The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Fosfomycin
Open accessAbstract
SUMMARY: The treatment of bacterial infections suffers from two major problems: spread of multidrug-resistant (MDR) or extensively drug-resistant (XDR) pathogens and lack of development of new antibiotics active against such MDR and XDR bacteria. As a result, physicians have turned to older antibiotics, such as polymyxins, tetracyclines, and aminoglycosides. Lately, due to development of resistance to these agents, fosfomycin has gained attention, as it has remained active against both Gram-positive and Gram-negative MDR and XDR bacteria. New data of higher quality have become available, and several issues were clarified further. In this review, we summarize the available fosfomycin data regarding pharmacokinetic and pharmacodynamic properties, the in vitro activity against susceptible and antibiotic-resistant bacteria, mechanisms of resistance and development of resistance during treatment, synergy and antagonism with other antibiotics, clinical effectiveness, and adverse events. Issues that need to be studied further are also discussed.
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Cites
Gupta, K., Hooton, T. M., Naber, K. G., Wullt, B., Colgan, R., Miller, L. G., Moran, G. J., Nicolle, L. E., Raz, R., Schaeffer, A. J., et al. (2011) · Clinical Infectious Diseases · doi:10.1093/cid/ciq257 · Cited by 3,038
Cited by
Antimicrobial Resistance in ESKAPE Pathogens
De Oliveira, D. M. P., Forde, B. M., Kidd, T. J., Harris, P. N. A., Schembri, M. A., Beatson, S. A., Paterson, D. L., & Walker, M. J. (2020) · Clinical Microbiology Reviews · doi:10.1128/cmr.00181-19 · Cited by 2,078
Vardakas, K. Z., Voulgaris, G. L., Maliaros, A., Samonis, G., & Falagas, M. E. (2018) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(17)30615-1 · Cited by 327
Self-citationFosfomycin: Mechanism and Resistance
Silver, L. L. (2017) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a025262 · Cited by 320
Koopmans, M. M., Brouwer, M. C., Vázquez-Boland, J. A., & van de Beek, D. (2023) · Clinical Microbiology Reviews · doi:10.1128/cmr.00060-19 · Cited by 293
Wright, H., Bonomo, R. A., & Paterson, D. L. (2017) · Clinical Microbiology and Infection · doi:10.1016/j.cmi.2017.09.001 · Cited by 256
Metadata
- Authors
- Falagas, M. E., Vouloumanou, E. K., Samonis, G., & Vardakas, K. Z.
- Venue
- Clinical Microbiology Reviews
- Publisher
- American Society for Microbiology
- Published
- 2016-04
- Volume
- 29
- Issue
- 2
- Pages
- 321-347
- ISSN
- 0893-8512 (ISSN-L)
- 1098-6618
- OpenAlex
- W4211238209
- Cited by
- 612
- References
- 1
- FWCI
- 20.28
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Falagas, M. E., Vouloumanou, E. K., Samonis, G., & Vardakas, K. Z. (2016). Fosfomycin. Clinical Microbiology Reviews. https://doi.org/10.1128/cmr.00068-15
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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