The DOI matches its Crossref record.
Peptide Nucleic Acid Fluorescence In Situ Hybridization-Based Identification of Candida albicans and Its Impact on Mortality and Antifungal Therapy Costs
Open accessAbstract
The impact of rapid identification of Candida albicans blood isolates by peptide nucleic acid fluorescence in situ hybridization (PNA FISH) on the selection and expenditure of antifungal therapy was evaluated. PNA FISH was 100% sensitive and specific in the rapid identification of 31 out of 72 candidemias as C. albicans and resulted in a significant reduction of caspofungin usage, with an overall cost savings of $1,729 per patient.
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Cited by
Banerjee, R., Teng, C. B., Cunningham, S. A., Ihde, S. M., Steckelberg, J. M., Moriarty, J. P., Shah, N. D., Mandrekar, J. N., & Patel, R. (2015) · Clinical Infectious Diseases · doi:10.1093/cid/civ447 · Cited by 570
Emerging Technologies for Molecular Diagnosis of Sepsis
Sinha, M., Jupe, J., Mack, H., Coleman, T. P., Lawrence, S. M., & Fraley, S. I. (2018) · Clinical Microbiology Reviews · doi:10.1128/cmr.00089-17 · Cited by 331
Emerging Technologies for the Clinical Microbiology Laboratory
Buchan, B. W., & Ledeboer, N. A. (2014) · Clinical Microbiology Reviews · doi:10.1128/cmr.00003-14 · Cited by 297
Metadata
- Authors
- Forrest, G. N., Mankes, K., Jabra-Rizk, M. A., Weekes, E., Johnson, J. K., Lincalis, D. P., & Venezia, R. A.
- Venue
- Journal of Clinical Microbiology
- Publisher
- American Society for Microbiology
- Published
- 2006-09
- Volume
- 44
- Issue
- 9
- Pages
- 3381-3383
- ISSN
- 0095-1137 (ISSN-L)
- 1098-660X
- OpenAlex
- W2142581361
- Cited by
- 174
- References
- 0
- FWCI
- 6.88
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: Peptide Nucleic Acid Fluorescence In Situ Hybridization-Based Identification of Candida albicans and Its Impact on Mortality and Antifungal Therapy Costs. https://app.cochat.ai/papers/10.1128/jcm.00751-06
- The paper
- Forrest, G. N., Mankes, K., Jabra-Rizk, M. A., Weekes, E., Johnson, J. K., Lincalis, D. P., & Venezia, R. A. (2006). Peptide Nucleic Acid Fluorescence In Situ Hybridization-Based Identification of Candida albicans and Its Impact on Mortality and Antifungal Therapy Costs. Journal of Clinical Microbiology. https://doi.org/10.1128/jcm.00751-06
Data sources
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.