A two-hybrid screen of the yeast proteome for Hsp90 interactors uncovers a novel Hsp90 chaperone requirement in the activity of a stress-activated mitogen-activated protein kinase, Slt2p (Mpk1p).
Millson, Stefan H., Truman, Andrew W., King, Victoria, Prodromou, Chrisostomos, Pearl, Laurence H., Piper, Peter W.·2005·Eukaryotic Cell
Cited by (172)
Items 101–172 of 172
- A system based network approach to ethanol tolerance in Saccharomyces cerevisiaeCeyda Kasavi, Serpil Eraslan, Kazım Yalçın Arğa, Ebru Toksoy Öner, Betül Kırdar · 2014 · BMC Systems Biology
- A mitogen-activated protein kinase of Trypanosoma brucei confers resistance to temperature stress☆Andreas Guettinger, Claudia Schwab, Sabine Morand, Isabel J. Roditi, Erik Vassella · 2007 · Molecular and Biochemical Parasitology
- APEX2‐mediated proximity labeling resolves protein networks in Saccharomyces cerevisiae cellsBirgit Singer‐Krüger, Theresa Fröhlich, Mirita Franz‐Wachtel, Nicolas Nalpas, Boris Maček, Ralf‐Peter Jansen · 2019 · FEBS Journal
- She3p Possesses a Novel Activity Required for ASH1 mRNA Localization in Saccharomyces cerevisiaeSharon M. Landers, Michelle Gallas, Jaime L. Little, Roy M. Long · 2009 · Eukaryotic Cell
- Pharmacological targeting of host chaperones protects from pertussis toxin in vitro and in vivoKatharina Ernst, Ann‐Katrin Mittler, Veronika Eva Winkelmann, Carolin Kling, Nina Eberhardt, Anna Anastasia, Michael Sonnabend, Robin Lochbaum, Jan Wirsching, Moona Sakari et al. · 2021 · Scientific Reports
- Nucleotide exchange is sufficient for Hsp90 functions in vivoMichael J. Reidy, Kevin Garzillo, Daniel C. Masison · 2023 · Nature Communications
- UCS Proteins: Chaperones for Myosin and Co-Chaperones for Hsp90Weiming Ni, Odutayo O. Odunuga · 2014 · Sub-cellular biochemistry/Subcellular biochemistry
- Hsp90 chaperone control over transcriptional regulation by the yeast Slt2(Mpk1)p and human ERK5 mitogen-activated protein kinases (MAPKs)Peter W. Piper, Andrew W. Truman, Stefan H. Millson, James M. Nuttall · 2006 · Biochemical Society Transactions
- Evidence for Hsp90 Co-chaperones in Regulating Hsp90 Function and Promoting Client Protein FoldingMarc B. Cox, Jill L. Johnson · 2017 · Methods in molecular biology
- HSP90C interacts with PsbO1 and facilitates its thylakoid distribution from chloroplast stroma in ArabidopsisTim Jiang, Edward Saehong Oh, Diana Bonea, Rongmin Zhao · 2017 · PLoS ONE
- Geldanamycin selectively targets the nascent form of ERBB3 for degradationC. Sachi Gerbin, Ralf Landgraf · 2010 · Cell Stress and Chaperones
- The Nuclear and DNA-Associated Molecular Chaperone NetworkZlata Gvozdenov, Janhavi A. Kolhe, Brian Freeman · 2019 · Cold Spring Harbor Perspectives in Biology
- Establishing Order Through Disorder by the Hsp90 Molecular ChaperoneNeethu L. Babu, Brian Freeman · 2024 · Journal of Molecular Biology
- Hsp90 interaction networks in fungi—tools and techniquesJulia L. Crunden, Stephanie Diezmann · 2021 · FEMS Yeast Research
- Geldanamycin-Induced PCNA Degradation in Isolated Hsp90 Complex from Cancer CellsXing Wang, Deborah M. Heuvelman, James A. Carroll, Dawn R. Dufield, Jaime L. Masferrer · 2010 · Cancer Investigation
- An In Vivo Photo-Cross-Linking Approach Reveals a Homodimerization Domain of Aha1 in S. cerevisiaeMichael Berg, Annette Michalowski, Silke Palzer, Steffen Rupp, Kai Sohn · 2014 · PLoS ONE
- A general pipeline for quality and statistical assessment of protein interaction data using R and BioconductorTony Chiang, Denise Scholtens · 2009 · Nature Protocols
- ATP plays a structural role in Hsp90 functionMichael J. Reidy, Daniel C. Masison · 2025 · Nature Communications
- The evolution and diversification of the Hsp90 co-chaperone systemSonja Engler, Johannes Büchner · 2025 · Biological Chemistry
- Evidence for interaction between Hsp90 and the ER membrane complexTambudzai Kudze, Carlos Mendez‐Dorantes, Sallieu Jalloh, Amie Jo McClellan · 2018 · Cell Stress and Chaperones
- Cdc37p is involved in osmoadaptation and controls high osmolarity-induced cross-talk via the MAP kinase Kss1pXiao-Xian Yang, Patricija van Oosten‐Hawle, Jan Paul Bebelman, Annemarie Meenhuis, Marco H. Siderius, Saskia M. van der Vies · 2007 · FEMS Yeast Research
- Disrupting progression of the yeast Hsp90 folding pathway at different transition points results in client-specific maturation defectsKaitlyn Hohrman, Davi Ludvig Gonçalves, Kevin A. Morano, Jill L. Johnson · 2021 · Genetics
- Understanding chaperone specificity: evidence for a ‘client code’Siddhi Omkar, Ainella Rysbayeva, Andrew W. Truman · 2023 · Trends in Biochemical Sciences
- Mih1/Cdc25 is negatively regulated by Pkc1 in Saccharomyces cerevisiaeKouitiro Yano, Yukifumi Uesono, Satoshi Yoshida, Akihiko Kikuchi, Jun Kashiwazaki, Issei Mabuchi, Yoshiko Kikuchi · 2013 · Genes to Cells
- Nematode Sgt1-Homologue D1054.3 Binds Open and Closed Conformations of Hsp90 via Distinct Binding SitesJulia M. Eckl, Adrian Drazic, Daniel Andreas Rutz, Klaus Richter · 2014 · Biochemistry
- Hsp70-nucleotide exchange factor (NEF) Fes1 has non-NEF roles in degradation of gluconeogenic enzymes and cell wall integrityShailesh Kumar, Daniel C. Masison · 2019 · PLoS Genetics
- Selective functional inhibition of a tumor-derived p53 mutant by cytosolic chaperones identified using split-YFP in budding yeastAshley S. Denney, Andrew D. Weems, Michael A. McMurray · 2021 · G3 Genes Genomes Genetics
- Proteome‐wide search for PP2A substrates in fission yeastManuel Bernal, Jacob Zhurinsky, Ana Belén Iglesias-Romero, María Antonia Sánchez-Romero, Ignacio Flor‐Parra, Laura Tomás‐Gallardo, Antonio J. Pérez‐Pulido, Juan Jiménez, Rafael R. Daga · 2014 · PROTEOMICS
- Stress AdaptationAlistair J. P. Brown, Leah E. Cowen, Antonio Di Pietro, Janet Quinn · 2017 · ASM Press eBooks
- Regulation of Protein Transport Pathways by the Cytosolic Hsp90sAnna G. Mankovich, Brian Freeman · 2022 · Biomolecules
- Protozoan HSP90-Heterocomplex: Molecular Interaction Network and Biological SignificanceMaría J. Figueras, Pablo C. Echeverría, Sergio Oscar Angel · 2014 · Current Protein and Peptide Science
- Hsp90 and phosphorylation of the Slt2(Mpk1) MAP kinase activation loop are essential for catalytic, but not non-catalytic, Slt2-mediated transcription in yeastStefan H. Millson, Andrew W. Truman, Peter W. Piper · 2022 · Cell Stress and Chaperones
- The Hsp90/Cdc37p chaperone system is a determinant of molybdate resistance in Saccharomyces cerevisiaeStefan H. Millson, James M. Nuttall, Mehdi Mollapour, Peter W. Piper · 2009 · Yeast
- Insights into Hsp90 mechanism and in vivo functions learned from studies in the yeast, Saccharomyces cerevisiaeRios, Erick I., Hunsberger, Isabel L., Johnson, Jill L. · 2024 · Frontiers in Molecular Biosciences
- Heat Shock Protein 90 Regulates the Activity of Histone Deacetylase Sir2 in Plasmodium falciparumWahida Tabassum, Mrinnanda Bhattacharya, Sayan Bakshi, Mrinal Kanti Bhattacharyya · 2022 · mSphere
- Quantitative proteomic analysis reveals unique Hsp90 cycle-dependent client interactionsErick I. Rios, Davi Ludvig Gonçalves, Kevin A. Morano, Jill L. Johnson · 2024 · Genetics
- Saccharomyces cerevisiae as a tool for deciphering Hsp90 molecular chaperone functionSarah J. Backe, Mehdi Mollapour, Mark R. Woodford · 2023 · Essays in Biochemistry
- Hsp90 and metal‐binding J‐protein family chaperones are not critically involved in cellular iron–sulfur protein assembly and iron regulation in yeastFelipe A. Carvalho, Ulrich Mühlenhoff, Joseph J. Braymer, Vasilij Root, Martin Stümpfig, Carla Columbano Oliveira, Roland Lill · 2023 · FEBS Letters
- Promotion of Hyperthermic-Induced rDNA Hypercondensation in Saccharomyces cerevisiaeDonglai Shen, Robert V. Skibbens · 2020 · Genetics
- Mechanosensor-mediated Hsp70 phosphorylation orchestrates the landscape of the heat shock responseSiddhi Omkar, Jake T. Kline, James H. Grissom, Diyun Sun, Richard J. Chi, Jared A.M. Bard, Luca Fornelli, Andrew W. Truman · 2025 · Nature Communications
- Cdc37 engages in stable, S14A mutation-reinforced association with the most atypical member of the yeast kinome, Cdk-activating kinase (Cak1)Stefan H. Millson, Patricija van Oosten‐Hawle, Mohammed Alkuriji, Andrew W. Truman, Marco H. Siderius, Peter W. Piper · 2014 · Cell Stress and Chaperones
- UCS Chaperone Folding of the Myosin Head: A Function That Evolved before Animals and Fungi Diverged from a Common Ancestor More than a Billion Years AgoPeter W. Piper, Julia Elizabeth Scott, Stefan H. Millson · 2022 · Biomolecules
- Cloning and Expression Analysis of Heat Shock Protein Gene ZmHSP90-1 in MaizeLingling Liu, Sisi Liu, Jianfeng Weng, Chang-Tao Wang, Xinhai Li, Shihuang Zhang, Qinghua Shi, Lijuan Wang, Zhuanfang Hao · 2012 · ACTA AGRONOMICA SINICA
- Mutation of the Ser18 phosphorylation site on the sole Saccharomyces cerevisiae UCS protein, She4, can compromise high-temperature survivalSusana Gómez Escalante, Peter W. Piper, Stefan H. Millson · 2016 · Cell Stress and Chaperones
- Fungal Δ9-fatty acid desaturase: a unique enzyme at the core of lipid metabolism in Aspergillus fumigatus and a promising target for the search for antifungal strategiesJonatas Erick Maimoni Campanella, Leonardo Talachia Rosa, Iran Malavazi · 2025 · mBio
- UNC-45: A Chaperone for Myosin and a Co-Chaperone for Hsp90Odutayo O. Odunuga, Henry F. Epstein · 2007 · Springer eBooks
- Heat Shock ResponseNora S. Plesofsky · 2014 · ASM Press eBooks
- The Interaction Network of the Hsp90 Molecular ChaperoneKamran Rizzolo, Philip Wong, Elisabeth R.M. Tillier, Walid A. Houry · 2014 · Springer eBooks
- Comparative transcriptome analysis of yeast strains carryingslt2,rlm1,andpop2deletionsManuel Becerra, Luís Lombardía, Mónica Lamas Maceiras, Elena Canto, Esther M. Rodriguez-Belmonte, M. Esperanza Cerdán · 2011 · Genome
- A novel multifunctional role for Hsp70 in binding post-translational modifications on client proteinsNitika Nitika, Bo Zheng, Linhao Ruan, Jake T. Kline, Jacek W. Sikora, Mara Texeira Torres, Yuhao Wang, Jade E. Takakuwa, Romain Huguet, Cinzia Klemm et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- Genes involved in protein folding and chromatin organization buffer genetic variationJens Frickel, Mohammed Talib Tawfeeq, Emily Baker, Sara Baco, Jonas Rombout, Karin Voordeckers, Daniel F. Jarosz, Sibylle Chantal Vonesch, Kevin J. Verstrepen · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- Dissecting the Cdc37 cochaperone code: Functional roles in chaperone-mediated stress adaptationMegan M. Mitchem, Ashley Choi, Duhita A Mirikar, Rajlekha Deb, Andrew W. Truman · 2025 · Journal of Biological Chemistry
- Ydj1 interaction at nucleotide-binding-domain of yeast Ssa1 impacts Hsp90 collaboration and client maturationDeepika Gaur, Navinder Kumar, Abhirupa Ghosh, Prashant R. Singh, Pradeep Kumar, Jyoti Guleria, Satinderdeep Kaur, Nikhil Malik, Sudipto Saha, Thomas Nyström et al. · 2022 · PLoS Genetics
- Cytosolic Heat Shock Protein 90 in Plant Hormone and Environmental Stress ResponseKenji Yamada, Etsuko Watanabe · 2019 · Heat shock proteins
- Neuroprotective Features Of Hsp90 Inhibitors Exhibiting Anti-Inflammatory Actions: Implications For Multiple SclerosisDouglas L. Feinstein, Alessandra Spagnolo, Cinzia Dello Russo · 2008 · Springer eBooks
- Emergence and Characterization of the p23 Molecular ChaperoneFrank Echtenkamp, Brian Freeman · 2014 · Springer eBooks
- Beyond Chaperoning: UCS Proteins Emerge as Regulators of Myosin-Mediated Cellular ProcessesOdutayo O. Odunuga, Andrés F. Oberhauser · 2022 · Sub-cellular biochemistry/Subcellular biochemistry
- Study on Hsp90 Expression in Different Tissues and Its Antibody in Serum of Chickens Infected with Marek's DiseasesYubao Li, Juan LI, Zhiliang Wang, Sidang Liu · 2014 · Journal of Integrative Agriculture
- The Candida albicans Hsp90 Chaperone Network Is Environmentally Flexible and Evolutionarily DivergentStephanie Diezmann, Leah E. Cowen · 2014 · Springer eBooks
- Sti1/Hop Plays a Pivotal Role in Hsp90 Regulation Beyond Bridging Hsp70Michael J. Reidy · 2019 · Heat shock proteins
- The Role of Chloroplast Localized Molecular Chaperone HSP90 in Arabidopsis thaliana DevelopmentSaehong E. Oh · 2012 · TSpace (University of Toronto)
- Biochemical analysis of proteins in the telomere maintenance pathwayDiane C. DeZwaan · 2011 · Illinois Digital Environment for Access to Learning and Scholarship (University of Illinois at Urbana-Champaign)
- The Role of Molecular Chaperones in Yeast Cell Wall Integrity and Identification of Chaperone Modulators that Interfere with Simian Virus 40 ReplicationChristine M. Wright · 2007 · D-Scholarship@Pitt (University of Pittsburgh)
- Experimental Illumination of Comprehensive Fitness Landscapes: A DissertationRyan T. Hietpas · 2013 · eScholarship@UMassChan
- siderophore transporters (ARN) and glutathione: H + antiporters (GEX) have a common evolutionary origin in hemiascomycete yeastsPaulo Jorge Dias, Isabel Sá‐Correia · 2013
- The Roles of Hsp90 and Calcineurin in Antifungal Drug ResistanceSheena Singh · 2012 · TSpace (University of Toronto)
- Current awareness on yeast2005 · Yeast
- Faculty Opinions recommendation of Threonine 22 phosphorylation attenuates Hsp90 interaction with cochaperones and affects its chaperone activity.Norma Araceli Bobadilla, Jonatan Barrera‐Chimal · 2011 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
- Hsp90 co-chaperone FKBP4 facilitates CCT8 folding and connects Hsp90 to chaperonin-dependent proteostasisYun-Yu Huang, Ya-Lan Chang, Yun Chen, Wei-Yu Chiang, Ai-Tao Chiang, Pang‐Hung Hsu, Shu‐Chun Teng · 2025 · Journal of Biological Chemistry
- Comparative analysis of the impact of Heat shock protein 90 kDa or Cdc37 mutation on the yeast proteomeErick I. Rios, Jill L. Johnson · 2026 · Cell Stress and Chaperones
- Emw1/TTC27 is a chaperone required for folding of the eukaryotic elongation factor 2Mengqi Yang, Ruixin Li, Anna Mikolajczak, Vanessa A. Wright, Mahnoor Hassan, Cara K. Vaughan, Thomas A. K. Prescott, Jennifer A. Heritz, Mehdi Mollapour, Barry Panaretou · 2026 · Cellular and Molecular Life Sciences
- Hsp90-Mediated Maturation of Kinases and Nuclear Steroid Hormone Receptors: A DissertationNatalie W. Pursell · 2011