The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Murine and human T-lymphocyte GATA-3 factors mediate transcription through a cis-regulatory element within the human T-cell receptor delta gene enhancer.
Open accessAbstract
A family of transcriptional activators has recently been identified in chickens; these transcriptional activators recognize a common consensus motif (WGATAR) through a conserved C4 zinc finger DNA-binding domain. One of the members of this multigene family, cGATA-3, is most abundantly expressed in the T-lymphocyte cell lineage. Analysis of human and murine GATA-3 factors shows a striking degree of amino acid sequence identity and similar patterns of tissue specificity of expression in these three organisms. The murine and human factors are abundantly expressed in a variety of human and murine T-cell lines and can activate transcription through a tissue-specific GATA-binding site identified within the human T-cell receptor delta gene enhancer. We infer that the murine and human GATA-3 proteins play a central and highly conserved role in vertebrate T-cell-specific transcriptional regulation.
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Cites
Transcriptional activation and DNA binding by the erythroid factor GF-1/NF-E1/Eryf 1.
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Self-citation
Cited by
A clonogenic common myeloid progenitor that gives rise to all myeloid lineages
Akashi, K., Traver, D., Miyamoto, T., & Weissman, I. L. (2000) · Nature · doi:10.1038/35004599 · Cited by 2,617
Zheng, W.-P., & Flavell, R. A. (1997) · Cell · doi:10.1016/s0092-8674(00)80240-8 · Cited by 2,384
Compilation of vertebrate-encoded transcription factors
Faisst, S., & Meyer, S. (1992) · Nucleic Acids Research · doi:10.1093/nar/20.1.3 · Cited by 914
GATA-binding transcription factors in hematopoietic cells
Orkin, S. (1992) · Blood · doi:10.1182/blood.v80.3.575.575 · Cited by 884
Zhang, D.-H., Cohn, L., Ray, P., Bottomly, K., & Ray, A. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.34.21597 · Cited by 665
Metadata
- Authors
- Ko, L. J., Yamamoto, M., Leonard, M. W., George, K. M., Ting, P., & Engel, J. D.
- Venue
- Molecular and Cellular Biology
- Publisher
- Informa UK Limited
- Published
- 1991-05
- Volume
- 11
- Issue
- 5
- Pages
- 2778-2784
- ISSN
- 0270-7306 (ISSN-L)
- 1098-5549
- OpenAlex
- W1946088674
- Cited by
- 293
- References
- 3
- FWCI
- 10.15
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: Murine and human T-lymphocyte GATA-3 factors mediate transcription through a cis-regulatory element within the human T-cell receptor delta gene enhancer. https://app.cochat.ai/papers/10.1128/mcb.11.5.2778
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- Ko, L. J., Yamamoto, M., Leonard, M. W., George, K. M., Ting, P., & Engel, J. D. (1991). Murine and human T-lymphocyte GATA-3 factors mediate transcription through a cis-regulatory element within the human T-cell receptor delta gene enhancer. Molecular and Cellular Biology. https://doi.org/10.1128/mcb.11.5.2778
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