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Bacterial spores and chemical sporicidal agents
Open accessAbstract
Bacterial spores are among the most resistant of all living cells to biocides, although the response depends on the stage of sporulation. The development of resistance to some agents such as chlorhexidine occurs much earlier in sporulation than does resistance to glutaraldehyde, which is a very late event. During germination or outgrowth or both, resistance is lost and the cells become as susceptible to biocides as nonsporulating bacteria. Mechanisms of spore resistance to, and the action of, biocides are discussed, and possible means of enhancing antispore activity are considered. The clinical and other uses of sporicidal and sporostatic chemical agents are described.
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Cited by
APIC guideline for selection and use of disinfectants
Rutala, W. A. (1996) · American Journal of Infection Control · doi:10.1016/s0196-6553(96)90066-8 · Cited by 459
Efficacy of “sporicidal” wipes against Clostridium difficile
Siani, H., Cooper, C., & Maillard, J.-Y. (2011) · American Journal of Infection Control · doi:10.1016/j.ajic.2011.01.006 · Cited by 66
Metadata
- Authors
- Russell, A. D.
- Venue
- Clinical Microbiology Reviews
- Publisher
- American Society for Microbiology
- Published
- 1990-04
- Volume
- 3
- Issue
- 2
- Pages
- 99-119
- ISSN
- 0893-8512 (ISSN-L)
- 1098-6618
- OpenAlex
- W2163971377
- Cited by
- 374
- References
- 0
- FWCI
- 4.09
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Russell, A. D. (1990). Bacterial spores and chemical sporicidal agents. Clinical Microbiology Reviews. https://doi.org/10.1128/cmr.3.2.99
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.