericidal Activities of Antibiotic Peptides
Grein, F., Schneider, T., & Sahl, H. (2019) · Journal of Molecular Biology · doi:10.1016/j.jmb.2019.05.014 · Cited by 72
Decreased Vancomycin Susceptibility in Staphylococcus aureus Caused by IS 256 Tempering of WalKR Expression
McEvoy, C. R. E., Tsuji, B. T., Gao, W., Seemann, T., Porter, J. L., Doig, K., Ngo, D. T., Howden, B. P., & Stinear, T. P. (2013) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00279-13 · Cited by 64
Self-citation
Focused review on dual inhibition of quorum sensing and efflux pumps: A potential way to combat multi drug resistant Staphylococcus aureus infections
Kaur, B., Gupta, J., Sharma, S., Sharma, D., & Sharma, S. (2021) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2021.08.199 · Cited by 63
The Posttranslocational Chaperone Lipoprotein PrsA Is Involved in both Glycopeptide and Oxacillin Resistance in Staphylococcus aureus
Jousselin, A., Renzoni, A., Andrey, D. O., Monod, A., Lew, D. P., & Kelley, W. L. (2012) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.06264-11 · Cited by 63
Clinical characteristics and therapeutic outcomes of hematogenous vertebral osteomyelitis caused by methicillin-resistant Staphylococcus aureus
Park, K., Chong, Y. P., Kim, S., Lee, S., Choi, S., Lee, M. S., Jeong, J., Woo, J. H., & Kim, Y. S. (2013) · Journal of Infection · doi:10.1016/j.jinf.2013.07.026 · Cited by 63
Peptide Biomarker Discovery for Identification of Methicillin-Resistant and Vancomycin-Intermediate Staphylococcus aureus Strains by MALDI-TOF
Lu, J., Tsai, F., Ho, C., Liu, Y.-C., & Chen, C. (2012) · Analytical Chemistry · doi:10.1021/ac300855z · Cited by 63
A Highly Potent Antibacterial Agent Targeting Methicillin-Resistant Staphylococcus aureus Based on Cobalt Bis(1,2-Dicarbollide) Alkoxy Derivative
Zheng, Y., Liu, W., Chen, Y., Jiang, H., Yan, H., Kosenko, I. D., Chekulaeva, L. A., Sivaev, I. B., Bregadze, V. I., & Wang, X. (2017) · Organometallics · doi:10.1021/acs.organomet.7b00426 · Cited by 63
dltA overexpression: A strain-independent keystone of daptomycin resistance in methicillin-resistant Staphylococcus aureus
Cafiso, V., Bertuccio, T., Purrello, S., Campanile, F., Mammina, C., Sartor, A., Raglio, A., & Stefani, S. (2013) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2013.10.001 · Cited by 62
Antibiotic Resistance Pattern of Methicillin Resistant and Methicillin Sensitive Staphylococcus aureus Isolates in Tehran, Iran
Rahimi, F., Bouzari, M., Katouli, M., & Pourshafie, M. R. (2012) · Jundishapur Journal of Microbiology · doi:10.5812/jjm.4896 · Cited by 62
In vitro antibacterial effects of Tanreqing injection combined with vancomycin or linezolid against methicillin-resistant Staphylococcus aureus
Yang, W., Liu, J., Blažeković, B., Sun, Y., Ma, S., Ren, C., Vladimir‐Knežević, S., Li, C., Xing, Y., Tian, G., et al. (2018) · BMC Complementary and Alternative Medicine · doi:10.1186/s12906-018-2231-8 · Cited by 62
Phenotypic and molecular identification of vancomycin resistance in clinical Staphylococcus aureus isolates in Osogbo, Nigeria
Bamigboye, B. T., Olowe, O. A., & Taiwo, S. S. (2018) · European Journal of Microbiology and Immunology · doi:10.1556/1886.2018.00003 · Cited by 61
Additional Routes to Staphylococcus aureus Daptomycin Resistance as Revealed by Comparative Genome Sequencing, Transcriptional Profiling, and Phenotypic Studies
Song, Y., Rubio, A., Jayaswal, R. K., Silverman, J. A., & Wilkinson, B. J. (2013) · PLoS ONE · doi:10.1371/journal.pone.0058469 · Cited by 61
Peptides As The Next Generation of Anti-Infectives
Mercer, D. K., & O′Neil, D. A. (2013) · Future Medicinal Chemistry · doi:10.4155/fmc.12.213 · Cited by 61
Rapid Detection of Heterogeneous Vancomycin-Intermediate Staphylococcus aureus Based on Matrix-Assisted Laser Desorption Ionization Time-of-Flight: Using a Machine Learning Approach and Unbiased Validation
Wang, H., Chen, C., Lee, T.-Y., Horng, J., Liu, T.-P., Tseng, Y., & Lu, J. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.02393 · Cited by 62
Vancomycin Minimum Inhibitory Concentration and Outcome in Patients With Staphylococcus aureus Bacteremia: Pearl or Pellet?
Holland, T. L., & Fowler, V. G. (2011) · The Journal of Infectious Diseases · doi:10.1093/infdis/jir275 · Cited by 60
Staphylococcus aureus Induced Wound Infections Which Antimicrobial Resistance, Methicillin- and Vancomycin-Resistant: Assessment of Emergence and Cross Sectional Study
Almuhayawi, M. S., Alruhaili, M. H., Gattan, H. S., Alharbi, M. T., Nagshabandi, M. K., Jaouni, S. K. A., Selim, S., Alanazi, A., Alruwaili, Y. S., Faried, O. A., et al. (2023) · Infection and Drug Resistance · doi:10.2147/idr.s418681 · Cited by 62
Molecular characteristics and virulence factors in methicillin-susceptible, resistant, and heterogeneous vancomycin-intermediate Staphylococcus aureus from central-southern China
Liu, C., Chen, Z., Sun, Z., Feng, X., Zou, M., Cao, W., Wang, S., Zeng, J., Wang, Y., & Sun, M. (2014) · Journal of Microbiology Immunology and Infection · doi:10.1016/j.jmii.2014.03.003 · Cited by 61
Treatment of bacteraemia: meticillin-resistant Staphylococcus aureus (MRSA) to vancomycin-resistant S. aureus (VRSA)
Gould, I. M. (2013) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2013.04.006 · Cited by 60
Diagnosis and treatment of bacteremia and endocarditis due to Staphylococcus aureus. A clinical guideline from the Spanish Society of Clinical Microbiology and Infectious Diseases (SEIMC)
Gudiol, F., Aguado, J. M., Almirante, B., Bouza, E., Cercenado, E., Domínguez, M. Á., Gasch, O., Lora-Tamayo, J., Miró, J. M., Palomar, M., et al. (2015) · Enfermedades Infecciosas y Microbiología Clínica · doi:10.1016/j.eimc.2015.03.015 · Cited by 59
The burden of multidrug-resistant organisms on tertiary hospitals posed by patients with recent stays in long-term acute care facilities
Marchaim, D., Chopra, T., Bogan, C., Bheemreddy, S., Sengstock, D. M., Jagarlamudi, R., Malani, A. N., Lemanek, L., Moshos, J. A., Lephart, P., et al. (2012) · American Journal of Infection Control · doi:10.1016/j.ajic.2011.09.011 · Cited by 59
Telavancin for Hospital-Acquired Pneumonia: Clinical Response and 28-Day Survival
Corey, G. R., Kollef, M. H., Shorr, A. F., Rubinstein, E., Stryjewski, M. E., Hopkins, A., & Barriere, S. L. (2014) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.02330-13 · Cited by 58
Molecular Basis of Non-β-Lactam Antibiotics Resistance in Staphylococcus aureus
Lade, H. S., Joo, H., & Kim, J. (2022) · Antibiotics · doi:10.3390/antibiotics11101378 · Cited by 64
Susceptibility trends including emergence of linezolid resistance among coagulase-negative staphylococci and meticillin-resistant Staphylococcus aureus from invasive infections
Decousser, J., Desroches, M., Bourgeois‐Nicolaos, N., Potier, J., Jehl, F., Lina, G., Cattoir, V., Vandenesch, F., & Doucet‐Populaire, F. (2015) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2015.07.022 · Cited by 58
Biodegradable Antimicrobial Polycarbonates with In Vivo Efficacy against Multidrug‐Resistant MRSA Systemic Infection
Cheng, J., Chin, W., Dong, H., Xu, L., Zhong, G., Huang, Y., Li, L., Xu, K., Wu, M., Hedrick, J. L., et al. (2015) · Advanced Healthcare Materials · doi:10.1002/adhm.201500471 · Cited by 58
A Mutation in the PP2C Phosphatase Gene in a Staphylococcus aureus USA300 Clinical Isolate with Reduced Susceptibility to Vancomycin and Daptomycin
Passalacqua, K. D., Satola, S. W., Crispell, E. K., & Read, T. D. (2012) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.05770-11 · Cited by 56
Light-Excited Antibiotics for Potentiating Bacterial Killing via Reactive Oxygen Species Generation
Jiang, Q., Fangjie, E., Tian, J., Yang, J.-T., Zhang, J., & Cheng, Y. (2020) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.0c02647 · Cited by 58
Thioridazine Induces Major Changes in Global Gene Expression and Cell Wall Composition in Methicillin-Resistant Staphylococcus aureus USA300
Thorsing, M., Klitgaard, J. K., Atilano, M. L., Skov, M. N., Kolmos, H. J., Filipe, S. R., & Kallipolitis, B. H. (2013) · PLoS ONE · doi:10.1371/journal.pone.0064518 · Cited by 57
Silver-doped bioactive glass particles for in vivo bone tissue regeneration and enhanced methicillin-resistant Staphylococcus aureus (MRSA) inhibition
Pajares‐Chamorro, N., Wagley, Y., Maduka, C. V., Youngstrom, D. W., Yeger, A., Badylak, S. F., Hammer, N. D., Hankenson, K. D., & Chatzistavrou, X. (2020) · Materials Science and Engineering C · doi:10.1016/j.msec.2020.111693 · Cited by 57
Clinical Implications of Vancomycin Heteroresistant and Intermediately Susceptible S taphylococcus aureus
Gomes, D. M., Ward, K. E., & LaPlante, K. L. (2015) · Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy · doi:10.1002/phar.1577 · Cited by 57
Detection of Intermediately Vancomycin-Susceptible and Heterogeneous Staphylococcus aureus Isolates: Comparison of Etest and Agar Screening Methods
RIEDERER, K. M., Shemes, S. P., Chase, P., Musta, A. C., mar, A. É., & Khatib, R. (2011) · Journal of Clinical Microbiology · doi:10.1128/jcm.01435-10 · Cited by 57
Comparison of the clinical features, bacterial genotypes and outcomes of patients with bacteraemia due to heteroresistant vancomycin-intermediate Staphylococcus aureus and vancomycin-susceptible S. aureus
Park, K.-H., Kim, E. S., Kim, H.-S., Park, S. J., Bang, K. M., Park, H. J., Park, S.-Y., Moon, S. M., Chong, Y. P., Kim, S., et al. (2012) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dks131 · Cited by 56
Right-Sided Infective Endocarditis and Pulmonary Infiltrates
Chahoud, J., Sharif-Yakan, A., Saad, H. A., & Kanj, S. S. (2015) · Cardiology in Review · doi:10.1097/crd.0000000000000095 · Cited by 56
Epidemiology and clinical relevance of microbial resistance determinants versus anti-Gram-positive agents
Rossolini, G. M., Mantengoli, E., Montagnani, F., & Pollini, S. (2010) · Current Opinion in Microbiology · doi:10.1016/j.mib.2010.08.006 · Cited by 55
Detection of Staphylococcus aureus Isolates with Heterogeneous Intermediate-Level Resistance to Vancomycin in the United States
Richter, S. S., Satola, S. W., Crispell, E. K., Heilmann, K. P., Dohrn, C. L., Riahi, F., Costello, A. J., Diekema, D. J., & Doern, G. V. (2011) · Journal of Clinical Microbiology · doi:10.1128/jcm.01152-11 · Cited by 55
Genomic Insights Into Last-Line Antimicrobial Resistance in Multidrug-Resistant Staphylococcus and Vancomycin-Resistant Enterococcus
Turner, A. M., Lee, J. Y. H., Gorrie, C. L., Howden, B. P., & Carter, G. P. (2021) · Frontiers in Microbiology · doi:10.3389/fmicb.2021.637656 · Cited by 61
Self-citation
In Vitro Susceptibilities and Molecular Analysis of Vancomycin-Intermediate and Vancomycin-Resistant Staphylococcus aureus Isolates
Saravolatz, L. D., Pawlak, J., & Johnson, L. B. (2012) · Clinical Infectious Diseases · doi:10.1093/cid/cis492 · Cited by 53
Structural Variations of the Cell Wall Precursor Lipid II and Their Influence on Binding and Activity of the Lipoglycopeptide Antibiotic Oritavancin
Münch, D., Engels, I., Müller, A., Reder-Christ, K., Falkenstein‐Paul, H., Bierbaum, G., Grein, F., Bendas, G., Sahl, H., & Schneider, T. (2014) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.02663-14 · Cited by 53
Daptomycin Resistant Staphylococcus aureus Clinical Strain With Novel Non-synonymous Mutations in the mprF and vraS Genes: A New Insight Into Daptomycin Resistance
Sabat, A. J., Tinelli, M., Grundmann, H., Akkerboom, V., Monaco, M., Grosso, M. D., Errico, G., Pantosti, A., & Friedrich, A. W. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.02705 · Cited by 53
Thymol Mediates Bactericidal Activity against Staphylococcus aureus by Targeting an Aldo–Keto Reductase and Consequent Depletion of NADPH
Zhou, W., Wang, Z., Mo, H., Zhao, Y., Li, H., Zhang, H., Hu, L., & Zhou, X. (2019) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.9b03517 · Cited by 54
In Vivo Efficacy of a “Smart” Antimicrobial Implant Coating
Stavrakis, A. I., Zhu, S., Hegde, V. V., Loftin, A. H., Ashbaugh, A. G., Niska, J. A., Miller, L. S., Segura, T., & Bernthal, N. M. (2016) · Journal of Bone and Joint Surgery · doi:10.2106/jbjs.15.01273 · Cited by 52
Vancomycin susceptibility in methicillin-resistant Staphylococcus aureus is mediated by YycHI activation of the WalRK essential two-component regulatory system
Cameron, D. R., Jiang, J., Kostoulias, X., Foxwell, D. J., & Peleg, A. Y. (2016) · Scientific Reports · doi:10.1038/srep30823 · Cited by 52
Evaluation of Ceftaroline Alone and in Combination against Biofilm-Producing Methicillin-Resistant Staphylococcus aureus with Reduced Susceptibility to Daptomycin and Vancomycin in an In Vitro Pharmacokinetic/Pharmacodynamic Model
Barber, K. E., Smith, J. R., Ireland, C. E., Boles, B. R., Rose, W. E., & Rybak, M. J. (2015) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00386-15 · Cited by 51
The Staphylococcus aureus Thiol/Oxidative Stress Global Regulator Spx Controls trfA , a Gene Implicated in Cell Wall Antibiotic Resistance
Jousselin, A., Kelley, W. L., Barras, C., Lew, D. P., & Renzoni, A. (2013) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00220-13 · Cited by 51
Underestimation of Vancomycin and Teicoplanin MICs by Broth Microdilution Leads to Underdetection of Glycopeptide-Intermediate Isolates of Staphylococcus aureus
Vaudaux, P. E., Huggler, E., Bernard, L., Ferry, T., Renzoni, A., & Lew, D. P. (2010) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00269-10 · Cited by 52
β-Lactam Combinations with Vancomycin Show Synergistic Activity against Vancomycin-Susceptible Staphylococcus aureus, Vancomycin-Intermediate S. aureus (VISA), and Heterogeneous VISA
Tran, N. N., & Rybak, M. J. (2018) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00157-18 · Cited by 52
Current Perspectives on Treatment of Gram-Positive Infections in India: What Is the Way Forward?
Kulkarni, A. P., Nagvekar, V. C., Veeraraghavan, B., Warrier, A. R., Ts, D., Ahdal, J., & Jain, R. (2019) · Interdisciplinary Perspectives on Infectious Diseases · doi:10.1155/2019/7601847 · Cited by 50
Zinc-binding to the cytoplasmic PAS domain regulates the essential WalK histidine kinase of Staphylococcus aureus
Monk, I. R., Shaikh, N. H., Neville, S. L., Gajdiss, M., Sharkey, L. K. R., Lee, J. Y. H., Pidot, S. J., Seemann, T., Kuiper, M. J., Winnen, B., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-10932-4 · Cited by 50
Self-citation
Global Priority Pathogens: Virulence, Antimicrobial Resistance and Prospective Treatment Options
Campos, J. C. D. M., Antunes, L. C. M., & Ferreira, R. B. R. (2020) · Future Microbiology · doi:10.2217/fmb-2019-0333 · Cited by 52
Chelation in Antibacterial Drugs: From Nitroxoline to Cefiderocol and Beyond
Antić, D. R., Parčina, M., Gobin, I., & Didović, M. P. (2022) · Antibiotics · doi:10.3390/antibiotics11081105 · Cited by 52

Authors: Howden, B. P., Davies, J. K., Johnson, P. D. R., Stinear, T. P., & Grayson, M. L.
Affiliations: The University of Melbourne (AU)
Monash University (AU)
ORCID: Howden, Benjamin P.
Johnson, Paul D. R.
Stinear, Timothy P.
Venue: Clinical Microbiology Reviews
Publisher: American Society for Microbiology
Published: 2010-01
Volume: 23
Issue: 1
Pages: 99-139
ISSN: 0893-8512 (ISSN-L)
1098-6618
DOI: 10.1128/cmr.00042-09
PMC: PMC2806658
OpenAlex: W2126915534
Cited by: 962
References: 406
Citations by year: 2026: 42 · 2025: 41 · 2024: 48 · 2023: 58 · 2022: 45 · 2021: 52 · 2020: 49 · 2019: 60 · 2018: 54 · 2017: 51 · 2016: 63 · 2015: 83 · 2014: 69 · 2013: 88 · 2012: 72
FWCI: 9.15
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: journals.asm.org/non-commercial-tdm-license (tdm)
Locations: Clinical Microbiology Reviews (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Infectious Diseases › Antimicrobial Resistance in Staphylococcus
Health Sciences › Medicine › Microbiology (medical) › Antibiotic Resistance in Bacteria
Health Sciences › Medicine › Infectious Diseases › Antibiotic Use and Resistance
Keywords: vancomycin-intermediate Staphylococcus aureus, heterogeneous vancomycin-intermediate Staphylococcus aureus, reduced vancomycin susceptibility, glycopeptide resistance, cell wall thickening, agr gene, vancomycin susceptibility testing, treatment failure, host-pathogen interaction
MeSH terms: Anti-Bacterial Agents, Humans, Microbial Sensitivity Tests, Staphylococcal Infections, Staphylococcus aureus, Vancomycin, Treatment Outcome, Vancomycin Resistance

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Reduced Vancomycin Susceptibility in Staphylococcus aureus , Including Vancomycin-Intermediate and Heterogeneous Vancomycin-Intermediate Strains: Resistance Mechanisms, Laboratory Detection, and Clinical Implications

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks