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Cited by 355

The DOI matches its Crossref record; 150 of the 150 references it cites were found in a registry or an index.

Protein trans -Acting Factors Involved in Ribosome Biogenesis in Saccharomyces cerevisiae

Open access
Kressler, Dieter, Linder, Patrick, de la Cruz, Jesús·1999·Molecular and Cellular Biology

Abstract

The synthesis of ribosomes is one of the major cellular activities, and in eukaryotes, it takes place primarily, although not exclusively, in a specialized subnuclear compartment termed the nucleolus (125, 155). There, the rRNA genes are transcribed as precursors (pre-rRNAs), which undergo processing and covalent modification. Maturation of pre-rRNAs is intimately linked to their assembly with the ribosomal proteins (r-proteins). These processes depend on various cis-acting elements (6, 188), and they require a large number of nonribosomal protein trans-acting factors (97, 174, 193). Experimental evidence suggests that the basic outline of ribosome synthesis is conserved throughout eukaryotes. However, most of our knowledge comes from the combination of molecular genetic and biochemical approaches in the yeast Saccharomyces cerevisiae. This minireview is aimed at giving an insight into the functions of the many protein trans-acting factors involved in ribosome biogenesis in S. cerevisiae.

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Metadata

Authors
Kressler, D., Linder, P., & de la Cruz, J.
Venue
Molecular and Cellular Biology
Published
1999-12
Volume
19
Issue
12
Pages
7897-7912
ISSN
  • 0270-7306 (ISSN-L)
  • 1098-5549
OpenAlex
W2165093821
Cited by
355
References
150
FWCI
10.22
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Protein trans -Acting Factors Involved in Ribosome Biogenesis in Saccharomyces cerevisiae. https://app.cochat.ai/papers/10.1128/mcb.19.12.7897
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Kressler, D., Linder, P., & de la Cruz, J. (1999). Protein trans -Acting Factors Involved in Ribosome Biogenesis in Saccharomyces cerevisiae. Molecular and Cellular Biology. https://doi.org/10.1128/mcb.19.12.7897

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.