Characterization of the Specific Interaction between Sialoadhesin and Sialylated Campylobacter jejuni Lipooligosaccharides

Heikema, Astrid P.; Bergman, Mathijs P.; Richards, Hannah; Crocker, Paul R.; Gilbert, Michel; Samsom, Janneke N.; van Wamel, Willem J. B.; Endtz, Hubert P.; van Belkum, Alex

doi:10.1128/iai.01273-09

Characterization of the Specific Interaction between Sialoadhesin and Sialylated Campylobacter jejuni Lipooligosaccharides

In Campylobacter jejuni -induced Guillain-Barré syndrome (GBS), molecular mimicry between C. jejuni lipooligosaccharide (LOS) and host gangliosides leads to the production of cross-reactive antibodies directed against the peripheral nerves of the host. Currently, the presence of surface exposed …