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Cell Reproduction and Morphological Changes in Mycoplasma capricolum
Open accessAbstract
The cell reproduction of Mycoplasma capricolum was studied. The velocity of DNA replication fork progression was about 6 kb/min, which is 10 times slower than that of Escherichia coli . The time required for one round of DNA replication accorded with the doubling time. The origin/terminus ratio was 2.0. M. capricolum cell morphology was classified into two types, rod and branched. In the ordinary-growth phase, the rod cells accounted for about 90% of the total population, with branched cells comprising the remaining 10%. The proportion of branched cells increased to 90% following inhibition of DNA replication by nucleoside starvation. An increase in the proportion of branched cells was induced by transfer of a temperature-sensitive mutant deficient in DNA replication to the restrictive temperature. The rod cells had a regular structure, a fixed cell length, and constrictions in the center. The DNA contents of individual rod cells were distributed with a standard deviation of 0.40 of average. The branched cells had irregular structures and a wide distribution of DNA contents. Counting of viable cells revealed that the cells ceased division upon cell type conversion; however, branched cells maintained a reproductive capacity. A model for the reproduction process is proposed.
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“In phylogenetically related mycoplasmas in the M. mycoides group, only incomplete models of cell division have been reported”
From Genetic requirements for cell division in a genomically minimal cell (2020) · cites this paper as Seto and Miyata, 1998
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Cites
Molecular Cloning: A Laboratory Manual
Sambrook, J., Fritsch, E., & Maniatis, T. (1989) · UCLA - Biblioteca de Ciencias de la Salud · Cited by 133,589
Church, G. M., & Gilbert, W. (1984) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.81.7.1991 · Cited by 8,213
Cold Spring Harbor Laboratory; Cold Spring Harbor, NY
Cavalier-Smith, T. (1980) · FEBS Letters · doi:10.1016/0014-5793(80)80323-1 · Cited by 6,317
Transmission Electron Microscopy
Williams, D. B., & Carter, C. B. (2009) · Springer eBooks · doi:10.1007/978-0-387-76501-3 · Cited by 4,146
The Minimal Gene Complement of Mycoplasma genitalium
Fraser, C. M., Gocayne, J. D., White, O., Adams, M. D., Clayton, R. A., Fleischmann, R. D., Bult, C. J., Kerlavage, A. R., Sutton, G., Kelley, J. M., et al. (1995) · Science · doi:10.1126/science.270.5235.397 · Cited by 2,545
Complete Sequence Analysis of the Genome of the Bacterium Mycoplasma Pneumoniae
Himmelreich, R., Hilbert, H., Plagens, H., Pirkl, E., Li, B.-C., & Herrmann, R. (1996) · Nucleic Acids Research · doi:10.1093/nar/24.22.4420 · Cited by 1,142
A phylogenetic analysis of the mycoplasmas: basis for their classification
Weisburg, W. G., Tully, J. G., Rose, D. L., Petzel, J. P., Oyaizu, H., Yang, D., Mandelco, L., Sechrest, J. E., Lawrence, T. G., & Etten, J. L. V. (1989) · Journal of Bacteriology · doi:10.1128/jb.171.12.6455-6467.1989 · Cited by 746
Lilley, D. M. J. (1992) · Trends in Biochemical Sciences · doi:10.1016/0968-0004(92)90410-b · Cited by 576
(1983) · Elsevier eBooks · doi:10.1016/b978-0-12-583802-3.x5001-0 · Cited by 321
FtsZ ring formation in fts mutants
Addinall, S. G., Bi, E., & Lutkenhaus, J. (1996) · Journal of Bacteriology · doi:10.1128/jb.178.13.3877-3884.1996 · Cited by 298
Research works printed but not linked: 3
- Buxton A. Fraser G. Mycoplasma, Acholeplasma and L-form of bacteria Animal microbiology 1 1977 267 283 Blackwell Scientific Publications Ltd. Oxford, United Kingdom
- Helmstetter F. C. Timing of synthetic activities in the cell cycle Escherichia coli and Salmonella: cellular and molecular biology 2nd ed. Neidhardt F. C. Curtiss R. III Ingraham J. L. Lin E. C. C. Low K. B. Magasanik B. Reznikoff W. S. Riley M. Schaechter M. Umbarger H. E. 1996 1627 1639 ASM Press Washington D.C
- Rodwell W. A. Abbot A. Morphology of Mycoplasma mycoides.J. Gen. Microbiol.251961201214
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Molecular Biology and Pathogenicity of Mycoplasmas
Razin, S., Yogev, D., & Naot, Y. (1998) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.62.4.1094-1156.1998 · Cited by 1,930
Genome Transplantation in Bacteria: Changing One Species to Another
Lartigue, C., Glass, J. I., Alperovich, N., Pieper, R., Parmar, P. P., Hutchison, C. A., Smith, H. O., & Venter, J. C. (2007) · Science · doi:10.1126/science.1144622 · Cited by 497
The replication-related organization of bacterial genomes
Rocha, E. P. C. (2004) · Microbiology · doi:10.1099/mic.0.26974-0 · Cited by 279
Couturier, E., & Rocha, E. (2006) · Molecular Microbiology · doi:10.1111/j.1365-2958.2006.05046.x · Cited by 220
The origin of eukaryotes: the difference between prokaryotic and eukaryotic cells
Vellai, T., & Vida, G. (1999) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.1999.0817 · Cited by 180
Seto, S., Layh‐Schmitt, G., Kenri, T., & Miyata, M. (2001) · Journal of Bacteriology · doi:10.1128/jb.183.5.1621-1630.2001 · Cited by 140
Self-citationOrigin of replication in circular prokaryotic chromosomes
Worning, P., Jensen, L. J., Hallin, P. F., Stærfeldt, H., & Ussery, D. W. (2005) · Environmental Microbiology · doi:10.1111/j.1462-2920.2005.00917.x · Cited by 121
Miyata, M., Yamamoto, H., Shimizu, T., Uenoyama, A., Citti, C., & Rosengarten, R. (2000) · Microbiology · doi:10.1099/00221287-146-6-1311 · Cited by 86
Self-citationThe Genus Mycoplasma and Related Genera (Class Mollicutes)
Razin, S. (2006) · Springer eBooks · doi:10.1007/0-387-30744-3_29 · Cited by 81
Mycoplasma pneumoniae: a reduced-genome intracellular bacterial pathogen
Meseguer, M. A., ALVAREZ, A., Rejas, M. T., SANCHEZ, C., Pérez-Díaz, J. C., & Baquero, F. (2003) · Infection Genetics and Evolution · doi:10.1016/s1567-1348(02)00151-x · Cited by 67
Glew, M. D., Marenda, M. S., Rosengarten, R., & Citti, C. (2002) · Journal of Bacteriology · doi:10.1128/jb.184.21.5987-5998.2002 · Cited by 51
Use of Thymine Limitation and Thymine Starvation To Study Bacterial Physiology and Cytology
Zaritsky, A., Woldringh, C. L., Einav, M., & Alexeeva, S. (2006) · Journal of Bacteriology · doi:10.1128/jb.188.5.1667-1679.2006 · Cited by 47
Foley, P. L., & Shuler, M. L. (2009) · Biotechnology and Bioengineering · doi:10.1002/bit.22575 · Cited by 45
Clark, G. W., & Tillier, E. R. M. (2010) · Biochemistry and Cell Biology · doi:10.1139/o09-157 · Cited by 38
Cell reproduction cycle of mycoplasma
Miyata, M., & Seto, S. (1999) · Biochimie · doi:10.1016/s0300-9084(00)87171-0 · Cited by 33
Self-citationBringing the genetically minimal cell to life on a computer in 4D
Thornburg, Z. R., Maytin, A., Kwon, J., Brier, T. A., Gilbert, B. R., Fu, E., Gao, Y.-L., Quenneville, J., Wu, T., Li, H., et al. (2026) · Cell · doi:10.1016/j.cell.2026.02.009 · Cited by 44
Miyata, M., & Ogaki, H. (2006) · Microbial Physiology · doi:10.1159/000094059 · Cited by 32
Self-citationShuler, M. L., Foley, P., & Atlas, J. (2012) · Methods in molecular biology · doi:10.1007/978-1-61779-827-6_20 · Cited by 30
Browning, S. T., Castellanos, M., & Shuler, M. L. (2004) · Biotechnology and Bioengineering · doi:10.1002/bit.20223 · Cited by 26
Molecular Mechanism of Mycoplasma Gliding - A Novel Cell Motility System
Miyata, M. (2007) · Biological and medical physics series · doi:10.1007/978-0-387-73050-9_6 · Cited by 21
Self-citationPartitioning, Movement, and Positioning of Nucleoids in Mycoplasma capricolum
Seto, S., & Miyata, M. (1999) · Journal of Bacteriology · doi:10.1128/jb.181.19.6073-6080.1999 · Cited by 21
Self-citationEnvironmental stress speeds up DNA replication in Pseudomonas putida in chemostat cultivations
Lieder, S., Jahn, M., Koepff, J., Müller, S., & Takors, R. (2015) · Biotechnology Journal · doi:10.1002/biot.201500059 · Cited by 16
Integrative characterization of the near‐minimal bacterium Mesoplasma florum
Matteau, D., Lachance, J., Grenier, F., Gauthier, S., Daubenspeck, J. M., Dybvig, K., Garneau, D., Knight, T. F., Jacques, P., & Rodrigue, S. (2020) · Molecular Systems Biology · doi:10.15252/msb.20209844 · Cited by 16
“…subspecies capri exhibits a doubling time of ~ 60 min in rich medium (Gibson et al , 2010; Hutchison et al , 2016), while it is estimated to be around 90 min for M. capricolum subspecies capri-colum (Seto & Miyata, 1998) and 8 – 20 h for M. pneumoniae (Yus et al , 2009; Wodke et al , 2013).”
Genome economization and a new approach to the species concept in bacteria
Vellai, T., Kovacs, A. L., Kovács, G. M., Ortutay, C., & Vida, G. (1999) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.1999.0872 · Cited by 14
Miyata, M. (2002) · Springer eBooks · doi:10.1007/0-306-47606-1_6 · Cited by 9
Self-citationGenetic requirements for cell division in a genomically minimal cell
Pelletier, J. F., Sun, L., Wise, K. S., Assad-Garcia, N., Karas, B. J., Deerinck, T. J., Ellisman, M. H., Mershin, A., Gershenfeld, N., Chuang, R.-Y., et al. (2020) · bioRxiv / Cell · doi:10.1101/2020.10.07.326892 · Cited by 148
“In phylogenetically related mycoplasmas in the M. mycoides group, only incomplete models of cell division have been reported (Seto and Miyata, 1998).”
BackgroundDNA Replication, Repair and Stress Response
Zou, N., & Dybvig, K. F. (2002) · Springer eBooks · doi:10.1007/0-306-47606-1_13 · Cited by 8
Echtenkamp, P., Wilson, D. B., & Shuler, M. L. (2008) · Biotechnology and Bioengineering · doi:10.1002/bit.22098 · Cited by 4
Mesoplasma florum: a near-minimal model organism for systems and synthetic biology
Matteau, D., Duval, A., Baby, V., & Rodrigue, S. (2024) · Frontiers in Genetics · doi:10.3389/fgene.2024.1346707 · Cited by 2
Genome size and nucleotide skews as predictors of bacterial growth rate
Sahu, P., Barik, S., Ghosh, K., & Subramanian, H. (2026) · Physical Biology · doi:10.1088/1478-3975/ae5015 · Cited by 1
Estudio de la Expresión Génica y la División Celular en Mycoplasma genitalium
Lluch‐Senar, M. (2010) · Tesis Doctorals en Xarxa (Consorci de Serveis Universitaris de Catalunya)
Razin, S. (2010) · doi:10.1002/9780470688618.taw0077
[Molecular mechanism of Mycoplasma gliding; a unique biomotility].
Miyata, M. (2007) · Nippon Saikingaku Zasshi · doi:10.3412/jsb.62.347
Self-citationChromosome segregation in a minimal bacterial cell driven by SMC protein complexes
Maytin, A. K., Gilbert, B. R., & Luthey-Schulten, Z. (2026) · Protein Science · doi:10.1002/pro.70604
Metadata
- Authors
- Seto, S., & Miyata, M.
- Affiliations
- Osaka City University (JP)
- Venue
- Journal of Bacteriology
- Publisher
- American Society for Microbiology
- Published
- 1998-01-15
- Volume
- 180
- Issue
- 2
- Pages
- 256-264
- ISSN
- 0021-9193 (ISSN-L)
- 1098-5530
- PMC
- PMC106880
- OpenAlex
- W2139271927
- Cited by
- 35
- References
- 42
- Citations by year
- 2026: 3 · 2024: 1 · 2021: 1 · 2020: 1 · 2019: 1 · 2015: 1 · 2012: 1
- FWCI
- 1.90
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Locations
- Journal of Bacteriology (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Immunology and Microbiology › Microbiology › Microbial infections and disease research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Bacterial Genetics and Biotechnology
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Phytoplasmas and Hemiptera pathogens
- Keywords
- Mycoplasma capricolum, cell reproduction, cell morphology, rod photoreceptors, temperature-sensitive mutants, DNA content distribution, cell type conversion
- MeSH terms
- Bacterial Proteins, DNA Replication, DNA, Bacterial, Kinetics, Mycoplasma, Temperature
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