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Cited by 435

The DOI matches its Crossref record; 197 of the 197 references it cites were found in a registry or an index.

Molecular Basis of the Interaction of Salmonella with the Intestinal Mucosa

Open access
Darwin, K. Heran, Miller, Virginia L.·1999·Clinical Microbiology Reviews

Abstract

SUMMARY: Salmonella is one of the most extensively characterized bacterial pathogens and is a leading cause of bacterial gastroenteritis. Despite this, we are only just beginning to understand at a molecular level how Salmonella interacts with its mammalian hosts to cause disease. Studies during the past decade on the genetic basis of virulence of Salmonella have significantly advanced our understanding of the molecular basis of the host-pathogen interaction, yet many questions remain. In this review, we focus on the interaction of enterocolitis-causing salmonellae with the intestinal mucosa, since this is the initiating step for most infections caused by Salmonella. Animal and in vitro cell culture models for the interaction of these bacteria with the intestinal epithelium are reviewed, along with the bacterial genes that are thought to affect this interaction. Lastly, recent studies on the response of epithelial cells to Salmonella infection and how this might promote diarrhea are discussed.

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Crossref · 10.1128/cmr.12.3.405

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Metadata

Authors
Darwin, K. H., & Miller, V. L.
Venue
Clinical Microbiology Reviews
Published
1999-07
Volume
12
Issue
3
Pages
405-428
ISSN
  • 0893-8512 (ISSN-L)
  • 1098-6618
OpenAlex
W2260017570
Cited by
435
References
197
FWCI
42.45
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Molecular Basis of the Interaction of Salmonella with the Intestinal Mucosa. https://app.cochat.ai/papers/10.1128/cmr.12.3.405
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Darwin, K. H., & Miller, V. L. (1999). Molecular Basis of the Interaction of Salmonella with the Intestinal Mucosa. Clinical Microbiology Reviews. https://doi.org/10.1128/cmr.12.3.405

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.