The DOI matches its Crossref record; 34 of the 34 references it cites were found in a registry or an index.
Lichen sclerosus et atrophicus and sexual abuse.
Open accessAbstract
AIMS: The aetiology of lichen sclerosus et atrophicus (LSA) is unknown. A series of 42 cases of this uncommon condition is reported. The aim of this study was to identify associations of LSA and document the association with sexual abuse. METHODS: Information about the patients was obtained by retrospective case note review and some patients were contacted by telephone for further information. RESULTS: In 12 cases there was evidence of sexual abuse. The abused group were slightly older than the non-abused group but were similar in all other respects. All three patients who presented over the age of 12 years had evidence of sexual abuse. Genital trauma was recalled by the patient or found at examination in 17 cases. Evidence of autoimmunity was present in five cases. Positive microbiological isolates were obtained in 18 cases. In only 11 cases were there no associated factors. The symptoms of LSA started between the ages of 3 and 7 years in most patients. The usual symptoms were related to genital skin involvement, and symptoms related to bladder and bowel function were common (50%). CONCLUSION: In this large series of paediatric LSA, associations with trauma, autoimmunity, and infection were noted. There was a high rate of coexisting sexual abuse with LSA, possibly due to genital trauma.
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Cites
Lichen sclerosus et atrophicus and autoimmunity—a study of 350 women
THOMAS, R. H. M., Ridley, C. M., McGibbon, D., & Black, M. M. (1988) · British Journal of Dermatology · doi:10.1111/j.1365-2133.1988.tb01748.x · Cited by 353
Lichen sclerosus et atrophicus
Wallace, H. J. (2004) · Springer eBooks · doi:10.1007/3-540-29668-9_1604 · Cited by 307
HARRINGTON, C. I., & DUNSMORE, I. R. (1981) · British Journal of Dermatology · doi:10.1111/j.1365-2133.1981.tb08172.x · Cited by 210
Serum Levels of Sex Hormones in Vulvar Lichen Sclerosus, and the Effect of Topical Testosterone
Friedrich, E. G., & Kalra, P. S. (1984) · New England Journal of Medicine · doi:10.1056/nejm198402233100803 · Cited by 144
Organ-specific Antibodies in Patients with Lichen Sclerosus
Goolamali, S. K., Barnes, E. W., Irvine, W. J., & Shuster, S. (1974) · BMJ · doi:10.1136/bmj.4.5936.78 · Cited by 109
Lichen sclerosus et atrophicus. A common and distinctive cause of phimosis in boys
Chalmers, R. J. G. (1984) · Archives of Dermatology · doi:10.1001/archderm.120.8.1025 · Cited by 106
The association of lichen sclerosus et atrophicus and autoimmune-related disease in males
Thomas, R., Ridley, C. M., & Black, M. M. (1983) · British Journal of Dermatology · doi:10.1111/j.1365-2133.1983.tb00546.x · Cited by 103
The development of lichen sclerosus et atrophicus in monozygotic twin girls
Thomas, R., & Kennedy, C. (1986) · British Journal of Dermatology · doi:10.1111/j.1365-2133.1986.tb02831.x · Cited by 88
Lichen Sclerosus et Atrophicus
Chalmers, R. J. G. (1984) · Archives of Dermatology · doi:10.1001/archderm.1984.01650440055019 · Cited by 87
Lichen sclerosus et atrophicus in children misdiagnosed as sexual abuse.
Handfield-Jones, S. E., Hinde, F. R., & Kennedy, C. T. (1987) · BMJ · doi:10.1136/bmj.294.6584.1404 · Cited by 73
Research works printed but not linked: 2
- Goolamali SK, Barnes EW, Irvine WJ, Shuster S. Organspecific antibodies in patients with lichen sclerosus. BMJ 1974;iv:78-9.
- de San Lazaro C. Lichen sclerosus [letter]. Arch Dis Child 1990;65:1 184.
Cited by
Sorted by citations
Childhood vulvar lichen sclerosus: An increasingly common problem
Powell, J., & Wojnarowska, F. (2001) · Journal of the American Academy of Dermatology · doi:10.1067/mjd.2001.113474 · Cited by 274
Lichen Sclerosus—Presentation, Diagnosis and Management
Kirtschig, G. (2016) · Deutsches Ärzteblatt international · doi:10.3238/arztebl.2016.0337 · Cited by 185
Wood, P. L., & Bevan, T. (1999) · BMJ · doi:10.1136/bmj.319.7214.899 · Cited by 33
Lichen Sclerosus in the Differential Diagnosis of Suspected Child Abuse Cases
Isaac, R., Lyn, M., & Triggs, N. (2007) · Pediatric Emergency Care · doi:10.1097/01.pec.0000280513.98289.e8 · Cited by 18
Te, B., Julien, D., Mar, K., Liu, R., & Kirshen, C. (2026) · Pediatric Dermatology · doi:10.1111/pde.70112 · Cited by 2
Metadata
- Authors
- Warrington, S. A., & de San Lazaro, C.
- Affiliations
- Royal Victoria Infirmary (GB)
- Venue
- Archives of Disease in Childhood
- Publisher
- BMJ
- Published
- 1996-12-01
- Volume
- 75
- Issue
- 6
- Pages
- 512-516
- ISSN
- 0003-9888 (ISSN-L)
- 1468-2044
- PMC
- PMC1511802
- OpenAlex
- W2171856339
- Cited by
- 80
- References
- 34
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 4 · 2023: 1 · 2021: 4 · 2020: 2 · 2019: 2 · 2018: 3 · 2017: 3 · 2016: 2 · 2015: 2 · 2013: 2 · 2012: 2
- FWCI
- 2.91
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Archives of Disease in Childhood (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Genital Health and Disease
- Health Sciences › Medicine › Urology › Urological Disorders and Treatments
- Social Sciences › Psychology › Clinical Psychology › Child Abuse and Trauma
- Keywords
- lichen sclerosus, sexual abuse, genital trauma, pediatric patients, autoimmunity, infection, etiology, bowel and bladder dysfunction, childhood onset
- MeSH terms
- Adolescent, Age Factors, Autoimmune Diseases, Child, Child Abuse, Sexual, Child, Preschool, Diagnosis, Differential, Female, Genitalia, Female, Humans, Referral and Consultation, Retrospective Studies, Lichen Sclerosus et Atrophicus
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