The DOI matches its Crossref record; 24 of the 24 references it cites were found in a registry or an index.
Nisin, a peptide antibiotic: cloning and sequencing of the nisA gene and posttranslational processing of its peptide product
Open accessAbstract
Nisin produced by Streptococcus lactis is used as a food preservative and is the most important member of a group of antibiotics containing lanthionine bridges. To understand the genetic basis of these so-called lantibiotics (Schnell et al., Nature 333:276-278, 1988), we characterized the nisin structural gene, nisA, which is located on a plasmid and codes for a 57-amino-acid prepeptide. The prepeptide is processed posttranslationally to the pentacyclic antibiotic. Although nisin and the recently elucidated lantibiotic epidermin from Staphylococcus epidermidis are produced by different organisms, their gene organization is identical. As with epidermin, the nisin propeptide corresponds to the C-terminus of the prepeptide. The N-terminus of the prepeptide is cleaved at a characteristic splice site (Pro--2 Arg--1 Ile-+1). Remarkably, the N-terminus of prenisin shares 70% similarity with preepidermin, although the propeptide sequences are distinctly different. The structural similarities between these two lantibiotics are consistent with the fact that there is a common mechanism of biosynthesis of these lanthionine-containing antibiotics.
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Cites
Detection of specific sequences among DNA fragments separated by gel electrophoresis
Southern, E. M. (1975) · Journal of Molecular Biology · doi:10.1016/s0022-2836(75)80083-0 · Cited by 32,249
Cloning in single-stranded bacteriophage as an aid to rapid DNA sequencing
Sanger, F., Coulson, A. R., Barrell, B. G., Smith, A. J. H., & Roe, B. A. (1980) · Journal of Molecular Biology · doi:10.1016/0022-2836(80)90196-5 · Cited by 3,407
Dideoxy sequencing method using denatured plasmid templates
Hattori, M., & Sakaki, Y. (1986) · Analytical Biochemistry · doi:10.1016/0003-2697(86)90403-3 · Cited by 1,444
Gross, E., & Morell, J. L. (1971) · Journal of the American Chemical Society · doi:10.1021/ja00747a073 · Cited by 605
Prepeptide sequence of epidermin, a ribosomally synthesized antibiotic with four sulphide-rings
Schnell, N., Entian, K.-D., Schneider, U., Götz, F., Zähner, H., Kellner, R., & Jung, G. (1988) · Nature · doi:10.1038/333276a0 · Cited by 538
Self-citationBuchman, G. W., Banerjee, S., & Hansen, J. N. (1988) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)37587-2 · Cited by 339
Gallidermin: a new lanthionine-containing polypeptide antibiotic
KELLNER, R., JUNG, G., HORNER, T., ZAHNER, H., SCHNELL, N., ENTIAN, K.-D., & GOTZ, F. (1988) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1988.tb14344.x · Cited by 313
Self-citationTHE INHIBITING EFFECT OF STREPTOCOCCUS LACTIS ON LACTOBACILLUS BULGARICUS
Rogers, L. A. (1928) · Journal of Bacteriology · doi:10.1128/jb.16.5.321-325.1928 · Cited by 269
FURTHER OBSERVATIONS ON AN INHIBITORY SUBSTANCE (NISIN) FROM LACTIC STREPTOCOCCI
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Epidermin: sequencing of a heterodet tetracyclic 21‐peptide amide antibiotic
ALLGAIER, H., JUNG, G., WERNER, R. G., SCHNEIDER, U., & ZÄHNER, H. (1986) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1986.tb09933.x · Cited by 251
Cited by
van der Meer, J. R., Polman, J., Beerthuyzen, M. M., Siezen, R. J., Kuipers, O. P., & De Vos, W. M. (1993) · Journal of Bacteriology · doi:10.1128/jb.175.9.2578-2588.1993 · Cited by 318
Piard, J. C., & Desmazeaud, M. (1992) · Le Lait · doi:10.1051/lait:199229 · Cited by 266
Cogan, T. M., & Hill, C. (1993) · Cheese: Chemistry, Physics and Microbiology · doi:10.1007/978-1-4615-2650-6_6 · Cited by 139
Antimicrobial Proteins: Classification, Nomenclature, Diversity, and Relationship to Bacteriocins
MONTVILLE, T. J., & KAISER, A. L. (1993) · Bacteriocins of Lactic Acid Bacteria · doi:10.1016/b978-0-12-355510-6.50009-9 · Cited by 44
Metadata
- Authors
- Kaletta, C., & Entian, K. D.
- Venue
- Journal of Bacteriology
- Publisher
- American Society for Microbiology
- Published
- 1989-03
- Volume
- 171
- Issue
- 3
- Pages
- 1597-1601
- ISSN
- 0021-9193 (ISSN-L)
- 1098-5530
- OpenAlex
- W1583265703
- Cited by
- 275
- References
- 24
- FWCI
- 22.03
- Type
- journal article
- Language
- en
- Open access
- green
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- Kaletta, C., & Entian, K. D. (1989). Nisin, a peptide antibiotic: cloning and sequencing of the nisA gene and posttranslational processing of its peptide product. Journal of Bacteriology. https://doi.org/10.1128/jb.171.3.1597-1601.1989
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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