Culture-Independent Detection of Poliovirus in Stool Samples by Direct RNA Extraction
Open accessAbstract
The GPLN is a global surveillance system composed of 146 laboratories in 92 countries, in each of the six World Health Organization regions. Laboratory surveillance for PV relies on virus isolation by cell culture to identify PV in stool samples from AFP cases.
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References 29 · Cited by 25
- Authors
- Harrington, C., Sun, H., Jeffries-Miles, S., Gerloff, N., Mandelbaum, M., Pang, H., Collins, N., Burns, C. C., & Vega, E.
- Affiliations
- Centers for Disease Control and Prevention (US)
- Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
- Cherokee Nation (US)
- IHRC, Inc., contracting agency to the Division of Viral Diseases, Atlanta, Georgia, USA
- Corresponding author
- Harrington, Chelsea
- ORCID
- Venue
- Microbiology Spectrum
- Publisher
- American Society for Microbiology
- Published
- 2021-12-22
- Volume
- 9
- Issue
- 3
- Pages
- e0066821-e0066821
- ISSN
- 2165-0497 (ISSN-L)
- PMC
- PMC8579935
- OpenAlex
- W3213033580
- Cited by
- 25
- References
- 29
- Citations by year
- 2026: 3 · 2025: 3 · 2024: 12 · 2023: 5 · 2022: 2
- FWCI
- 3.35
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Microbiology Spectrum (publishedVersion, cc-by)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- HHS | Centers for Disease Control and Prevention
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Viral Infections and Immunology Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Molecular Biology Techniques and Applications
- Health Sciences › Medicine › Infectious Diseases › Viral gastroenteritis research and epidemiology
- Keywords
- poliovirus, culture-independent detection, fecal samples, acute flaccid paralysis, polio surveillance, real-time RT-PCR, Global Polio Eradication Initiative
- MeSH terms
- Feces, Humans, Poliomyelitis, Prospective Studies, Retrospective Studies, RNA, Viral, Poliovirus, Clinical Laboratory Techniques, Real-Time Polymerase Chain Reaction
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