The DOI matches its Crossref record; 71 of the 71 references it cites were found in a registry or an index.
Glucocorticoid Receptor Binding to a Specific DNA Sequence Is Required for Hormone-Dependent Repression of Pro-Opiomelanocortin Gene Transcription
Open accessAbstract
Glucocorticoids rapidly and specifically inhibit transcription of the pro-opiomelanocortin (POMC) gene in the anterior pituitary, thus offering a model for studying negative control of transcription in mammals. We have defined an element within the rat POMC gene 5'-flanking region that is required for glucocorticoid inhibition of POMC gene transcription in POMC-expressing pituitary tumor cells (AtT-20). This element contains an in vitro binding site for purified glucocorticoid receptor. Site-directed mutagenesis revealed that binding of the receptor to this site located at position base pair -63 is essential for glucocorticoid repression of transcription. Although related to the well-defined glucocorticoid response element (GRE) found in glucocorticoid-inducible genes, the DNA sequence of the POMC negative glucocorticoid response element (nGRE) differs significantly from the GRE consensus; this sequence divergence may result in different receptor-DNA interactions and may account at least in part for the opposite transcriptional properties of these elements. Hormone-dependent repression of POMC gene transcription may be due to binding of the receptor over a positive regulatory element of the promoter. Thus, repression may result from mutually exclusive binding of two DNA-binding proteins to overlapping DNA sequences.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Inhibition of CRH and ACTH induced by exogenous glucocorticoids is similar to the mechanisms involved in the physiologic cortisol negative feedback (16).”
From European Society of Endocrinology and Endocrine Society Joint Clinical Guideline: Diagnosis and Therapy of Glucocorticoid-induced Adrenal Insufficiency (2024) · cites this paper as [16]
Citations
Cites
Molecular Cloning: A Laboratory Manual
Sambrook, J., Fritsch, E., & Maniatis, T. (1989) · UCLA - Biblioteca de Ciencias de la Salud · Cited by 133,589
Molecular Cloning. A Laboratory Manual
Wood, E. (1983) · Biochemical Education · doi:10.1016/0307-4412(83)90068-7 · Cited by 29,534
Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease
Chirgwin, J. M., Przybyla, A., MacDonald, R. J., & Rutter, W. J. (1979) · Biochemistry · doi:10.1021/bi00591a005 · Cited by 21,460
Melton, D. A., Krieg, P. A., Rebagliati, M. R., Maniatis, T., Zinn, K., & Green, M. R. (1984) · Nucleic Acids Research · doi:10.1093/nar/12.18.7035 · Cited by 6,324
Gene regulation by steroid hormones
Beato, M. (1989) · Cell · doi:10.1016/0092-8674(89)90237-7 · Cited by 3,383
DNAase footprinting a simple method for the detection of protein-DNA binding specificity
Galas, D. J., & Schmitz, A. (1978) · Nucleic Acids Research · doi:10.1093/nar/5.9.3157 · Cited by 2,109
STEROID RECEPTOR REGULATED TRANSCRIPTION OF SPECIFIC GENES AND GENE NETWORKS
Yamamoto, K. R. (1985) · Annual Review of Genetics · doi:10.1146/annurev.ge.19.120185.001233 · Cited by 1,850
Functional domains of the human glucocorticoid receptor
Giguère, V., Hollenberg, S. M., Rosenfeld, M. G., & Evans, R. M. (1986) · Cell · doi:10.1016/0092-8674(86)90339-9 · Cited by 918
Potter, H., Weir, L., & Leder, P. (1984) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.81.22.7161 · Cited by 857
Chandler, V. L., Maler, B. A., & Yamamoto, K. R. (1983) · Cell · doi:10.1016/0092-8674(83)90430-0 · Cited by 697
Cited by
Sorted by citations
Items 101–200 of 281
Mantsch, J. R., Yuferov, V. P., Mathieu-Kia, A.-M., Ho, A., & Kreek, M. J. (2003) · Psychoneuroendocrinology · doi:10.1016/s0306-4530(02)00088-4 · Cited by 61
Nudi, M., Ouimette, J., & Drouin, J. (2005) · Molecular Endocrinology · doi:10.1210/me.2004-0425 · Cited by 61
Self-citationItoi, K., Seasholtz, A. F., & Watson, S. J. (1998) · Endocrine Journal · doi:10.1507/endocrj.45.13 · Cited by 62
Celada, A., McKercher, S. R., & Maki, R. A. (1993) · The Journal of Experimental Medicine · doi:10.1084/jem.177.3.691 · Cited by 59
Glucocorticoid repression of pro-opiomelanocortin gene transcription
Drouin, J., Lin, S. Y., & Nemer, M. J. (1989) · Journal of Steroid Biochemistry · doi:10.1016/0022-4731(89)90066-6 · Cited by 59
Self-citationZitnik, R. J., Whiting, N. L., & Elias, J. A. (1994) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/ajrcmb.10.6.7516173 · Cited by 59
Liu, W., Hillmann, A. G., & Harmon, J. M. (1995) · Molecular and Cellular Biology · doi:10.1128/mcb.15.2.1005 · Cited by 57
Effects of glucocorticoids on Fas gene expression in bovine blood neutrophils
Chang, L., Madsen‐Bouterse, S. A., Toelboell, T., Weber, P. S. D., & Burton, J. L. (2004) · Journal of Endocrinology · doi:10.1677/joe.1.05822 · Cited by 56
Hammer, G. D., Fairchild-Huntress, V., & Low, M. J. (1990) · Molecular Endocrinology · doi:10.1210/mend-4-11-1689 · Cited by 56
In vivo and in vitro inhibition of JE gene expression by glucocorticoids.
Poon, M., Megyesi, J., Green, R. S., Zhang, H., Rollins, B. J., Safirstein, R. L., & Taubman, M. B. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)54582-8 · Cited by 56
Pérez‐Martínez, L., Carreón‐Rodríguez, A., González-Alzati, M. E., Morales, C., Charli, J., & Joseph‐Bravo, P. (1998) · Neuroendocrinology · doi:10.1159/000054383 · Cited by 56
The cellular and molecular basis of the ectopic ACTH syndrome
White, A. E., & Clark, A. J. L. (1993) · Clinical Endocrinology · doi:10.1111/j.1365-2265.1993.tb01765.x · Cited by 55
Phi‐van, L., Spengler, D., & HOLSBOER, F. (1990) · Endocrinology · doi:10.1210/endo-127-3-1412 · Cited by 55
Heinrichs, A. A. J., Bortell, R., Rahman, S., Stein, J. L., Alnemri, E. S., Litwack, G., Lian, J. B., & Stein, G. S. (1993) · Biochemistry · doi:10.1021/bi00093a022 · Cited by 55
Cairns, C. A., Cairns, W. J., & Okret, S. (1993) · DNA and Cell Biology · doi:10.1089/dna.1993.12.695 · Cited by 55
Structural organization of the 5′ flanking region of the human corticotropin releasing hormone gene
Vamvakopoulos, N. C., & Chrousos, G. P. (1993) · DNA sequence · doi:10.3109/10425179309015632 · Cited by 50
Genes mediating glucocorticoid effects and mechanisms of their regulation
Geley, S., Fiegl, M., Hartmann, B. L., & Kofler, R. (1996) · Reviews of physiology, biochemistry and pharmacology · doi:10.1007/3-540-61343-9_7 · Cited by 49
Differential autoregulation of glucocorticoid receptor expression in human T- and B-cell lines
Denton, R., Eisen, L. P., Elsasser, M. S., & Harmon, J. M. (1993) · Endocrinology · doi:10.1210/endo.133.1.8319574 · Cited by 49
Regulation by estrogen through the 5'-flanking region of the mouse calbindin-D28k gene
Gill, R. K., & Christakos, S. (1995) · Molecular Endocrinology · doi:10.1210/mend.9.3.7776978 · Cited by 48
Temporally Tuned Corticosteroid Feedback Regulation of the Stress Axis
Kim, J. S., & Iremonger, K. J. (2019) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2019.07.005 · Cited by 44
Of old and new diseases: genetics of pituitary ACTH excess (Cushing) and deficiency
Drouin, J., Bilodeau, S., & Vallette-Kasic, S. (2007) · Clinical Genetics · doi:10.1111/j.1399-0004.2007.00877.x · Cited by 46
Self-citationPei, L. (1996) · Journal of Biological Chemistry · doi:10.1074/s0021-9258(19)73912-x · Cited by 46
Jin, W., Boutillier, A., Glucksman, M. J., Salton, S. R., Loeffler, J.-P., & Roberts, J. L. (1994) · Molecular Endocrinology · doi:10.1210/me.8.10.1377 · Cited by 45
Okabe, T., Takayanagi, R., Adachi, M., Imasaki, K., & Nawata, H. (1998) · Journal of Endocrinology · doi:10.1677/joe.0.1560169 · Cited by 44
Riegel, A. T., Lu, Y., Remenick, J., Wolford, R. G., Berard, D. S., & Hager, G. L. (1991) · Molecular Endocrinology · doi:10.1210/mend-5-12-1973 · Cited by 43
Aslam, F., Shalhoub, V., van Wijnen, A. J., Banerjee, C., Bortell, R., Shakoori, A. R., Litwack, G., Stein, J. L., Stein, G. S., & Lian, J. B. (1995) · Molecular Endocrinology · doi:10.1210/mend.9.6.8592514 · Cited by 43
Elevated Hypothalamic Glucocorticoid Levels Are Associated With Obesity and Hyperphagia in Male Mice
Sefton, C., Harno, E., Davies, A., Small, H. F., Allen, T.-J., Wray, J. R., Lawrence, C. B., Coll, A. P., & White, A. E. (2016) · Endocrinology · doi:10.1210/en.2016-1571 · Cited by 42
Subramaniam, N., Cairns, W. J., & Okret, S. (1997) · DNA and Cell Biology · doi:10.1089/dna.1997.16.153 · Cited by 42
Ray, A., LaForge, K. S., & Sehgal, P. B. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.16.7086 · Cited by 42
Complex structural and regulatory evolution of the pro-opiomelanocortin gene family
Harris, R. M., Dijkstra, P. D., & Hofmann, H. A. (2013) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2013.10.007 · Cited by 41
Herrlich, P. A., & Ponta, H. (1994) · Trends in Endocrinology and Metabolism · doi:10.1016/1043-2760(94)90164-3 · Cited by 41
The Mechanisms Underlying Autonomous Adrenocorticotropic Hormone Secretion in Cushing’s Disease
Fukuoka, H., Shichi, H., Yamamoto, M., & Takahashi, Y. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21239132 · Cited by 40
Molecular mechanisms of glucocorticoid inhibition of human proopiomelanocortin gene transcription
Nakai, Y., Usui, T., Tsukada, T., Takahashi, H., Fukata, J., Fukushima, M., Senoo, K., & Imura, H. (1991) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/0960-0760(91)90195-b · Cited by 38
Sarapura, V. D., Wood, W. M., Gordon, D. F., OCRAN, K. W., Kao, M. Y., & Ridgway, E. C. (1990) · Endocrinology · doi:10.1210/endo-127-3-1352 · Cited by 38
Iredale, P. A., & Duman, R. S. (1997) · Molecular Pharmacology · doi:10.1124/mol.51.5.794 · Cited by 37
Dexamethasone regulation of lung epithelial cell and fibroblast interleukin-11 production
Wang, J., Zhu, Z., Nolfo, R., & Elias, J. A. (1999) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.1999.276.1.l175 · Cited by 37
The Management of Glucocorticoid Therapy in Liver Failure
Xue, R., & Meng, Q. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.02490 · Cited by 37
The Glucocorticoid Receptor: A Revisited Target for Toxins
Marketon, J. I. W., & STERNBERG, E. M. (2010) · Toxins · doi:10.3390/toxins2061357 · Cited by 36
Shimojo, M., Hiroi, N., Yakushiji, F., Ueshiba, H., Yamaguchi, N., & Miyachi, Y. (1995) · Endocrine Journal · doi:10.1507/endocrj.42.629 · Cited by 36
Rani, C. S. S., Elango, N., Wang, S.-S., Kobayashi, K., & Strong, R. (2008) · Molecular Pharmacology · doi:10.1124/mol.108.051219 · Cited by 36
Cis-Active Determinants of Cardiac-Specific Expression in the Human Atrial Natriuretic Peptide Gene
Wu, J., Kovačič-Milivojević, B., LaPointe, M. C., Nakamura, K., & Gardner, D. G. (1991) · Molecular Endocrinology · doi:10.1210/mend-5-9-1311 · Cited by 36
Mehindate, K., Al‐Daccak, R., Schall, T. J., & Mourad, W. M. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)31601-6 · Cited by 35
Huizenga, N. A. T. M. (1998) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.83.3.917 · Cited by 33
The anti-inflammatory activity of glucocorticoids
de Waal, R. M. W. (1994) · Molecular Biology Reports · doi:10.1007/bf00997151 · Cited by 33
Regulation of Gene Expression by Steroid Hormones
Cato, A. C. B., Ponta, H., & Herrlich, P. A. (1992) · Progress in nucleic acid research and molecular biology · doi:10.1016/s0079-6603(08)61042-9 · Cited by 32
Riegel, A. T., Remenick, J., Wolford, R. G., Berard, D. S., & Hager, G. L. (1990) · Nucleic Acids Research · doi:10.1093/nar/18.15.4513 · Cited by 32
Glucocorticoid receptor gene polymorphisms in ACTH‐secreting pituitary tumours
Antonini, S. R. R., Latronico, A. C., Elias, L. L. K., Cukiert, A., Machado, H. R., Liberman, B., Mendonca, B. B., Moreira, A. C., & de Castro, M. (2002) · Clinical Endocrinology · doi:10.1046/j.1365-2265.2002.01639.x · Cited by 31
Transcript-specific effects of adrenalectomy on seizure-induced BDNF expression in rat hippocampus
Lauterborn, J. C., Poulsen, F. R., Stinis, C., Isackson, P. J., & Gall, C. M. (1998) · Molecular Brain Research · doi:10.1016/s0169-328x(97)00368-9 · Cited by 31
Cloning and Characterization of the Proximal Murine Phex Promoter
Liu, S., Guo, R., & Quarles, L. D. (2001) · Endocrinology · doi:10.1210/en.142.9.3987 · Cited by 31
Garlatti, M., Daheshia, M., Slater, E. P., Bouguet, J., Hanoune, J., Beato, M., & Barouki, R. (1994) · Molecular and Cellular Biology · doi:10.1128/mcb.14.12.8007-8017.1994 · Cited by 31
Lee, J., Moffitt, P. G., Morley, K. L., & Peterson, D. O. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)54399-4 · Cited by 31
Kang, S. W., & Kuenzel, W. J. (2014) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2014.04.018 · Cited by 31
Link, H., Dayanithi, G., & Gratzl, M. (1993) · Endocrinology · doi:10.1210/endo.132.2.8381078 · Cited by 30
Yin, J., & Howells, R. (1992) · Molecular Brain Research · doi:10.1016/0169-328x(92)90083-n · Cited by 30
Autelitano, D. J. (1994) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.1994.tb00629.x · Cited by 29
Human immune deficiency virus (HIV) infection and the hypothalamic pituitary adrenal axis
George, M. M., & Bhangoo, A. (2013) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-013-9244-x · Cited by 28
Autelitano, D. J., & Sheppard, K. E. (1993) · Molecular and Cellular Endocrinology · doi:10.1016/0303-7207(93)90058-r · Cited by 27
Tseng, Y., Stabila, J. P., Nguyen, T. T., McGonnigal, B., Waschek, J. A., & Padbury, J. F. (2001) · Molecular and Cellular Endocrinology · doi:10.1016/s0303-7207(01)00490-7 · Cited by 27
Bitondo, R. D. (2002) · Human Molecular Genetics · doi:10.1093/hmg/11.7.723 · Cited by 27
Steroids and growth promoting factors in the regulation of expression of genes and gene networks
Cato, A. C. B., König, H., Ponta, H., & Herrlich, P. A. (1992) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/0960-0760(92)90188-o · Cited by 25
Expression of cardiotoxin‐2 gene
Ma, D., Armugam, A., & Jeyaseelan, K. (2001) · European Journal of Biochemistry · doi:10.1046/j.1432-1327.2001.02059.x · Cited by 23
Nishi, M., & Azmitia, E. C. (1996) · Brain Research · doi:10.1016/0006-8993(96)00193-x · Cited by 22
van der Laan, S., de Kloet, E. R., & Meijer, O. C. (2009) · PLoS ONE · doi:10.1371/journal.pone.0004327 · Cited by 21
Proteomic analysis of the cortisol‐mediated stress response in THP‐1 monocytes using DIGE technology
Billing, A. M., Fack, F., Renaut, J., Olinger, C. M., Schote, A. B., Turner, J. D., & Muller, C. P. (2007) · Journal of Mass Spectrometry · doi:10.1002/jms.1270 · Cited by 22
Marchi, D., & van Eeden, F. J. M. (2021) · Cells · doi:10.3390/cells10123441 · Cited by 21
Role of NeuroD1 on the negative regulation of Pomc expression by glucocorticoid
Parvin, R., Saito‐Hakoda, A., Shimada, H., Shimizu, K., Noro, E., Iwasaki, Y., Fujiwara, K., Yokoyama, A., & Sugawara, A. (2017) · PLoS ONE · doi:10.1371/journal.pone.0175435 · Cited by 20
Regulatory Elements of the Human Proopiomelanocortin Gene Promoter
Kraus, J., Buchfelder, M., & Höllt, V. (1993) · DNA and Cell Biology · doi:10.1089/dna.1993.12.527 · Cited by 20
Structural analysis of the entire proopiomelanocortin gene ofXenopus laevis
Deen, P. M. T., Terwel, D., Bussemakers, M. J. G., Roubos, E. W., & Martens, G. J. M. (1991) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1991.tb16265.x · Cited by 20
Therrien, M., & Drouin, J. (1993) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1993.tb19768.x · Cited by 20
Self-citationVasopressin in the regulation of body functions
Mohr, E., & Richter, D. (1996) · Springer eBooks · doi:10.1007/978-94-009-0083-7_19 · Cited by 19
Regulation of Opioid Peptide Gene Expression
Höllt, V. (1993) · Handbook of experimental pharmacology · doi:10.1007/978-3-642-77460-7_14 · Cited by 20
Bruhn, T. O., Bolduc, T. G., Rondeel, J. M. M., & JACKSON, I. M. D. (1994) · Endocrinology · doi:10.1210/endo.134.2.8299577 · Cited by 20
Kageyama, K., Iwasaki, Y., Watanuki, Y., Niioka, K., & Daimon, M. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22115724 · Cited by 21
DNA-binding by the glucocorticoid receptor: A structural and functional analysis
Dahlman, K., Wright, A. P. H., Carlstedt‐Duke, J., & Gustafsson, J. (1992) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/0960-0760(92)90351-i · Cited by 19
Necela, B. M., & Cidlowski, J. A. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m405489200 · Cited by 19
Glucocorticoid regulation of thymidine kinase (Tk-1) expression in L929 cells.
Frost, G. H., Rhee, K.-Y., & Thompson, E. A. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)53313-5 · Cited by 19
Murakami, I., Takeuchi, S., Kudo, T., Sutou, S., & Takahashi, S. (2007) · Journal of Endocrinology · doi:10.1677/joe-06-0143 · Cited by 18
Hess, P., Meenakshi, T., Chan, G. C. ‐., Carlstedt‐Duke, J., Gustafsson, J.-Α., & Payvar, F. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.7.2564 · Cited by 18
Repression Mechanisms of v‐ERBA and Other Members of the Steroid Receptor Superfamily
Renkawitz, R. (1993) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1993.tb32266.x · Cited by 18
Tricyclic antidepressants target FKBP51 SUMOylation to restore glucocorticoid receptor activity
Budziñski, M. L., Sokn, C., Gobbini, R., Ugo, B., Antunica-Noguerol, M., Senin, S., Bajaj, T., Gassen, N. C., Rein, T., Schmidt, M. V., et al. (2022) · Molecular Psychiatry · doi:10.1038/s41380-022-01491-0 · Cited by 17
Expression of cardiotoxin-2 gene Cloning, characterization and deletion analysis of the promoter
Ma, D., Armugam, A., & Jeyaseelan, K. (2001) · European Journal of Biochemistry · doi:10.1046/j.1432-1033.2001.02059.x · Cited by 17
The α-foetoprotein proximal enhancer: localization, cell specificity and modulation by dexamethasone
Houart, C., Szpirer, J., & Szpirer, C. (1990) · Nucleic Acids Research · doi:10.1093/nar/18.21.6277 · Cited by 17
Latchoumanin, O., Mynard, V., Leclerc, J., Dugué, M.-A., BERTAGNA, X. Y., & CATELLI, M. G. (2006) · Endocrinology · doi:10.1210/en.2006-0460 · Cited by 14
Wan, Y.-J. Y., & Wu, T.-C. J. (1992) · Differentiation · doi:10.1111/j.1432-0436.1992.tb00491.x · Cited by 15
Turney, M. K., & Kovacs, W. J. (2001) · Journal of Molecular Endocrinology · doi:10.1677/jme.0.0260043 · Cited by 15
Burnstein, K. L., Jewell, C. M., & Cidlowski, J. A. (1991) · Molecular Endocrinology · doi:10.1210/mend-5-7-1013 · Cited by 15
Tristetraprolin is involved in the glucocorticoid-mediated interleukin 8 repression
Shi, J., Li, J., Hu, R., Shi, Y. P., Su, X., Guo, X., & Li, X.-M. (2014) · International Immunopharmacology · doi:10.1016/j.intimp.2014.07.031 · Cited by 14
Drouin, J., Lin, S. Y., & Nemer, M. J. (1990) · Trends in Endocrinology and Metabolism · doi:10.1016/1043-2760(90)90056-9 · Cited by 14
Self-citationWellstein, A., Dobrenski, A. F., Radonovich, M. N., Brady, J. F., & Riegel, A. T. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)98887-3 · Cited by 14
11 Structure and Regulation of Genes for Estrogen Receptors
Dréan, Y. L., Pakdel, F., & Valotaire, Y. (1994) · Fish physiology · doi:10.1016/s1546-5098(08)60072-2 · Cited by 14
Nuclear Receptors as Regulators of Pituitary Corticotroph Pro-Opiomelanocortin Transcription
Zhang, D., & Heaney, A. P. (2020) · Cells · doi:10.3390/cells9040900 · Cited by 13
Vetrovoy, O. V., Stratilov, V. A., Lomert, E. V., & Tyulkova, E. I. (2022) · Neurochemical Research · doi:10.1007/s11064-022-03837-0 · Cited by 13
Teshima, T., Hara, Y., Takekoshi, S., Teramoto, A., OSAMURA, R. Y., & TAGAWA, M. (2008) · Domestic Animal Endocrinology · doi:10.1016/j.domaniend.2008.08.002 · Cited by 13
Proopiomelanocortin gene and gene products: A comparative study
Duvaux-Miret, O., & Capron, A. (1991) · Advances in Neuroimmunology · doi:10.1016/s0960-5428(06)80031-8 · Cited by 13
Analysis of proopiomelanocortin gene transcription mechanisms in bronchial tumour cells
Picon, A., BERTAGNA, X. Y., & de Keyzer, Y. (1999) · Molecular and Cellular Endocrinology · doi:10.1016/s0303-7207(98)00215-9 · Cited by 13
Groves, T., Wagner, G. F., & DiMattia, G. E. (2001) · Journal of Endocrinology · doi:10.1677/joe.0.1710499 · Cited by 12
Therapeutic implications of the nuclear factor-kappaB/nuclear receptor cross-talk
Gossye, V. (2008) · Frontiers in bioscience · doi:10.2741/2997 · Cited by 12
The 5′-Flanking Sequence and Regulatory Elements of the Cystatin S Gene
Shaw, P. A., & Chaparro, O. (1999) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1999.1072 · Cited by 12
Opioid Peptide Genes: Structure and Regulation
Höllt, V. (1991) · Springer eBooks · doi:10.1007/978-3-642-46660-1_2 · Cited by 12
Vinterstare, J., Brönmark, C., Nilsson, P. A., Langerhans, R. B., Chauhan, P., Hansson, B., & Hulthén, K. (2022) · Evolution · doi:10.1093/evolut/qpac030 · Cited by 11
Metadata
- Authors
- Drouin, J., Trifiro, M. A., Plante, R. K., Nemer, M., Eriksson, P., & Wrange, Ö.
- Affiliations
- Montreal Clinical Research Institute (CA)
- Karolinska Institutet (SE)
- Department of Molecular Genetics, Karolinska Institutet
- Venue
- Molecular and Cellular Biology
- Publisher
- Informa UK Limited
- Published
- 1989-12
- Volume
- 9
- Issue
- 12
- Pages
- 5305-5314
- ISSN
- 0270-7306 (ISSN-L)
- 1098-5549
- PMC
- PMC363695
- OpenAlex
- W2161628453
- Cited by
- 283
- References
- 71
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 2 · 2023: 3 · 2022: 5 · 2021: 5 · 2020: 4 · 2019: 4 · 2018: 5 · 2017: 2 · 2016: 5 · 2015: 3 · 2014: 2 · 2013: 6 · 2012: 2
- FWCI
- 12.99
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Molecular and Cellular Biology (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Endocrinology › Estrogen and related hormone effects
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Chromatin Dynamics
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Keywords
- glucocorticoid receptor, transcriptional repression, glucocorticoid response element, anterior pituitary, AtT-20 cells, sequence divergence
- MeSH terms
- Animals, Base Sequence, DNA, Genes, Molecular Sequence Data, Nucleotide Mapping, Pituitary Gland, Anterior, Plasmids, Pro-Opiomelanocortin, Protein Binding, Receptors, Glucocorticoid, Suppression, Genetic, Transcription, Genetic, Restriction Mapping, Rats
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review