Human Rad50 Is Physically Associated with Human Mre11: Identification of a Conserved Multiprotein Complex Implicated in Recombinational DNA Repair

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Items 101–200 of 224

1. Molecular disruption of RAD50 sensitizes human tumor cells to cisplatin-based chemotherapy
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2. The Drosophila melanogaster RAD54 Homolog, DmRAD54, Is Involved in the Repair of Radiation Damage and Recombination
   Rolf A. Kooistra, Kees Vreeken, José B.M. Zonneveld, Anja W. M. de Jong, Jan C. J. Eeken, Christopher J. Osgood, Jean-Marie Buerstedde, Paul H.M. Lohman, Albert Pastink · 1997 · Molecular and Cellular Biology
3. Telomeres and chromosomal instability
   Noëlle Mathieu, Livia Maria Pirzio, Marie-Anne Freulet-Marrière, Chantal Desmaze, Laure Sabatier · 2004 · Cellular and Molecular Life Sciences
4. RINT-1, a Novel Rad50-interacting Protein, Participates in Radiation-induced G2/M Checkpoint Control
   Jun Xiao, Chang-Ching Liu, Phang‐Lang Chen, Wen‐Hwa Lee · 2001 · Journal of Biological Chemistry
5. Intracellular redistribution and modification of proteins of the Mre11/Rad50/Nbs1 DNA repair complex following irradiation and heat‐shock
   Joshua D. Seno, Joseph R. Dynlacht · 2004 · Journal of Cellular Physiology
6. The plant Rad50–Mre11 protein complex
   Sylviane Cotterell, Maria Eugenia Gallego, Charles I. White · 2002 · FEBS Letters
7. Disruption of the Arabidopsis RAD50 gene leads to plant sterility and MMS sensitivity
   Maria Eugenia Gallego, Mélanie Jeanneau, Fabienne Granier, David Bouchez, Nichole Bechtold, Charles, Charles I. White · 2001 · The Plant Journal
8. Differential regulation of expression of the mammalian DNA repair genes by growth stimulation
   Ritsuko Iwanaga, Hideyuki Komori, Kiyoshi Ohtani · 2004 · Oncogene
9. Association of p53 and MSH2 with recombinative repair complexes during S phase
   Daniele Zink, Christoph Mayr, Christine Janz, Lisa Wiesmüller · 2002 · Oncogene
10. The Hermansky-Pudlak syndrome (HPS) protein is part of a high molecular weight complex involved in biogenesis of early melanosomes
    Jangsuk Oh · 2000 · Human Molecular Genetics
11. Formation of the yeast Mre11-Rad50-Xrs2 complex is correlated with DNA repair and telomere maintenance
    Mahmood Chamankhah, Wei Xiao · 1999 · Nucleic Acids Research
12. Repair of Endonuclease-Induced Double-Strand Breaks in Saccharomyces cerevisiae: Essential Role for Genes Associated with Nonhomologous End-Joining
    L. Kevin Lewis, James W. Westmoreland, Michael A. Resnick · 1999 · Genetics
13. Identification of defective illegitimate recombinational repair of oxidatively-induced DNA double-strand breaks in ataxia-telangiectasia cells
    Mubasher E. Dar, Thomas A. Winters, Timothy J. Jorgensen · 1997 · Mutation Research/DNA Repair
14. Localisation of RAD50 and MRE11 in spermatocyte nuclei of mouse and rat
    Maureen Eijpe, Hildo H. Offenberg, Wolfgang Goedecke, Christa Heyting · 2000 · Chromosoma
15. Translocation of MRE11 from the Nucleus to the Cytoplasm as a Mechanism of Radiosensitization by Heat1
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16. Genetic analysis of homologous DNA recombination in vertebrate somatic cells
    Ciaran G. Morrison, Shunichi Takeda · 2000 · The International Journal of Biochemistry & Cell Biology
17. The role of NBS1 in the modulation of PIKK family proteins ATM and ATR in the cellular response to DNA damage
    Junqing Zhou, Chang U.K. Lim, Jian Jian Li, Lu Cai, Ying Zhang · 2006 · Cancer Letters
18. DNA recombination and repair in the Archaea
    Erica M. Seitz, Cynthia A. Haseltine, Stephen C. Kowalczykowski · 2001 · Advances in applied microbiology
19. Disruption of Drosophila Rad50 causes pupal lethality, the accumulation of DNA double-strand breaks and the induction of apoptosis in third instar larvae
    Marcin M. Gorski, Ron J Romeijn, Jan C. J. Eeken, Anja W. M. de Jong, Bert L van Veen, Károly Szuhai, Leon H.F. Mullenders, Wouter Ferro, Albert Pastink · 2004 · DNA repair
20. Repair of ionizing radiation damage in mammalian cells. Alternative pathways and their fidelity
    John Thacker · 1999 · Comptes Rendus de l Académie des Sciences - Series III - Sciences de la Vie
21. Yeast Mutants As a Model System for Identification of Determinants of Chemosensitivity
    Paola Perego, Gretchen S. Jimenez, Laura Gatti, Stephen B. Howell, Franco Zunino · 2000 · Pharmacological Reviews
22. Bisbenzamidine derivative, pentamidine represses DNA damage response through inhibition of histone H2A acetylation
    Junya Kobayashi, Akihiro Kato, Yosuke Ota, Reiko Ohba, Kenshi Komatsu · 2010 · Molecular Cancer
23. Intrinsic and extrinsic mechanisms of oocyte loss
    Travis Thomson, Kathryn E. Fitzpatrick, Joshua Johnson · 2010 · Molecular Human Reproduction
24. Protecting genomic integrity during DNA replication: correlation between Werner's and Bloom's syndrome gene products and the MRE11 complex
    Annapaola Franchitto · 2002 · Human Molecular Genetics
25. Radiosensitization of heat resistant human tumour cells by 1 hour at 41.1°C and its effect on DNA repair
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26. Budding yeast Rad50, Mre11, Xrs2, and Hdf1, but not Rad52, are involved in the formation of deletions on a dicentric plasmid
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27. Comparison of Repair of DNA Double-Strand Breaks in Identical Sequences in Primary Human Fibroblast and Immortal Hamster–Human Hybrid Cells Harboring a Single Copy of Human Chromosome 11
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28. Triomics Analysis of Imatinib-Treated Myeloma Cells Connects Kinase Inhibition to RNA Processing and Decreased Lipid Biosynthesis
    Susanne B. Breitkopf, Min Yuan, Katja Helenius, Costas Andreas Lyssiotis, John M. Asara · 2015 · Analytical Chemistry
29. A New Connection at Human Telomeres: Association of the Mre11 Complex with TRF2
    Titia de Lange, John H.J. Petrini · 2000 · Cold Spring Harbor Symposia on Quantitative Biology
30. Formation of Linear Amplicons with Inverted Duplications in Leishmania Requires the MRE11 Nuclease
    Marie-Claude N. Laffitte, Marie‐Michelle Genois, Angana Mukherjee, Danielle Légaré, Jean‐Yves Masson, Marc Ouellette · 2014 · PLoS Genetics
31. Suppressor Analysis of the Saccharomyces cerevisiae Gene REC104 Reveals a Genetic Interaction With REC102
    Laura A. Salem, Natalie Walter, Robert Malone · 1999 · Genetics
32. Overexpressed human RAD50 exhibits cell death in a p21(WAF1/CIP1)-dependent manner: its potential utility in local gene therapy of tumor.
    Boo Ahn Shin, Kyu Youn Ahn, Hyun Kook, Jeong Tae Koh, In Cheol Kang, Hyun Chul Lee, Kyung Keun Kim · 2001 · PubMed
33. Nbs1-dependent binding of Mre11 to adenovirus E4 mutant viral DNA is important for inhibiting DNA replication
    Shomita S. Mathew‐Steiner, Eileen Bridge · 2008 · Virology
34. Genetic and molecular characterization of Neurospora crassamus-23 :a gene involved in recombinational repair
    K. Watanabe, Yoshiyuki Sakuraba, H. Inoue · 1997 · Molecular and General Genetics MGG
35. Intergenic Transcription Occurs throughout the Human IL-4/IL-13 Gene Cluster
    David F. Rogan, David J. Cousins, Dontcho Z. Staynov · 1999 · Biochemical and Biophysical Research Communications
36. Mutant Nbs1 Enhances Cisplatin‐Induced DNA Damage and Cytotoxicity in Head and Neck Cancer
    Hao Mimi Tran, Guoli Shi, Gouyan Li, James P. Carney, Bert O'Malley, Daqing Li · 2004 · Otolaryngology
37. The MRE11-NBS1-RAD50 pathway is perturbed in SV40 large T antigen-immortalized AT-1, AT-2 and HL-1 cardiomyocytes
    Nicholas A. Lanson · 2000 · Nucleic Acids Research
38. 1 Recombination in the Mammalian Germ Line
    D PITTMAN, John C. Schimenti · 1997 · Current topics in developmental biology/Current Topics in Developmental Biology
39. Mammalian X-ray-sensitive mutants which are defective in non-homologous (illegitimate) DNA double-strand break repair
    Małgorzata Z. Zdzienicka · 1999 · Biochimie
40. Panel of SEREX-defined antigens for breast cancer autoantibodies profile detection
    Olga Kostianets, Maksym Shyyan, С. В. Антонюк, Valeriy V Filonenko, Киямова Рамзия Галлямовна · 2016 · Biomarkers
41. Coprinus cinereus rad50Mutants Reveal an Essential Structural Role for Rad50 in Axial Element and Synaptonemal Complex Formation, Homolog Pairing and Meiotic Recombination
    Sonia N. Acharya, Alexander M. Many, Andrew P Schroeder, Felicia M. Kennedy, Oleksandr P. Savytskyy, Jennifer Grubb, Jack A Vincent, Elizabeth A Friedle, Martina Celerin, Daniel S. Maillet et al. · 2008 · Genetics
42. Gene targeted DNA double-strand break induction by 125l-labeled triplex-forming oligonucleotides is highly mutagenic following repair in human cells
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43. 4 Functions of DNA Repair Genes during Meiosis
    W. Jason Cummings, Miriam E. Zolan · 1997 · Current topics in developmental biology/Current Topics in Developmental Biology
44. Overexpression of kin17 protein forms intranuclear foci in mammalian cells
    Patricia L Kannouche, Ghislaine Pinon‐Lataillade, Ph. Mauffrey, C. Faucher, Denis S.F. Biard, Jaime F. Angulo · 1997 · Biochimie
45. Schizosaccharomyces pombe Rad32 protein: a phosphoprotein with an essential phosphoesterase motif required for repair of DNA double strand breaks
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46. Nitric oxide‐dependent cytoskeletal changes and inhibition of endothelial cell migration contribute to the suppression of angiogenesis by RAD50 gene transfer
    Hyun Kook, Kyu Youn Ahn, Song Eun Lee, Hee Sam Na, Kyung Keun Kim · 2003 · FEBS Letters
47. Effects of heat shock on the Mre11/Rad50/Nbs1 complex in irradiated or unirradiated cells
    Joseph R. Dynlacht, M. Xu, RAJ KUMAR PANDITA, Elizabeth A. Wetzel, Joseph L. Roti Roti · 2004 · International Journal of Hyperthermia
48. Hyperthermia alters the interaction of proteins of the Mre11 complex in irradiated cells
    Bogdan I. Gerashchenko, Gerirose Gooding, Joseph R. Dynlacht · 2010 · Cytometry Part A
49. Cancer-associated genes can affect somatic intrachromosomal recombination early in carcinogenesis
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50. Immunohistochemical analysis of medullary breast carcinoma autoantigens in different histological types of breast carcinomas
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51. Cloning and characterization of the Kluyveromyces lactis homologs of the Saccharomyces cerevisiae RED1 and HOP1 genes
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52. Isolation of hMRE11B: failure to complement yeast mre11 defects due to species-specific protein interactions
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53. Polypeptide Components of Telomere Nucleoprotein Complex
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54. A novel SMC-like protein, SbcE (YhaN), is involved in DNA double-strand break repair and competence in Bacillus subtilis
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55. End resection: a key step in homologous recombination and DNA double-strand break repair
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56. The Rad50 genes of diploid and polyploid wheat species. Analysis of homologue and homoeologue expression and interactions with Mre11
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57. Structural basis for DNA break sensing by human MRE11-RAD50-NBS1 and its regulation by telomeric factor TRF2
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58. Personalised Medicine: Genome Maintenance Lessons Learned from Studies in Yeast as a Model Organism
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59. A tool for enhancement and scoring of DNA repair foci
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60. Antibody-array technique reveals overexpression of important DNA-repair proteins during cardiac ischemic preconditioning
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61. Protective role of RAD50 on chromatin bridges during abnormal cytokinesis
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62. MR (Mre11-Rad50) complex in Giardia duodenalis: In vitro characterization and its response upon DNA damage
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63. Double-Strand Break Repair and Homologous Recombination in Mammalian Cells
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64. TOWARD MAINTAINING THE GENOME
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65. Disordered regions mediate the interaction of p53 and MRE11
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66. Serological Analysis of SEREX-Defined Medullary Breast Carcinoma-Associated Antigens
    Olga Kostianets, Maksym Shyian, Sergiy V. Demydov, Stepan Antoniuk, Ivan T. Gout, Valeriy V Filonenko, Киямова Рамзия Галлямовна · 2012 · Cancer Investigation
67. Pharmacological methods to transcriptionally modulate double-strand break DNA repair
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68. Genetics of Coprinus
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69. What Comparative Genomics Tells Us About the Evolution of Eukaryotic Genes Involved in Recombination
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70. Strategies for Cloning Mammalian DNA Repair Genes
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71. Simultaneous deregulation of p16 and cyclin D1 genes in pancreatic ductal adenocarcinoma: a combined immunohistochemistry and image analysis study based on tissue microarrays.
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72. Protein kinase CK2 interacts with Chk2 and phosphorylates Mre11 on serine 649
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73. Molecular cloning and characterization of splice variants of human RAD50 gene
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74. Structure and expression ofOsMRE11 in rice
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75. Extraordinary variation in radiation tolerance: Mechanisms and evolution
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76. The Pathways of Double-Strand Break Repair
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77. High expression of the circadian gene mPer2 diminishes the radiosensitivity of NIH 3T3 cells
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78. Effects of Chemical-Induced DNA Damage on Male Germ Cells
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80. The MRE11-RAD50 Complex
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81. Defective Signal Joint Recombination in Fanconi Anemia Fibroblasts Reveals a Role for Rad50 in V(D)J Recombination
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82. ATM , ATR and Mre11 complex genes in hereditary susceptibility to breast cancer
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83. DNA double-strand breaks induce formation of RP-A/Ku foci on in vitro reconstitutedXenopussperm nuclei
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84. Meiotic localization of Mre11 and Rad50 in wild type, spo11-1, and MRN complex mutants of Coprinus cinereus
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85. In Silico-Based Structural Evaluation to Categorize the Pathogenicity of Mutations Identified in the RAD Class of Proteins
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86. An Experimental Study on Autoignition of Wood
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87. Nijmegen Breakage Syndrome
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88. Nick-Directed Repair of Palindromic Loop Mismatches in Human Cell Extracts
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89. DNA End-Processing and Heteroduplex DNA Formation During Recombinational Repair of DNA Double-Strand Breaks
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90. New insights into the molecular basis of gametogenesis in the hybridogenetic water frog Pelophylax esculentus
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91. Chromosomeninstabilitätssyndrome
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92. Germline pathogenic variants associated with ovarian cancer: A historical overview
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93. Cellular Responses to Chemical Carcinogens
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94. The Role of Multimerization During Non-Homologous End Joining
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95. Telomeres, DNA Repair Proteins, and Making Ends Meet
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96. Structural basis for DNA double-strand break sensing by human MRE11-RAD50-NBS1 and its TRF2 complex
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97. Molecular processes and radiosensitivity
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98. WDFY2 promotes MRN complex formation required for homologous recombination-mediated DNA repair
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99. Strategies for Cloning Mammalian DNA Repair Genes
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100. Conservation of Eukaryotic DNA Repair Mechanisms
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