The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Expression of the erythropoietin gene.
Open accessAbstract
Injection of cobalt into rats resulted in erythropoietin (EPO) mRNA accumulation in the kidney. The same response was obtained upon bleeding. No EPO mRNA was detected in the spleen, salivary gland, or thymus following cobalt injection or bleeding. In some animals, but not in others, EPO mRNA was also expressed in the liver in response to cobalt injection. Time course studies showed that message appearance begins sometime between 3 and 6 h after cobalt injection. This correlated very well with the EPO concentration in the circulation; EPO levels in the circulation were the same as those of controls at 3 h but increased to six- to sevenfold that of controls by 6 h after cobalt injection. The mature EPO mRNA in the rat and mouse comigrated with the 18S rRNA, indicating that it is about 1,850 nucleotides in length.
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Citations
Cites
Role of the kidney in erythropoiesis
JACOBSON, L. O., GOLDWASSER, E., FRIED, W., & PLZAK, L. (1957) · Nature · doi:10.1038/179633a0 · Cited by 862
Self-citation
Cited by
Semenza, G. L., & Wang, G. L. (1992) · Molecular and Cellular Biology · doi:10.1128/mcb.12.12.5447 · Cited by 2,617
Purification and Characterization of Hypoxia-inducible Factor 1
Wang, G. L., & Semenza, G. L. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.3.1230 · Cited by 2,073
Oxidative stress and gene regulation
Allen, R. G., & Tresini, M. (2000) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(99)00242-7 · Cited by 1,302
Semenza, G. L., Nejfelt, M. K., Chi, S. M., & Antonarakis, S. E. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.13.5680 · Cited by 990
Prabhakar, N. R., & Semenza, G. L. (2012) · Physiological Reviews · doi:10.1152/physrev.00030.2011 · Cited by 641
Metadata
- Authors
- Beru, N., McDonald, J., Lacombe, C., & Goldwasser, E.
- Venue
- Molecular and Cellular Biology
- Publisher
- Informa UK Limited
- Published
- 1986-07
- Volume
- 6
- Issue
- 7
- Pages
- 2571-2575
- ISSN
- 0270-7306 (ISSN-L)
- 1098-5549
- OpenAlex
- W2169155688
- Cited by
- 195
- References
- 1
- FWCI
- 7.37
- Type
- journal article
- Language
- en
- Open access
- green
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- Beru, N., McDonald, J., Lacombe, C., & Goldwasser, E. (1986). Expression of the erythropoietin gene. Molecular and Cellular Biology. https://doi.org/10.1128/mcb.6.7.2571
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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