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Cited by 605

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

The Phage Proteomic Tree: a Genome-Based Taxonomy for Phage

Open access
Rohwer, Forest, Edwards, Rob·2002·Journal of Bacteriology

Abstract

There are ∼10 31 phage in the biosphere, making them the most abundant biological entities on the planet. Despite their great numbers and ubiquitous presence, very little is known about phage biodiversity, biogeography, or phylogeny. Information is limited, in part, because the current ICTV taxonomical system is based on culturing phage and measuring physical parameters of the free virion. No sequence-based taxonomic systems have previously been established for phage. We present here the “Phage Proteomic Tree,” which is based on the overall similarity of 105 completely sequenced phage genomes. The Phage Proteomic Tree places phage relative to both their near neighbors and all other phage included in the analysis. This method groups phage into taxa that predicts several aspects of phage biology and highlights genetic markers that can be used for monitoring phage biodiversity. We propose that the Phage Proteomic Tree be used as the basis of a genome-based taxonomical system for phage.

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Metadata

Authors
Rohwer, F., & Edwards, R.
Venue
Journal of Bacteriology
Published
2002-08-15
Volume
184
Issue
16
Pages
4529-4535
ISSN
  • 0021-9193 (ISSN-L)
  • 1098-5530
OpenAlex
W2154760096
Cited by
605
References
3
FWCI
19.13
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: The Phage Proteomic Tree: a Genome-Based Taxonomy for Phage. https://app.cochat.ai/papers/10.1128/jb.184.16.4529-4535.2002
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Rohwer, F., & Edwards, R. (2002). The Phage Proteomic Tree: a Genome-Based Taxonomy for Phage. Journal of Bacteriology. https://doi.org/10.1128/jb.184.16.4529-4535.2002

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