CoChat
Sign Up
Cited by 16Malaria Research and ControlErythrocyte Function and PathophysiologyDrug Transport and Resistance Mechanisms

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

PMRT1, a Plasmodium -Specific Parasite Plasma Membrane Transporter, Is Essential for Asexual and Sexual Blood Stage Development

Open access
Wichers, Jan Stephan, Mesén-Ramírez, Paolo, Fuchs, Gwendolin, Yu-Strzelczyk, Jing, Stäcker, Jan, von Thien, Heidrun, Alder, Arne, Henshall, Isabelle, Liffner, Benjamin, Nagel, Georg, Löw, Christian, Wilson, Danny, Spielmann, Tobias, Gao, Shiqiang, Gilberger, Tim-Wolf, Bachmann, Anna, Strauss, Jan·2022·mBio
DOI 10.1128/mbio.00623-22PMC PMC9040750

Published version of a preprint

Open this paper in CoChat — free account

Abstract

Plasmodium falciparum -infected erythrocytes possess multiple compartments with designated membranes. Transporter proteins embedded in these membranes not only facilitate movement of nutrients, metabolites, and other molecules between these compartments, but also are common therapeutic targets and can confer antimalarial drug resistance.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1128/mbio.00623-22

Cites

3 of 3 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Flagged first, then by citations

Research works printed but not linked: 100

  1. 10.1186/gb-2005-6-3-r26 · DOI
  2. 10.1111/brv.12565 · DOI
  3. 10.1111/j.1365-2958.2009.06863.x · DOI
  4. 10.15698/mic2016.10.534 · DOI
  5. 10.1038/s41564-018-0222-7 · DOI
  6. 10.1038/362643a0 · DOI
  7. 10.1016/j.cell.2011.05.002 · DOI
  8. 10.3389/fpls.2014.00153 · DOI
  9. 10.1016/0092-8674(89)90330-9 · DOI
  10. 10.1016/S1097-2765(05)00077-8 · DOI
  11. 10.1038/ncomms11553 · DOI
  12. 10.1002/1873-3468.12079 · DOI
  13. 10.1016/j.chom.2021.11.002 · DOI
  14. 10.1073/pnas.91.3.1143 · DOI
  15. 10.1111/mmi.12505 · DOI
  16. 10.1038/nmicrobiol.2016.166 · DOI
  17. 10.1371/journal.ppat.1005725 · DOI
  18. 10.1126/science.aan4472 · DOI
  19. 10.1021/acsinfecdis.0c00676 · DOI
  20. 10.1016/j.actatropica.2003.10.002 · DOI
  21. 10.1016/j.pt.2010.05.002 · DOI
  22. 10.1016/j.chembiol.2021.06.006 · DOI
  23. 10.3389/fcell.2021.649184 · DOI
  24. 10.1074/jbc.273.17.10190 · DOI
  25. 10.1016/j.chom.2015.08.003 · DOI
  26. 10.1002/ddr.20347 · DOI
  27. 10.1016/j.mib.2021.07.010 · DOI
  28. 10.1016/j.mib.2021.07.016 · DOI
  29. 10.1371/journal.ppat.1009394 · DOI
  30. 10.1038/ncomms10519 · DOI
  31. 10.1111/cmi.12789 · DOI
  32. 10.1016/j.pt.2006.04.008 · DOI
  33. 10.1111/j.1365-2958.2009.07026.x · DOI
  34. 10.1128/mBio.01500-19 · DOI
  35. 10.1016/j.chom.2011.09.004 · DOI
  36. 10.1021/pr400394g · DOI
  37. 10.1093/nar/gkn814 · DOI
  38. 10.1002/pro.3749 · DOI
  39. 10.1038/nmeth.4223 · DOI
  40. 10.1371/journal.pone.0073783 · DOI
  41. 10.1128/EC.00124-10 · DOI
  42. 10.1016/j.chom.2018.11.010 · DOI
  43. 10.1093/emboj/19.8.1794 · DOI
  44. 10.1126/science.aax4735 · DOI
  45. 10.1016/j.jmb.2019.12.024 · DOI
  46. 10.1111/j.1600-0854.2012.01394.x · DOI
  47. 10.1128/mcb.9.7.3151-3154.1989 · DOI
  48. 10.1111/cmi.13341 · DOI
  49. 10.1371/journal.pone.0001355 · DOI
  50. 10.1038/nmeth.2301 · DOI
  51. 10.1038/317270a0 · DOI
  52. 10.1371/journal.pbio.3000473 · DOI
  53. 10.1186/1471-2164-12-587 · DOI
  54. 10.1093/nar/gkw536 · DOI
  55. 10.1038/s41467-021-24954-4 · DOI
  56. 10.1126/science.aan6042 · DOI
  57. Ennist NM Stayrook SE Dutton PL Moser CC. 2017. 5VJT: de novo photosynthetic reaction center protein equipped with heme B and Zn(II) cations. https://doi.org/10.2210/pdb5VJT/pdb. · DOI
  58. 10.2741/s344 · DOI
  59. 10.1074/jbc.M001478200 · DOI
  60. 10.1126/science.aap7847 · DOI
  61. 10.1371/journal.pbio.3000376 · DOI
  62. 10.1038/srep27531 · DOI
  63. 10.1371/journal.pbio.1001138 · DOI
  64. 10.1016/j.cell.2017.06.030 · DOI
  65. 10.1128/mSphere.00086-19 · DOI
  66. 10.1038/s41467-020-15479-3 · DOI
  67. Sonnhammer EL, von Heijne G, Krogh A. 1998. A hidden Markov model for predicting transmembrane helices in protein sequences. Proc Int Conf Intell Syst Mol Biol 6:175–182.
  68. 10.1016/j.jmb.2004.03.016 · DOI
  69. 10.1093/gbe/evw128 · DOI
  70. 10.1016/j.celrep.2018.02.075 · DOI
  71. 10.1038/srep40655 · DOI
  72. 10.1126/science.aaw2619 · DOI
  73. 10.1016/j.celrep.2020.107817 · DOI
  74. 10.12688/wellcomeopenres.9876.1 · DOI
  75. 10.1038/nature07306 · DOI
  76. 10.1016/s0020-7519(97)00080-5 · DOI
  77. 10.2307/3280287 · DOI
  78. 10.1017/S003118200005143X · DOI
  79. 10.1111/j.1550-7408.1983.tb02932.x · DOI
  80. 10.1073/pnas.1216457110 · DOI
  81. 10.1016/j.molbiopara.2011.01.004 · DOI
  82. 10.1016/B978-0-12-391856-7.00029-9 · DOI
  83. 10.1186/s12936-015-0784-2 · DOI
  84. 10.1371/journal.ppat.1003344 · DOI
  85. 10.1016/j.molbiopara.2004.05.009 · DOI
  86. 10.1016/0166-6851(91)90128-s · DOI
  87. 10.1038/nmeth.2019 · DOI · Paper page
  88. 10.1371/journal.ppat.1005618 · DOI
  89. 10.1242/jcs.02673 · DOI
  90. 10.1038/srep00118 · DOI
  91. 10.1128/mSphere.00743-21 · DOI
  92. 10.1098/rsos.171780 · DOI
  93. 10.1111/2041-210X.12628 · DOI
  94. 10.1002/cpbi.96 · DOI
  95. 10.1093/molbev/mst010 · DOI · Paper page
  96. 10.1093/nar/gkz268 · DOI · Paper page
  97. 10.3389/fbinf.2022.818619 · DOI
  98. 10.1083/jcb.202001064 · DOI · Paper page
  99. 10.1128/mSphere.01093-20 · DOI
  100. 10.1371/journal.ppat.1002964 · DOI

Metadata

Authors
Wichers, J. S., Mesén-Ramírez, P., Fuchs, G., Yu-Strzelczyk, J., Stäcker, J., von Thien, H., Alder, A., Henshall, I., Liffner, B., Nagel, G., Löw, C., Wilson, D., Spielmann, T., Gao, S., Gilberger, T.-W., Bachmann, A., & Strauss, J.
Affiliations
  • Centre for Structural Systems Biology, Hamburg, Germany
  • Bernhard Nocht Institute for Tropical Medicine (DE)
  • Universität Hamburg (DE)
  • University of Würzburg (DE)
  • Centre for Structural Systems Biology (DE)
  • The University of Adelaide (AU)
  • European Molecular Biology Laboratory (DE)
  • Burnet Institute (AU)
Corresponding author
  • Gilberger, Tim-Wolf
  • Strauss, Jan
ORCID
Venue
mBio
Publisher
American Society for Microbiology
Published
2022-04-26
Volume
13
Issue
2
Pages
e0062322-e0062322
ISSN
2150-7511 (ISSN-L)
DOI
10.1128/mbio.00623-22
PMC
PMC9040750
OpenAlex
W4226000753
Cited by
16
References
3
Citations by year
2026: 3 · 2025: 3 · 2024: 3 · 2023: 4 · 2022: 3
FWCI
2.87
Type
journal article
Language
en
Open access
Licence
Locations
  • mBio (publishedVersion, cc-by)
  • bioRxiv (Cold Spring Harbor Laboratory) (acceptedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • Desy publication database (The Deutsches Elektronen-Synchrotron) (publishedVersion, other-oa)
  • Helmholtz Centre for Ocean Research Kiel (GEOMAR) (acceptedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
  • DESY Publication Database (PUBDB) (Deutsches Elektronen-Synchrotron)
Funders
  • Deutsche Forschungsgemeinschaft (BA 5213/3-1, 374031971 TRR 240 A04, 417451587, SP1209/4-1)
  • Partnership of University of Hamburg and DESY (PIF-2018-87)
  • Centre for Structural Systems Biology (KIF 2019/002)
  • Hospital Research Foundation
  • Deutscher Akademischer Austauschdienst
  • Australian Government
  • Jürgen Manchot Stiftung
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Malaria Research and Control
  • Health Sciences › Medicine › Physiology (medical) › Erythrocyte Function and Pathophysiology
  • Health Sciences › Medicine › Oncology › Drug Transport and Resistance Mechanisms
Keywords
Plasmodium falciparum, asexual blood stage development, sexual development, subcellular localization, antimalarial drug resistance, therapeutic target, essential genes
MeSH terms
Animals, Cell Membrane, Humans, Parasites, Plasmodium, Plasmodium falciparum, Malaria, Falciparum, Membrane Transport Proteins

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review