The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Striking similarities are exhibited by two small Epstein-Barr virus-encoded ribonucleic acids and the adenovirus-associated ribonucleic acids VAI and VAII.
Open accessAbstract
The nucleotide sequence of the region of the Epstein-Barr virus genome that specifies two small ribonucleic acids (RNAs), EBER 1 and EBER 2, has been determined. Both of these RNAs are encoded by the right-hand 1,000 base pairs of the EcoRI J fragment of EBV deoxyribonucleic acid. EBER 1 is 166 (167) nucleotides long and EBER 2 is 172 +/- 1 nucleotides long; the heterogeneity resides at the 3' termini. The EBER genes are separated by 161 base pairs and are transcribed from the same deoxyribonucleic acid strand. In vitro, both EBER genes can be transcribed by RNA polymerase III; sequences homologous to previously identified RNA polymerase III intragenic transcription control regions are present. Striking similarities are therefore apparent both between the EBERs and the two adenovirus-associated RNAs, VAI and VAII, and between the regions of the two viral genomes that specify these small RNAs. We have shown that VAII RNA as well as VAI RNA and the EBERs exist in ribonucleoprotein complexes which are precipitable by anti-La antibodies associated with systemic lupus erythematosus. Finally, we have demonstrated that the binding of protein(s) from uninfected cells confers antigenicity on each of the four virus-encoded small RNAs.
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Cites
A rapid alkaline extraction procedure for screening recombinant plasmid DNA
Birnboim, H. C., & Doly, J. (1979) · Nucleic Acids Research · doi:10.1093/nar/7.6.1513 · Cited by 14,686
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Baer, R., Bankier, A. T., Biggin, M. D., Deininger, P. L., Farrell, P. J., Gibson, T. J., Hatfull, G., Hudson, G. S., Satchwell, S. C., Séguin, C., et al. (1984) · Nature · doi:10.1038/310207a0 · Cited by 2,053
Ablasser, A., Bauernfeind, F., Hartmann, G., Latz, E., Fitzgerald, K. A., & Hornung, V. (2009) · Nature Immunology · doi:10.1038/ni.1779 · Cited by 893
Topics in herpesvirus genomics and evolution
McGeoch, D. J., Rixon, F. J., & Davison, A. J. (2006) · Virus Research · doi:10.1016/j.virusres.2006.01.002 · Cited by 544
Hendrick, J. P., Wolin, S. L., Rinke, J., Lerner, M. R., & Steitz, J. A. (1981) · Molecular and Cellular Biology · doi:10.1128/mcb.1.12.1138 · Cited by 400
Self-citation5′-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I
Schmidt, A., Schwerd, T., Hamm, W., Hellmuth, J. C., Cui, S., Wenzel, M., Hoffmann, F. S., Michallet, M.-C., Besch, R., Hopfner, K.-P., et al. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0900971106 · Cited by 398
Metadata
- Authors
- Rosa, M. D., Gottlieb, E., Lerner, M. R., & Steitz, J. A.
- Venue
- Molecular and Cellular Biology
- Publisher
- Informa UK Limited
- Published
- 1981-09
- Volume
- 1
- Issue
- 9
- Pages
- 785-796
- ISSN
- 0270-7306 (ISSN-L)
- 1098-5549
- OpenAlex
- W1912540205
- Cited by
- 315
- References
- 1
- FWCI
- 10.95
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: Striking similarities are exhibited by two small Epstein-Barr virus-encoded ribonucleic acids and the adenovirus-associated ribonucleic acids VAI and VAII. https://app.cochat.ai/papers/10.1128/mcb.1.9.785
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- Rosa, M. D., Gottlieb, E., Lerner, M. R., & Steitz, J. A. (1981). Striking similarities are exhibited by two small Epstein-Barr virus-encoded ribonucleic acids and the adenovirus-associated ribonucleic acids VAI and VAII. Molecular and Cellular Biology. https://doi.org/10.1128/mcb.1.9.785
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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