The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Herpes Simplex Virus Resistance to Acyclovir and Penciclovir after Two Decades of Antiviral Therapy
Open accessAbstract
SUMMARY: Acyclovir, penciclovir, and their prodrugs have been widely used during the past two decades for the treatment of herpesvirus infections. In spite of the distribution of over 2.3 × 10 6 kg of these nucleoside analogues, the prevalence of acyclovir resistance in herpes simplex virus isolates from immunocompetent hosts has remained stable at approximately 0.3%. In immuncompromised patients, in whom the risk for developing resistance is much greater, the prevalence of resistant virus has also remained stable but at a higher level, typically 4 to 7%. These observations are examined in the light of characteristics of the virus, the drugs, and host factors.
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Cites
Diaz-Mitoma, F. (1998) · JAMA · doi:10.1001/jama.280.10.887 · Cited by 147
Cited by
Approved Antiviral Drugs over the Past 50 Years
De Clercq, E., & Li, G. (2016) · Clinical Microbiology Reviews · doi:10.1128/cmr.00102-15 · Cited by 1,430
Once-daily valacyclovir to reduce the risk of transmission of genital herpes.
Corey, L., Wald, A., Patel, R., Sacks, S. L., Tyring, S. K., Warren, T., Douglas, J. M., Paavonen, J., Morrow, R. A., Beutner, K. R., et al. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa035144 · Cited by 720
Gupta, R., Warren, T., & Wald, A. (2007) · The Lancet · doi:10.1016/s0140-6736(07)61908-4 · Cited by 599
Corey, L., Wald, A., Celum, C. L., & Quinn, T. C. (2004) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/00126334-200404150-00001 · Cited by 558
Resistance of Herpes Simplex Viruses to Nucleoside Analogues: Mechanisms, Prevalence, and Management
Piret, J., & Boivin, G. (2011) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00615-10 · Cited by 558
Metadata
- Authors
- Bacon, T. H., Levin, M. J., Leary, J. J., Sarisky, R. T., & Sutton, D.
- Venue
- Clinical Microbiology Reviews
- Publisher
- American Society for Microbiology
- Published
- 2003-01
- Volume
- 16
- Issue
- 1
- Pages
- 114-128
- ISSN
- 0893-8512 (ISSN-L)
- 1098-6618
- OpenAlex
- W2162317223
- Cited by
- 504
- References
- 1
- FWCI
- 10.09
- Type
- journal article
- Language
- en
- Open access
- green
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- Bacon, T. H., Levin, M. J., Leary, J. J., Sarisky, R. T., & Sutton, D. (2003). Herpes Simplex Virus Resistance to Acyclovir and Penciclovir after Two Decades of Antiviral Therapy. Clinical Microbiology Reviews. https://doi.org/10.1128/cmr.16.1.114-128.2003
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
