The DOI matches its Crossref record; 305 of the 305 references it cites were found in a registry or an index.
Clinical Microbiology of Bacterial and Fungal Sepsis in Very-Low-Birth-Weight Infants
Open accessAbstract
SUMMARY: Twenty percent of very-low-birth-weight (<1500 g) preterm infants experience a serious systemic infection, and despite advances in neonatal intensive care and antimicrobials, mortality is as much as threefold higher for these infants who develop sepsis than their counterparts without sepsis during their hospitalization. Outcomes may be improved by preventative strategies, earlier and accurate diagnosis, and adjunct therapies to combat infection and protect the vulnerable preterm infant during an infection. Earlier diagnosis on the basis of factors such as abnormal heart rate characteristics may offer the ability to initiate treatment prior to the onset of clinical symptoms. Molecular and adjunctive diagnostics may also aid in diagnosing invasive infection when clinical symptoms indicate infection but no organisms are isolated in culture. Due to the high morbidity and mortality, preventative and adjunctive therapies are needed. Prophylaxis has been effective in preventing early-onset group B streptococcal sepsis and late-onset Candida sepsis. Future research in prophylaxis using active and passive immunization strategies offers prevention without the risk of resistance to antimicrobials. Identification of the differences in neonatal intensive care units with low and high infection rates and implementation of infection control measures remain paramount in each neonatal intensive care unit caring for preterm infants.
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Cites
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Cited by
Invasive Fungal Pathogens: Current Epidemiological Trends
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Risk factors for candidemia in critically ill infants: a matched case-control study.
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What helps the mother of a preterm infant become securely attached, responsive and well-adjusted?
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Metadata
- Authors
- Kaufman, D., & Fairchild, K. D.
- Venue
- Clinical Microbiology Reviews
- Publisher
- American Society for Microbiology
- Published
- 2004-07
- Volume
- 17
- Issue
- 3
- Pages
- 638-680
- ISSN
- 0893-8512 (ISSN-L)
- 1098-6618
- OpenAlex
- W2126991340
- Cited by
- 435
- References
- 305
- FWCI
- 16.60
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: Clinical Microbiology of Bacterial and Fungal Sepsis in Very-Low-Birth-Weight Infants. https://app.cochat.ai/papers/10.1128/cmr.17.3.638-680.2004
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- Kaufman, D., & Fairchild, K. D. (2004). Clinical Microbiology of Bacterial and Fungal Sepsis in Very-Low-Birth-Weight Infants. Clinical Microbiology Reviews. https://doi.org/10.1128/cmr.17.3.638-680.2004
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
