Probiotic-Associated Aspiration Pneumonia Due to Lactobacillus rhamnosus
Open accessAbstract
Lactobacilli are low-virulence, commensal organisms of the gastrointestinal and genitourinary tracts and are commonly used as “probiotic supplements.” Herein, we describe an episode of respiratory syncytial virus (RSV) bronchiolitis with bacterial superinfection secondary to administration of Lactobacillus rhamnosus in an 11-month-old female with trisomy 21.
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Adverse events from probiotic strains in vulnerable populations include life-threatening pneumonia, endocarditis, and sepsis.
“AEs include life-threatening pneumonia,106 endocarditis,107–111 and sepsis.112–115”
From Emerging issues in probiotic safety: 2023 perspectives (2023) · cites this paper as [106]
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References 34 · Cited by 41
- Authors
- Doern, C. D., Nguyen, S. T., Afolabi, F., & Burnham, C.-A. D.
- Affiliations
- Virginia Commonwealth University (US)
- Children's Medical Center (US)
- The University of Texas Southwestern Medical Center (US)
- Washington University in St. Louis (US)
- Venue
- Journal of Clinical Microbiology
- Publisher
- American Society for Microbiology
- Published
- 2014-08
- Volume
- 52
- Issue
- 8
- Pages
- 3124-3126
- ISSN
- 0095-1137 (ISSN-L)
- 1098-660X
- PMC
- PMC4136183
- OpenAlex
- W2104310654
- Cited by
- 41
- References
- 34
- Citations by year
- 2026: 4 · 2025: 4 · 2024: 2 · 2023: 4 · 2022: 5 · 2021: 6 · 2020: 2 · 2019: 3 · 2018: 2 · 2017: 6 · 2016: 2 · 2014: 1
- FWCI
- 4.29
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Clinical Microbiology (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Digital Commons@Becker (Washington University School of Medicine) (submittedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
- Health Sciences › Medicine › Epidemiology › Respiratory viral infections research
- Health Sciences › Medicine › Epidemiology › Pneumonia and Respiratory Infections
- Keywords
- Lactobacillus rhamnosus, aspiration pneumonia, probiotics, secondary bacterial infection, respiratory syncytial virus bronchiolitis, Down syndrome, infants, commensal bacteria
- MeSH terms
- Bacterial Infections, Down Syndrome, Female, Humans, Infant, Pneumonia, Aspiration, Respiratory Syncytial Virus Infections, Probiotics, Lacticaseibacillus rhamnosus
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