The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
CadC, the transcriptional regulatory protein of the cadmium resistance system of Staphylococcus aureus plasmid pI258
Open accessAbstract
The CadC protein from the cadA cadmium resistance operon of Staphylococcus aureus plasmid pI258 regulates transcription of this system in vitro. The CadC protein was overproduced in Escherichia coli cells and partially purified. Gel shift assays of the proposed cadA operator/promoter region DNA showed specific association with the CadC protein. Control arsenic resistance operator/promoter DNA from the same plasmid was not shifted by the CadC protein. Cd2+, Bi3+, and Pb2+ caused the release of CadC from DNA in gel retardation assays. DNase I footprinting measurements showed that the CadC protein specifically associated with and protected a region of operator/promoter DNA from nucleotide positions -7 to +14 relative to the start point of mRNA synthesis. Runoff transcription assays with the operator/promoter region of DNA (plus the first 69 nucleotides of the cadC gene) and purified E. coli RNA polymerase gave an mRNA product of the predicted size. Added CadC protein inhibited transcription in vitro.
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Nucifora, G., Chu, L., Misra, T. K., & Silver, S. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.10.3544 · Cited by 359 · cited 2×
“[10]), corresponding to positions 27 to 114 (Fig.”
BackgroundMethodSelf-citation
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Metadata
- Authors
- Endo, G., & Silver, S.
- Venue
- Journal of Bacteriology
- Publisher
- American Society for Microbiology
- Published
- 1995-08
- Volume
- 177
- Issue
- 15
- Pages
- 4437-4441
- ISSN
- 0021-9193 (ISSN-L)
- 1098-5530
- OpenAlex
- W2011557428
- Cited by
- 187
- References
- 1
- FWCI
- 4.66
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: CadC, the transcriptional regulatory protein of the cadmium resistance system of Staphylococcus aureus plasmid pI258. https://app.cochat.ai/papers/10.1128/jb.177.15.4437-4441.1995
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- Endo, G., & Silver, S. (1995). CadC, the transcriptional regulatory protein of the cadmium resistance system of Staphylococcus aureus plasmid pI258. Journal of Bacteriology. https://doi.org/10.1128/jb.177.15.4437-4441.1995
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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