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Primary sequence of the alpha-toxin gene from Staphylococcus aureus wood 46
Open accessAbstract
The complete DNA sequence of a cloned alpha-toxin gene from Staphylococcus aureus was determined. The amino acid sequence of the alpha-toxin protein, predicted from the DNA sequence, was described and compared with published data. The primary product of the cloned alpha-toxin gene contained a 26-amino-acid leader sequence which possessed characteristic features of a signal sequence involved in secretion. The mature alpha-toxin protein had a molecular size of 33,000 and contained only three short regions of high hydrophobicity in addition to a number of short, weakly hydrophobic regions.
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Cited by
Structure of Staphylococcal α-Hemolysin, a Heptameric Transmembrane Pore
Song, L., Hobaugh, M. R., Shustak, C., Cheley, S., Bayley, H., & Gouaux, J. E. (1996) · Science · doi:10.1126/science.274.5294.1859 · Cited by 2,377
Synthesis of staphylococcal virulence factors is controlled by a regulatory RNA molecule.
Novick, R. P., Ross, H. F., Projan, S. J., Kornblum, J., Kreiswirth, B., & Moghazeh, S. (1993) · The EMBO Journal · doi:10.1002/j.1460-2075.1993.tb06074.x · Cited by 1,072
Morfeldt, E., Taylor, D., von Gabain, A., & Arvidson, S. (1995) · The EMBO Journal · doi:10.1002/j.1460-2075.1995.tb00136.x · Cited by 476
Theagr P2 operon: An autocatalytic sensory transduction system inStaphylococcus aureus
Novick, R. P., Projan, S. J., Kornblum, J., Ross, H. F., Ji, G., Kreiswirth, B., Vandenesch, F., Moghazeh, S., & Novick, R. P. (1995) · Molecular and General Genetics MGG · doi:10.1007/bf02191645 · Cited by 461
Bhakdi, S., Bayley, H., Valeva, A., Walev, I., Walker, B., Weller, U., Kehoe, M., & Palmer, M. (1996) · Archives of Microbiology · doi:10.1007/s002030050300 · Cited by 288
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Metadata
- Authors
- Gray, G. S., & Kehoe, M.
- Venue
- Infection and Immunity
- Publisher
- American Society for Microbiology
- Published
- 1984-11
- Volume
- 46
- Issue
- 2
- Pages
- 615-618
- ISSN
- 0019-9567 (ISSN-L)
- 1098-5522
- OpenAlex
- W1892071490
- Cited by
- 167
- References
- 0
- FWCI
- 7.25
- Type
- journal article
- Language
- en
- Open access
- green
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- Gray, G. S., & Kehoe, M. (1984). Primary sequence of the alpha-toxin gene from Staphylococcus aureus wood 46. Infection and Immunity. https://doi.org/10.1128/iai.46.2.615-618.1984
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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