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Cited by 379

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Guanine nucleotide-dependent assembly of FtsZ into filaments

Open access
Mukherjee, A, Lutkenhaus, J·1994·Journal of Bacteriology

Abstract

FtsZ is an essential cell division protein that is localized to the leading edge of the bacterial septum in a cytokinetic ring. It contains the tubulin signature motif and is a GTP binding protein with a GTPase activity. Further comparison of FtsZ with eukaryotic tubulins revealed some additional sequence similarities, perhaps indicating a similar GTP binding site. Examination of FtsZ incubated in vitro by electron microscopy revealed a guanine nucleotide-dependent assembly into protein filaments, supporting the hypothesis that the FtsZ ring is formed through self-assembly. FtsZ3, which is unable to bind GTP, does not polymerize, whereas FtsZ2, which binds GTP but is deficient in GTP hydrolysis, is capable of polymerization.

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Crossref · 10.1128/jb.176.9.2754-2758.1994

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Metadata

Authors
Mukherjee, A., & Lutkenhaus, J.
Venue
Journal of Bacteriology
Published
1994-05
Volume
176
Issue
9
Pages
2754-2758
ISSN
  • 0021-9193 (ISSN-L)
  • 1098-5530
OpenAlex
W2114750851
Cited by
379
References
1
FWCI
6.70
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Guanine nucleotide-dependent assembly of FtsZ into filaments. https://app.cochat.ai/papers/10.1128/jb.176.9.2754-2758.1994
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Mukherjee, A., & Lutkenhaus, J. (1994). Guanine nucleotide-dependent assembly of FtsZ into filaments. Journal of Bacteriology. https://doi.org/10.1128/jb.176.9.2754-2758.1994

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.