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Escherichia coli mazEF -Mediated Cell Death Is Triggered by Various Stressful Conditions
Open accessAbstract
mazEF is an Escherichia coli suicide module specific for a stable toxin and a labile antitoxin. Inhibiting mazEF expression appeared to activate the module to cause cell death. Here we show that several stressful conditions, including high temperatures, DNA damage, and oxidative stress, also induce mazEF -mediated cell death. We also show that this process takes place only during logarithmic growth and requires an intact relA gene.
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Vogelstein, B., Lane, D., & Levine, A. J. (2000) · Nature · doi:10.1038/35042675 · Cited by 6,607
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Eraso, J. M., Markillie, L. M., Mitchell, H. D., Taylor, R. C., Orr, G., & Margolin, W. (2014) · Journal of Bacteriology · doi:10.1128/jb.01370-13 · Cited by 87
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Metadata
- Authors
- Hazan, R., Sat, B., & Engelberg-Kulka, H.
- Venue
- Journal of Bacteriology
- Publisher
- American Society for Microbiology
- Published
- 2004-06
- Volume
- 186
- Issue
- 11
- Pages
- 3663-3669
- ISSN
- 0021-9193 (ISSN-L)
- 1098-5530
- OpenAlex
- W2156539285
- Cited by
- 254
- References
- 1
- FWCI
- 7.24
- Type
- journal article
- Language
- en
- Open access
- green
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- Hazan, R., Sat, B., & Engelberg-Kulka, H. (2004). Escherichia coli mazEF -Mediated Cell Death Is Triggered by Various Stressful Conditions. Journal of Bacteriology. https://doi.org/10.1128/jb.186.11.3663-3669.2004
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
