The DOI matches its Crossref record.
N-ras mutations in human cutaneous melanoma from sun-exposed body sites.
Open accessAbstract
In 7 of 37 patients with cutaneous melanoma, mutations in the N-ras gene were found. The primary tumors of these seven patients were exclusively localized on body sites continuously exposed to sunlight. Moreover, the ras mutations were all at or near dipyrimidine sites known to be targets of UV damage. Two primary tumors were biclonal with respect to ras mutation. An active role for UV irradiation in induction of the mutations is suggested.
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Citations
Cited by
Mutations of the BRAF gene in human cancer
Davies, H., Bignell, G. R., Cox, C., Stephens, P., Edkins, S., Clegg, S., Teague, J., Woffendin, H., Garnett, M. J., Bottomley, W., et al. (2002) · Nature · doi:10.1038/nature00766 · Cited by 10,674
Lee, J.-H., Choi, J.-W., & Kim, Y.-S. (2011) · British Journal of Dermatology · doi:10.1111/j.1365-2133.2010.10185.x · Cited by 419
Edlundh-Rose, E., Egyha??zi, S., Omholt, K., Mansson-Brahme, E., Platz, A., Hansson, J., & Lundeberg, J. (2006) · Melanoma Research · doi:10.1097/01.cmr.0000232300.22032.86 · Cited by 318
Photocarcinogenesis: UVA vs. UVB Radiation
de Gruijl, F. R. (2002) · Skin Pharmacology and Physiology · doi:10.1159/000064535 · Cited by 315
Si, L., Kong, Y., Xu, X., Flaherty, K. T., Sheng, X., Cui, C., Chi, Z., Li, S., Mao, L., & Guo, J. (2012) · European Journal of Cancer · doi:10.1016/j.ejca.2011.06.056 · Cited by 255
Metadata
- Authors
- van 't Veer, L. J., Burgering, B. M., Versteeg, R., Boot, A. J., Ruiter, D. J., Osanto, S., Schrier, P. I., & Bos, J. L.
- Venue
- Molecular and Cellular Biology
- Publisher
- Informa UK Limited
- Published
- 1989-07
- Volume
- 9
- Issue
- 7
- Pages
- 3114-3116
- ISSN
- 0270-7306 (ISSN-L)
- 1098-5549
- OpenAlex
- W2171733999
- Cited by
- 283
- References
- 0
- FWCI
- 4.34
- Type
- journal article
- Language
- en
- Open access
- green
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- van 't Veer, L. J., Burgering, B. M., Versteeg, R., Boot, A. J., Ruiter, D. J., Osanto, S., Schrier, P. I., & Bos, J. L. (1989). N-ras mutations in human cutaneous melanoma from sun-exposed body sites. Molecular and Cellular Biology. https://doi.org/10.1128/mcb.9.7.3114
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
