Semax prevents learning and memory inhibition by heavy metals
Abstract
Separate and joint effect of Semax, ascorbic acid, lead diacetate, and ammonium molybdate on avoidance conditioning in rats was studied. It was established that the heavy metal salts inhibited the avoidance response, and the peptide counteracted this inhibition as strongly as ascorbic acid or to a comparable degree. These findings confirm the antioxidant properties of Semax.
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The neuroprotective and neurotrophic effects of Semax are reliably established.
“The neuroprotective and neurotrophic effects of Semax are reliably established [1,2,3,4,5,6,7,8].”
Cited by
Sorted by citations
Filippenkov, I. B., Stavchansky, V. V., Denisova, A. E., Yuzhakov, V. V., Sevan’kaeva, L. E., Sudarkina, O. Y., Dmitrieva, V. G., Gubsky, L. V., Myasoedov, N. F., Limborska, S. A., et al. (2020) · Genes · doi:10.3390/genes11060681 · Cited by 29 · see citing works
Self-citation
- Authors
- Inozemtsev, A. N., Bokieva, S. B., Karpukhina, O. V., Gumargalieva, K. Z., Kamensky, A. A., & Myasoedov, N. F.
- Affiliations
- Lomonosov Moscow State University (RU)
- North Ossetian State University (RU)
- Russian Academy of Sciences (RU)
- Corresponding author
- Inozemtsev, A. N.
- Venue
- Doklady Biological Sciences
- Publisher
- Pleiades Publishing Ltd
- Published
- 2016-05
- Volume
- 468
- Issue
- 1
- Pages
- 112-114
- ISSN
- 0012-4966 (ISSN-L)
- 1608-3105
- OpenAlex
- W2465577428
- Cited by
- 3
- References
- 0
- Citations by year
- 2022: 1 · 2020: 1 · 2019: 1
- FWCI
- 0.21
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Doklady Biological Sciences (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Heavy Metal Exposure and Toxicity
- Health Sciences › Nursing › Nutrition and Dietetics › Trace Elements in Health
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Keywords
- Semax, heavy metal toxicity, ammonium molybdate, vitamin C, avoidance conditioning, learning and memory, antioxidant activity, neuroprotection, peptides
- MeSH terms
- Adrenocorticotropic Hormone, Animals, Antioxidants, Avoidance Learning, Male, Memory, Molybdenum, Organometallic Compounds, Peptide Fragments, Rats
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